PKNX1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PKNX1_MOUSE
• UniProt AC: O70477
• Protein Name: Homeobox protein PKNOX1
• Gene Name: Pknox1
• Organism: Mus musculus (Mouse).
• Sequence Length: 436
• Subcellular Localization: Nucleus .
• Protein Sequence: MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	TQTLSIDSYQDGQQM CEEEEEECCCCCCEE	24.03	29899451
26	Phosphorylation	QVVTELKTEQDPNCS EEEEEEECCCCCCCC	52.05	23608596
33	Phosphorylation	TEQDPNCSDPDAEGV CCCCCCCCCCCCCCC	59.84	22817900
41	Phosphorylation	DPDAEGVSPPPIESQ CCCCCCCCCCCCCCC	42.41	22817900
47	Phosphorylation	VSPPPIESQTPMDAD CCCCCCCCCCCCCCC	39.82	22817900
49	Phosphorylation	PPPIESQTPMDADKQ CCCCCCCCCCCCCHH	29.84	25195567
360	Phosphorylation	GVAQATPSELAMSEG CCCCCCHHHHHCCCC	40.67	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PKNX1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PKNX1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PKNX1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PBX2_MOUSE	Pbx2	physical	17623278
ACTB_MOUSE	Actb	physical	17623278
MBB1A_MOUSE	Mybbp1a	physical	17623278
MYH9_MOUSE	Myh9	physical	17623278
PBX1_MOUSE	Pbx1	physical	17623278
RS3A_MOUSE	Rps3a1	physical	17623278
PBX1_MOUSE	Pbx1	physical	10654609

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.