| UniProt ID | ORC5_SCHPO | |
|---|---|---|
| UniProt AC | O43114 | |
| Protein Name | Origin recognition complex subunit 5 | |
| Gene Name | orc5 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 455 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. ORC binds to multiple sites within the ars1 origin of DNA replication in an ATP-independent manner.. | |
| Protein Sequence | MHLYQLEDELKKNVFCREDQIKKLSCLLFNKDCRVPSIVLYGVASTAKTFLLRTAFDLSKEENVWINLQDCFTVAHFWYRILIKVGVDKDIALKKGINISGFIYLLEQAMSKRDYHTFLVLDQIDDFAEASTILFSQLAQLPIVANIPNLSIIFVLHSHPAQYLGTLSIAVIFFPQYTQAEILEICQKTPPNLDFLDRSGDSVFEDEIELSVWMQYCSFLWSVFGVQCLNDYRSFRSVLDRYWPKFIQPIVEGDIHPADYAQLHKLAKNFLVSDATVTKRLHIINPTEIKNLLDSKSINLSLVSKYLLVSAFLASYNPSRLDAQFFSFSKTSKRRGRKRKQIQDEGVLFSKIPRTAGSKGRSAVKISQLTLGPKPFEVERLIAIYYAISSPVEKVLTADVFVQIATLASLKMILSASKGVLRSLDSPRYIVNVSREYVLKIADSLSFPLDSYLAG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of ORC5_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ORC5_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ORC5_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ORC5_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CUT1_SCHPO | cut1 | genetic | 15507118 | |
| SMC2_SCHPO | cut14 | genetic | 15507118 | |
| SMC4_SCHPO | cut3 | genetic | 15507118 | |
| ORC2_SCHPO | orc2 | physical | 10535928 | |
| ORC4_SCHPO | orc4 | physical | 10535928 | |
| ORC1_SCHPO | orc1 | physical | 10535928 | |
| ORC3_SCHPO | orc3 | physical | 10535928 | |
| ORC6_SCHPO | orc6 | physical | 10535928 | |
| ORC6_SCHPO | orc6 | physical | 11850415 | |
| ORC1_SCHPO | orc1 | physical | 10523506 | |
| ORC2_SCHPO | orc2 | physical | 11689699 | |
| ORC3_SCHPO | orc3 | physical | 11689699 | |
| ORC1_SCHPO | orc1 | physical | 11689699 | |
| ORC6_SCHPO | orc6 | physical | 11689699 | |
| ORC1_SCHPO | orc1 | physical | 18723846 | |
| ORC2_SCHPO | orc2 | physical | 18723846 | |
| ORC3_SCHPO | orc3 | physical | 18723846 | |
| ORC4_SCHPO | orc4 | physical | 18723846 | |
| ORC6_SCHPO | orc6 | physical | 18723846 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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