NOG1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NOG1_DROME
• UniProt AC: Q9V411
• Protein Name: Nucleolar GTP-binding protein 1
• Gene Name: Non1 {ECO:0000312|FlyBase:FBgn0028473}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 652
• Subcellular Localization: Nucleus, nucleolus . Found in the nucleolus during interphase.
• Protein Description: Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. [PubMed: 24255106 May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs]
• Protein Sequence: MSLYNFKKIMVVPPAKDFIDIMLSKTQRKTPTVVHKGYKISRIRAFYTRKVKYTQQNFHDRLSQIIQDFPKLDDVHPFYADLMNVLYDKDHYKLALGQLNTARHLVDNVAKDYVRLLKYGDSLYRCKQLKKAALGRMATIMKRQASNLTYLEQVRQHLSRLPTIDPYSRTIIICGFPNVGKSSFINKITRADVEVQPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAITALAHLRACVLYFMDISEQCGHSLEEQVKLFESIKPLFTNKPLILAINKIDILTPEDLPEERRAIITKLQEDKNIPVMLMSTVQETGVMEVKTEACERLLSYRVDQKMRTKKVDNILNRLHVAMPAPRDDKLRAPCIPEKASARLLQNADKAERKRKLEKEIEEEMGDDYTLDLKKNYSEIPEEERYDIIPEFWQGHNIADYIDADIFDKLEELEREEGLREESGVYKVPDMTMDETLKEIREIAKQIRGKRFELRDEKRLSSRKNKPVIPRNKQPKVRDRSVQKLVSTMEGLGVDMSGSENANFTKSVVDLRRGQVAVGSKKVPMQPLLDKESSAVVRKTGQPLKRAPSRDTLGIKNLAIRKKAQIMAKRDIAKKVTSRGLKGEADRFIGTKMPKHLFSGKRGNGKTDRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
582	Phosphorylation	SSAVVRKTGQPLKRA CCHHHHHCCCCCCCC	30.41	29892262
591	Phosphorylation	QPLKRAPSRDTLGIK CCCCCCCCCCCCCCC	41.63	19429919
594	Phosphorylation	KRAPSRDTLGIKNLA CCCCCCCCCCCCHHH	26.27	22817900
598	Acetylation	SRDTLGIKNLAIRKK CCCCCCCCHHHHHHH	44.07	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NOG1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NOG1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NOG1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GNL3_DROME	Ns1	physical	22036573
RLP24_DROME	RpL24-like	physical	22036573
BOP1_DROME	CG5033	physical	22036573
RPF1_DROME	CG6712	physical	22036573
NOC3L_DROME	CG1234	physical	22036573
IF6_DROME	eIF6	physical	22036573
RRP12_DROME	CG2691	physical	22036573
PESC_DROME	CG4364	physical	22036573

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.