BOP1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BOP1_DROME
• UniProt AC: Q7K0Y1
• Protein Name: Ribosome biogenesis protein BOP1 homolog {ECO:0000255|HAMAP-Rule:MF_03027}
• Gene Name: CG5033
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 784
• Subcellular Localization: Nucleus, nucleolus . Nucleus, nucleoplasm .
• Protein Description: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit..
• Protein Sequence: MTKKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDAKKIIKPPQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEDIALIKRIVSGRIPNKDHEEYEPWIEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVSRMVHALKMGWMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTIETDEVVRCVAWCPNPKLSIIAVATGNRLLLVNPKVGDKVLVKKTDDLLAEAPSQDVIESERIKTAVQWSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVATQHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKRDEFGVLDVNWHPVQPWVFSTGADSTIRLYT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	PTNEVVASSEASENE CCCCCCCCCCCCCCH	19.66	19429919
24	Phosphorylation	TNEVVASSEASENEE CCCCCCCCCCCCCHH	27.69	19429919
27	Phosphorylation	VVASSEASENEEEEE CCCCCCCCCCHHHHH	36.58	19429919
148	Phosphorylation	RDSSKPEYQDSDTSD CCCCCCCCCCCCCCC	26.58	19429919
151	Phosphorylation	SKPEYQDSDTSDEED CCCCCCCCCCCCHHH	27.54	19429919
153	Phosphorylation	PEYQDSDTSDEEDIR CCCCCCCCCCHHHHH	41.87	19429919
154	Phosphorylation	EYQDSDTSDEEDIRN CCCCCCCCCHHHHHH	48.27	19429919
538	Phosphorylation	DLLAEAPSQDVIESE HHHHHCCCCCHHHHH	46.17	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BOP1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BOP1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BOP1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EIF3L_DROME	CG5642	physical	14605208
RPF1_DROME	CG6712	physical	22036573
WDR12_DROME	CG6724	physical	22036573

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.