NIA1_ARATH - dbPTM
NIA1_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NIA1_ARATH
UniProt AC P11832
Protein Name Nitrate reductase [NADH] 1
Gene Name NIA1
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 917
Subcellular Localization
Protein Description Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria..
Protein Sequence MATSVDNRHYPTMNGVAHAFKPPLVPSPRSFDRHRHQNQTLDVILTETKIVKETEVITTVVDSYDDSSSDDEDESHNRNVPYYKELVKKSNSDLEPSILDPRDESTADSWIQRNSSMLRLTGKHPFNAEAPLPRLMHHGFITPVPLHYVRNHGAVPKANWSDWSIEITGLVKRPAKFTMEELISEFPSREFPVTLVCAGNRRKEQNMVKQTIGFNWGSAGVSTSLWKGIPLSEILRRCGIYSRRGGALNVCFEGAEDLPGGGGSKYGTSIKKEMAMDPARDIILAYMQNGELLTPDHGFPVRVIVPGFIGGRMVKWLKRIIVTPQESDSYYHYKDNRVLPSLVDAELANSEAWWYKPEYIINELNINSVITTPGHAEILPINAFTTQKPYTLKGYAYSGGGKKVTRVEVTLDGGDTWSVCELDHQEKPNKYGKFWCWCFWSLDVEVLDLLSAKDVAVRAWDESFNTQPDKLIWNLMGMMNNCWFRIRTNVCKPHRGEIGIVFEHPTRPGNQSGGWMAKERQLEISSESNNTLKKSVSSPFMNTASKMYSISEVRKHNTADSAWIIVHGHIYDCTRFLKDHPGGTDSILINAGTDCTEEFEAIHSDKAKKLLEDYRIGELITTGYDSSPNVSVHGASNFGPLLAPIKELTPQKNIALVNPREKIPVRLIEKTSISHDVRKFRFALPSEDQQLGLPVGKHVFVCANINDKLCLRAYTPTSAIDAVGHIDLVVKVYFKDVHPRFPNGGLMSQHLDSLPIGSMIDIKGPLGHIEYKGKGNFLVSGKPKFAKKLAMLAGGTGITPIYQIIQSILSDPEDETEMYVVYANRTEDDILVREELEGWASKHKERLKIWYVVEIAKEGWSYSTGFITEAVLREHIPEGLEGESLALACGPPPMIQFALQPNLEKMGYNVKEDLLIF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
27PhosphorylationFKPPLVPSPRSFDRH
CCCCCCCCCCCCCCC		26.0129654922
30PhosphorylationPLVPSPRSFDRHRHQ
CCCCCCCCCCCCCCC		34.5823172892
40PhosphorylationRHRHQNQTLDVILTE
CCCCCCCCCCEEEEC		32.2619880383
58PhosphorylationVKETEVITTVVDSYD
EEEEEEEEEEEECCC		20.7923776212
59PhosphorylationKETEVITTVVDSYDD
EEEEEEEEEEECCCC		13.8623776212
63PhosphorylationVITTVVDSYDDSSSD
EEEEEEECCCCCCCC		20.8923776212
64PhosphorylationITTVVDSYDDSSSDD
EEEEEECCCCCCCCC		21.2123776212
67PhosphorylationVVDSYDDSSSDDEDE
EEECCCCCCCCCCCC		28.9223776212
68PhosphorylationVDSYDDSSSDDEDES
EECCCCCCCCCCCCC		44.7923776212
69PhosphorylationDSYDDSSSDDEDESH
ECCCCCCCCCCCCCC		53.7023776212
75PhosphorylationSSDDEDESHNRNVPY
CCCCCCCCCCCCCHH		38.0823776212
535PhosphorylationSNNTLKKSVSSPFMN
CCCCHHHHCCCCCCC		26.1623776212
537PhosphorylationNTLKKSVSSPFMNTA
CCHHHHCCCCCCCHH		39.1130291188
538PhosphorylationTLKKSVSSPFMNTAS
CHHHHCCCCCCCHHH		21.7223776212
543PhosphorylationVSSPFMNTASKMYSI
CCCCCCCHHHHCCCH		22.1123776212
545PhosphorylationSPFMNTASKMYSISE
CCCCCHHHHCCCHHH		18.8623776212
558PhosphorylationSEVRKHNTADSAWII
HHHHHCCCCCCEEEE		31.4025368622
561PhosphorylationRKHNTADSAWIIVHG
HHCCCCCCEEEEEEC		24.0425368622
584PhosphorylationLKDHPGGTDSILINA
HHCCCCCCCEEEEEC		32.2725368622
586PhosphorylationDHPGGTDSILINAGT
CCCCCCCEEEEECCC		21.0925368622
593PhosphorylationSILINAGTDCTEEFE
EEEEECCCCCHHHHH		26.0325368622
596PhosphorylationINAGTDCTEEFEAIH
EECCCCCHHHHHHHC		41.1625368622
604PhosphorylationEEFEAIHSDKAKKLL
HHHHHHCCHHHHHHH		34.3925368622
621PhosphorylationYRIGELITTGYDSSP
HCCHHHCCCCCCCCC		27.1323776212
622PhosphorylationRIGELITTGYDSSPN
CCHHHCCCCCCCCCC		27.1023776212
624PhosphorylationGELITTGYDSSPNVS
HHHCCCCCCCCCCEE		15.5723776212
626PhosphorylationLITTGYDSSPNVSVH
HCCCCCCCCCCEEEC		38.9323776212
627PhosphorylationITTGYDSSPNVSVHG
CCCCCCCCCCEEECC		20.0023776212
631PhosphorylationYDSSPNVSVHGASNF
CCCCCCEEECCCCCC		18.2923776212
636PhosphorylationNVSVHGASNFGPLLA
CEEECCCCCCCCCCC		36.9723776212
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NIA1_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NIA1_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NIA1_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MPK3_ARATHMPK3physical
20870959
MPK6_ARATHMPK6physical
20870959
CDC23_ARATHAPC8physical
21798944
14332_ARATHGRF2physical
25578809
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NIA1_ARATH

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-69, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory