| UniProt ID | NAGS_YEAST | |
|---|---|---|
| UniProt AC | P40360 | |
| Protein Name | Amino-acid acetyltransferase, mitochondrial | |
| Gene Name | ARG2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 574 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | N-acetylglutamate synthase involved in arginine biosynthesis.. | |
| Protein Sequence | MWRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLHKVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNIPHIDKFFILNNAGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLTKREPRSQNLLHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNPLVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNAAPSNSDAVLVTTVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSPKLDINKFKSIIDQSFKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLGISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLFYYGNPQYAKRALRDKKRLREFMRSVRDIKPSWENEKNIS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 19 | Phosphorylation | YDQPNASSKNLILSV CCCCCCCCCHHHHHH | 24.13 | 28889911 | |
| 25 | Phosphorylation | SSKNLILSVLNTTAT CCCHHHHHHHCCCCC | 19.98 | 19795423 | |
| 29 | Phosphorylation | LILSVLNTTATKREA HHHHHHCCCCCHHHH | 17.41 | 19795423 | |
| 30 | Phosphorylation | ILSVLNTTATKREAK HHHHHCCCCCHHHHH | 31.12 | 19823750 | |
| 32 | Phosphorylation | SVLNTTATKREAKDY HHHCCCCCHHHHHHH | 28.66 | 19823750 | |
| 37 | Acetylation | TATKREAKDYLSKYT CCCHHHHHHHHHHHC | 42.00 | 24489116 | |
| 62 | Acetylation | FFIRDLHKVAPAILS EEHHHHHHHHHHHHH | 47.60 | 24489116 | |
| 400 | Phosphorylation | GAKPSSNSPKLDINK CCCCCCCCCCCCHHH | 25.92 | 25704821 | |
| 427 | Acetylation | LDLHDYIKRINGKIA CCHHHHHHHHCCEEE | 40.78 | 24489116 | |
| 504 | Acetylation | RKDNVVNKWYFQRSV CCCCCCCHHHCCCCE | 31.49 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NAGS_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NAGS_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NAGS_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FEN1_YEAST | RAD27 | genetic | 20219942 | |
| MRC1_YEAST | MRC1 | genetic | 20219942 | |
| RIR1_YEAST | RNR1 | genetic | 20219942 | |
| CGS5_YEAST | CLB5 | genetic | 20219942 | |
| DPB4_YEAST | DPB4 | genetic | 20219942 | |
| DPB3_YEAST | DPB3 | genetic | 20219942 | |
| URA7_YEAST | URA7 | genetic | 20219942 | |
| FOLE_YEAST | MET7 | genetic | 20219942 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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