MRX9_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MRX9_YEAST
• UniProt AC: Q07349
• Protein Name: MIOREX complex component 9 {ECO:0000305|PubMed:25683707}
• Gene Name: MRX9 {ECO:0000303|PubMed:25683707}
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 420
• Subcellular Localization: Mitochondrion . Mitochondrion membrane ; Multi-pass membrane protein .
• Protein Description: Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression..
• Protein Sequence: MFKVPVGLASRTRELMNSVTLNSLNNGKGFNMYLPGILRAFPKPVPSAITSPAIPKYRGESFQFRKLSCISSNYCSTTHQFLSSLKSSTSRLVGKRAFHSSRRAEIKFIFSSKSPKNGNKPFVKVYKVSPFFIIFATASIFTFILTSTIVVIPLIFHFFFPLLIMFFFFKQFKKWQKNIFYKDVLTSLPKTKLKITLPTMRSLQLQPMVQSWKEISSRMGIPNEFAKGLNVDLVKQEETRKQFLSFLQKRVLESFTKNELGIRSYFLGDSVEKWIKESYDLELDIDNCRSELRKFQTFIFSSVRYKLYLDSMKNLPLNPSKKLEGKKHIADVYVIILDESFPAIMFNGGAYSKADFFKILQESETSNSSKTLNTIIAIKSVNTLLSKHFVITTNGDSGEFFSKYNISKINDKNTEYTLKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	RELMNSVTLNSLNNG HHHHHHCCHHHCCCC		27017623
363	Phosphorylation	FFKILQESETSNSSK HHHHHHHCCCCCCCC		28889911
365	Phosphorylation	KILQESETSNSSKTL HHHHHCCCCCCCCCH		28889911
369	Phosphorylation	ESETSNSSKTLNTII HCCCCCCCCCHHHHH		28889911
380	Phosphorylation	NTIIAIKSVNTLLSK HHHHHHHCHHHHHHC		28889911
383	Phosphorylation	IAIKSVNTLLSKHFV HHHHCHHHHHHCCEE		28889911
386	Phosphorylation	KSVNTLLSKHFVITT HCHHHHHHCCEEEEE		28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MRX9_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MRX9_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MRX9_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPB7_YEAST	RPB7	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
FDFT_YEAST	ERG9	genetic	27708008
ESS1_YEAST	ESS1	genetic	27708008
PRI2_YEAST	PRI2	genetic	27708008
PRS7_YEAST	RPT1	genetic	27708008
PROF_YEAST	PFY1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.