UniProt ID | MES1_SCHPO | |
---|---|---|
UniProt AC | P41005 | |
Protein Name | Protein mes1 | |
Gene Name | mes1 | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 101 | |
Subcellular Localization | Cytoplasm . Nucleus . | |
Protein Description | Specifically required for meiosis II (MII). Binds to slp1, an activator of the anapahase promoting complex/cyclcosome (APC/C), and counteracts its function in promoting proteolysis of cdc13. By suppressing the degradation of cdc13 at anaphase I this protein may help maintain a sufficient level of cdc2 kinase activity to complete MII.. | |
Protein Sequence | MVNTDNKENEPPNMEKAHMDSSNALYRVQRPLQRRPLQELSIELVKPSQTITVKKSKKSTNSSSYFAQLHAASGQNPPPSVHSSHKQPSKARSPNPLLSMR | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
---|---|---|---|---|---|---|
Oops, there are no PTM records of MES1_SCHPO !! |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MES1_SCHPO !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MES1_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MES1_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
SLP1_SCHPO | slp1 | genetic | 15791259 | |
SLP1_SCHPO | slp1 | physical | 15791259 | |
MFR1_SCHPO | mfr1 | genetic | 21389117 | |
MFR1_SCHPO | mfr1 | physical | 21389117 | |
SLP1_SCHPO | slp1 | physical | 21389117 | |
CG23_SCHPO | cdc13 | genetic | 15791259 | |
CG22_SCHPO | cig2 | genetic | 15791259 | |
MFR1_SCHPO | mfr1 | physical | 15791259 | |
MFR1_SCHPO | mfr1 | genetic | 23628763 | |
CUF2_SCHPO | cuf2 | genetic | 23628763 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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