MES1_SCHPO - dbPTM
MES1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MES1_SCHPO
UniProt AC P41005
Protein Name Protein mes1
Gene Name mes1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 101
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Specifically required for meiosis II (MII). Binds to slp1, an activator of the anapahase promoting complex/cyclcosome (APC/C), and counteracts its function in promoting proteolysis of cdc13. By suppressing the degradation of cdc13 at anaphase I this protein may help maintain a sufficient level of cdc2 kinase activity to complete MII..
Protein Sequence MVNTDNKENEPPNMEKAHMDSSNALYRVQRPLQRRPLQELSIELVKPSQTITVKKSKKSTNSSSYFAQLHAASGQNPPPSVHSSHKQPSKARSPNPLLSMR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of MES1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MES1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MES1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MES1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SLP1_SCHPOslp1genetic
15791259
SLP1_SCHPOslp1physical
15791259
MFR1_SCHPOmfr1genetic
21389117
MFR1_SCHPOmfr1physical
21389117
SLP1_SCHPOslp1physical
21389117
CG23_SCHPOcdc13genetic
15791259
CG22_SCHPOcig2genetic
15791259
MFR1_SCHPOmfr1physical
15791259
MFR1_SCHPOmfr1genetic
23628763
CUF2_SCHPOcuf2genetic
23628763

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MES1_SCHPO

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Related Literatures of Post-Translational Modification

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