dbPTM

MAP1B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MAP1B_MOUSE
UniProt AC	P14873
Protein Name	Microtubule-associated protein 1B
Gene Name	Map1b
Organism	Mus musculus (Mouse).
Sequence Length	2464
Subcellular Localization	Cytoplasm, cytoskeleton . Cytoplasm. Cell junction, synapse . Cell projection, dendritic spine . Colocalizes with DAPK1 in the microtubules and cortical actin fibers..
Protein Description	Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing (By similarity). Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Required for synaptic maturation..
Protein Sequence	MATVVVEATEPEPSGSIGNPAASTSPSLSHRFLDSKFYLLVVVGETVTEEHLRRAIGNIELGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEERSQGSTSNSDWMKNLISPDLGVVFLNVPENLKDPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIEPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAELILPNGQEVDIPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPPVKQVKLKQRADSRESLKPATKPVASKSVRKESKEETPEVTKTSQVEKTPKVESKEKVLVKKDKPVKTESKPSVTEKEVSSKEEQSPVKAEVAEKQATESKPKVTKDKVVKKEIKTKLEEKKEEKPKKEVVKKEDKTPLKKDEKPRKEEVKKEIKKEIKKEERKELKKEVKKETPLKDAKKEVKKEEKKEVKKEEKEPKKEIKKISKDIKKSTPLSDTKKPSALKPKVAKKEESTKKEPLAAGKLKDKGKVKVIKKEGKTTEAAATAVGTAATTAAVVAAAGIAASGPVKELEAERSLMSSPEDLTKDFEELKAEEIDVAKDIKPQLELIEDEEKLKETQPGEAYVIQKETEVSKGSAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEDNASGSASKHSPTEDDESAKAEADVHLKEKRESVVSGDDRAEEDMDDVLEKGEAEQSEEEGEEEDKAEDAREEGYEPDKTEAEDYVMAVADKAAEAGVTEEQYGYLGTSAKQPGIQSPSREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPAVASFNGLSEGSKTDATDGKDYNASASTISPPSSMEEDKFSKSALRDAYCSEEKELKASAELDIKDVSDERLSPAKSPSLSPSPPSPIEKTPLGERSVNFSLTPNEIKVSAEGEARSVSPGVTQAVVEEHCASPEEKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVTEKPQAVPVSFEFSEAKDENERASLSPMDEPVPDSESPVEKVLSPLRSPPLLGSESPYEDFLSADSKVLGRRSESPFEGKNGKQGFPDRESPVSDLTSTGLYQDKQEEKSTGFIPIKEDFGPEKKTSDVETMSSQSALALDERKLGGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEHSLAMDFSRQSPDHPTLGASVLHITENGPTEVDYSPSDIQDSSLSHKIPPTEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVVPPREMSLYASLASEKVQSLEGEKLSPKSDISPLTPRESSPLYSPGFSDSTSAAKETAAAHQASSSPPIDAATAEPYGFRSSMLFDTMQHHLALNRDLTTSSVEKDSGGKTPGDFNYAYQKPENAAGSPDEEDYDYESQEKTIRTHDVGGYYYEKTERTIKSPCDSGYSYETIEKTIKTPEDGGYTCEITEKTTRTPEEGGYSYEISEKTTRTPEVSGYTYEKTERSRRLLDDISNGYDDTEDGGHTLGDCSYSYETTEKITSFPESESYSYETSTKTTRSPDTSAYCYETMEKITKTPQASTYSYETSDRCYTTEKKSPSEARQDVDLCLVSSCEFKHPKTELSPSFINPNPLEWFAGEEPTEESEKPLTQSGGAPPPSGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTVTYKHMDPPPAPMQDRSPSPRHPDVSMVDPDALAVDQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKGDGKSKPLAASPKPGALKESSDKVSRVASPKKKESVEKATKTTTTPEVKATRGEEKDKETKNAANASASKSAKTATAGPGTTKTAKSSTVPPGLPVYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATVVVEAT ------CCEEEEEEC	22.02	-
9	Phosphorylation	ATVVVEATEPEPSGS CEEEEEECCCCCCCC	38.27	25619855
14	Phosphorylation	EATEPEPSGSIGNPA EECCCCCCCCCCCCC	43.44	25619855
16	Phosphorylation	TEPEPSGSIGNPAAS CCCCCCCCCCCCCCC	31.49	25619855
23	Phosphorylation	SIGNPAASTSPSLSH CCCCCCCCCCCCHHH	31.37	25619855
24	Phosphorylation	IGNPAASTSPSLSHR CCCCCCCCCCCHHHH	39.67	25619855
25	Phosphorylation	GNPAASTSPSLSHRF CCCCCCCCCCHHHHH	15.25	26824392
27	Phosphorylation	PAASTSPSLSHRFLD CCCCCCCCHHHHHHC	42.12	25619855
29	Phosphorylation	ASTSPSLSHRFLDSK CCCCCCHHHHHHCCC	19.56	25619855
35	Phosphorylation	LSHRFLDSKFYLLVV HHHHHHCCCEEEEEE	27.15	26643407
38	Phosphorylation	RFLDSKFYLLVVVGE HHHCCCEEEEEEECC	11.67	21454597
46	Phosphorylation	LLVVVGETVTEEHLR EEEEECCCCCHHHHH	27.14	21454597
91	Phosphorylation	SRHSARFSPEVPGQK HHHCCCCCCCCCCCE	18.01	27841257
197	Acetylation	CPEEGDWKNSNLDRH CCCCCCCCCCCCCCC	56.06	7970313
327	Ubiquitination	INSMLQRKIAELEEE HHHHHHHHHHHHHHH	33.05	22790023
336	Phosphorylation	AELEEERSQGSTSNS HHHHHHHHCCCCCCC	42.02	25521595
339	Phosphorylation	EEERSQGSTSNSDWM HHHHHCCCCCCCHHH	22.48	25521595
340	Phosphorylation	EERSQGSTSNSDWMK HHHHCCCCCCCHHHH	38.46	25521595
341	Phosphorylation	ERSQGSTSNSDWMKN HHHCCCCCCCHHHHH	35.71	25521595
343	Phosphorylation	SQGSTSNSDWMKNLI HCCCCCCCHHHHHHC	32.20	25521595
366	Ubiquitination	LNVPENLKDPEPNIK ECCCHHCCCCCCCCC	80.81	22790023
394	Ubiquitination	YLNKLSMKPEPLFRS HHHHHCCCCCCCCCC	42.74	22790023
401	Phosphorylation	KPEPLFRSVGNTIEP CCCCCCCCCCCCCCE	27.35	22817900
405	Phosphorylation	LFRSVGNTIEPVILF CCCCCCCCCCEEHHE	22.31	29899451
429	Ubiquitination	MYVLNPVKSSKEMQY EEEECCCCCHHHHHH	50.71	22790023
432	Ubiquitination	LNPVKSSKEMQYFMQ ECCCCCHHHHHHHHH	65.38	22790023
436	Phosphorylation	KSSKEMQYFMQQWTG CCHHHHHHHHHHHCC	10.33	26643407
446	Ubiquitination	QQWTGTNKDKAELIL HHHCCCCCCCCEEEC	61.52	22790023
494	Phosphorylation	VLFPGNSTQYNILEG HHCCCCHHHHCHHHH	38.79	25521595
496	Phosphorylation	FPGNSTQYNILEGLE CCCCHHHHCHHHHHH	12.31	25521595
504	Ubiquitination	NILEGLEKLKHLDFL CHHHHHHHHCCCHHH	68.80	22790023
519	Ubiquitination	KQPLATQKDLTGQVP CCCCCCCCCCCCCCC	50.80	22790023
527	Phosphorylation	DLTGQVPTPPVKQVK CCCCCCCCCCCCCCE	41.17	25521595
541	Phosphorylation	KLKQRADSRESLKPA EECCCCCCHHHCCCC	36.64	18388127
544	Phosphorylation	QRADSRESLKPATKP CCCCCHHHCCCCCCC	40.35	18388127
549	Phosphorylation	RESLKPATKPVASKS HHHCCCCCCCCCCHH	44.39	25777480
556	Phosphorylation	TKPVASKSVRKESKE CCCCCCHHHCHHCCC	25.34	23684622
561	Phosphorylation	SKSVRKESKEETPEV CHHHCHHCCCCCCCC	48.69	26824392
565	Phosphorylation	RKESKEETPEVTKTS CHHCCCCCCCCCCCC	26.32	27742792
569	Phosphorylation	KEETPEVTKTSQVEK CCCCCCCCCCCCCCC	27.26	23335269
571	Phosphorylation	ETPEVTKTSQVEKTP CCCCCCCCCCCCCCC	18.28	22817900
572	Phosphorylation	TPEVTKTSQVEKTPK CCCCCCCCCCCCCCC	33.51	21183079
577	Phosphorylation	KTSQVEKTPKVESKE CCCCCCCCCCCCCCC	18.16	22817900
582	Phosphorylation	EKTPKVESKEKVLVK CCCCCCCCCCEEEEE	49.45	22817900
598	Phosphorylation	DKPVKTESKPSVTEK CCCCCCCCCCCCCHH	55.91	25338131
601	Phosphorylation	VKTESKPSVTEKEVS CCCCCCCCCCHHHCC	45.46	27841257
608	Phosphorylation	SVTEKEVSSKEEQSP CCCHHHCCCHHHCCC	36.46	25521595
609	Phosphorylation	VTEKEVSSKEEQSPV CCHHHCCCHHHCCCH	49.62	25619855
614	Phosphorylation	VSSKEEQSPVKAEVA CCCHHHCCCHHHHHH	34.63	25521595
665	Phosphorylation	VVKKEDKTPLKKDEK HCCCCCCCCCCCCCC	46.29	28066266
702	Phosphorylation	KKEVKKETPLKDAKK HHHHHHHCCHHHHHH	42.68	18779572
716	Acetylation	KEVKKEEKKEVKKEE HHHHHHHHHHHHHHH	56.15	7625209
734	Phosphorylation	KKEIKKISKDIKKST HHHHHHHHHHHHHCC	32.91	18779572
740	Phosphorylation	ISKDIKKSTPLSDTK HHHHHHHCCCCCCCC	30.20	28066266
741	Phosphorylation	SKDIKKSTPLSDTKK HHHHHHCCCCCCCCC	36.81	28066266
744	Phosphorylation	IKKSTPLSDTKKPSA HHHCCCCCCCCCCCC	44.42	28066266
746	Phosphorylation	KSTPLSDTKKPSALK HCCCCCCCCCCCCCC	37.28	28066266
788	Phosphorylation	VIKKEGKTTEAAATA EEEECCCCHHHHHHH	40.50	25777480
789	Phosphorylation	IKKEGKTTEAAATAV EEECCCCHHHHHHHH	27.41	25777480
794	O-linked_Glycosylation	KTTEAAATAVGTAAT CCHHHHHHHHHHHHH	19.70	55412575
794	Phosphorylation	KTTEAAATAVGTAAT CCHHHHHHHHHHHHH	19.70	25777480
798	Phosphorylation	AAATAVGTAATTAAV HHHHHHHHHHHHHHH	13.40	25777480
801	Phosphorylation	TAVGTAATTAAVVAA HHHHHHHHHHHHHHH	17.95	25777480
802	Phosphorylation	AVGTAATTAAVVAAA HHHHHHHHHHHHHHH	14.11	25777480
814	Phosphorylation	AAAGIAASGPVKELE HHHHHHHCCCHHHHH	34.31	25777480
825	Phosphorylation	KELEAERSLMSSPED HHHHHHHHHCCCHHH	21.67	18388127
828	Phosphorylation	EAERSLMSSPEDLTK HHHHHHCCCHHHHHH	48.29	25521595
829	Phosphorylation	AERSLMSSPEDLTKD HHHHHCCCHHHHHHC	20.53	25521595
834	Phosphorylation	MSSPEDLTKDFEELK CCCHHHHHHCHHHHH	40.67	24925903
841	Ubiquitination	TKDFEELKAEEIDVA HHCHHHHHHHHCCHH	57.96	22790023
852	Ubiquitination	IDVAKDIKPQLELIE CCHHHHCHHHHHHHC	36.52	22790023
863	Ubiquitination	ELIEDEEKLKETQPG HHHCCHHHHHHCCCC	63.91	22790023
865	Ubiquitination	IEDEEKLKETQPGEA HCCHHHHHHCCCCCE	70.55	22790023
873	Phosphorylation	ETQPGEAYVIQKETE HCCCCCEEEEEEEEE	8.19	29514104
877	Ubiquitination	GEAYVIQKETEVSKG CCEEEEEEEEEECCC	56.32	22790023
879	Phosphorylation	AYVIQKETEVSKGSA EEEEEEEEEECCCCC	49.04	19060867
882	Phosphorylation	IQKETEVSKGSAESP EEEEEEECCCCCCCC	25.68	19060867
885	Phosphorylation	ETEVSKGSAESPDEG EEEECCCCCCCCCCC	32.38	24925903
888	Phosphorylation	VSKGSAESPDEGITT ECCCCCCCCCCCCCC	37.05	25521595
894	Phosphorylation	ESPDEGITTTEGEGE CCCCCCCCCCCCCCC	38.22	21659605
895	Phosphorylation	SPDEGITTTEGEGEC CCCCCCCCCCCCCCC	22.41	24925903
896	Phosphorylation	PDEGITTTEGEGECE CCCCCCCCCCCCCCC	33.09	25521595
905	Phosphorylation	GEGECEQTPEELEPV CCCCCCCCHHHCCCC	15.46	25521595
933	Phosphorylation	EGAGFEESSETGDYE CCCCCCCCCCCCCHH	26.69	25521595
934	Phosphorylation	GAGFEESSETGDYEE CCCCCCCCCCCCHHH	42.32	25521595
936	Phosphorylation	GFEESSETGDYEEKA CCCCCCCCCCHHHHH	36.98	25521595
939	Phosphorylation	ESSETGDYEEKAETE CCCCCCCHHHHHCCC	27.60	25619855
945	Phosphorylation	DYEEKAETEEAEEPE CHHHHHCCCCCCCCC	43.94	25521595
960	Phosphorylation	EDGEDNASGSASKHS CCCCCCCCCCCCCCC	39.26	25521595
962	Phosphorylation	GEDNASGSASKHSPT CCCCCCCCCCCCCCC	27.20	25619855
964	Phosphorylation	DNASGSASKHSPTED CCCCCCCCCCCCCCC	32.38	25619855
967	Phosphorylation	SGSASKHSPTEDDES CCCCCCCCCCCCCHH	36.93	25521595
969	Phosphorylation	SASKHSPTEDDESAK CCCCCCCCCCCHHHH	55.87	25521595
974	Phosphorylation	SPTEDDESAKAEADV CCCCCCHHHHHHHHC	41.90	25521595
989	Phosphorylation	HLKEKRESVVSGDDR HHHHHHHHHHCCCCC	31.67	25521595
992	Phosphorylation	EKRESVVSGDDRAEE HHHHHHHCCCCCCHH	34.06	25521595
1013	Phosphorylation	EKGEAEQSEEEGEEE HHHHHHHCHHCCCHH	38.18	25521595
1031	Phosphorylation	EDAREEGYEPDKTEA HHHHHHCCCCCCCCH	27.80	29899451
1036	Phosphorylation	EGYEPDKTEAEDYVM HCCCCCCCCHHHHHH	48.05	-
1073	Phosphorylation	AKQPGIQSPSREPAS CCCCCCCCCCCCCCH	23.95	25521595
1075	Phosphorylation	QPGIQSPSREPASSI CCCCCCCCCCCCHHC	55.30	30372032
1080	Phosphorylation	SPSREPASSIHDETL CCCCCCCHHCCCCCC	40.31	20415495
1086	Phosphorylation	ASSIHDETLPGGSES CHHCCCCCCCCCCCC	44.29	28066266
1091	Phosphorylation	DETLPGGSESEATAS CCCCCCCCCCCCCCC	43.81	28066266
1093	Phosphorylation	TLPGGSESEATASDE CCCCCCCCCCCCCCC	33.94	28066266
1096	Phosphorylation	GGSESEATASDEENR CCCCCCCCCCCCCCC	23.73	28066266
1098	Phosphorylation	SESEATASDEENRED CCCCCCCCCCCCCCC	41.00	28066266
1141	Phosphorylation	STPRDVMSDETNNEE CCCHHHCCCCCCCCC	31.95	25521595
1144	Phosphorylation	RDVMSDETNNEETES HHHCCCCCCCCCCCC	48.62	25619855
1149	Phosphorylation	DETNNEETESPSQEF CCCCCCCCCCCCHHH	35.27	25521595
1151	Phosphorylation	TNNEETESPSQEFVN CCCCCCCCCCHHHHH	36.95	25521595
1153	Phosphorylation	NEETESPSQEFVNIT CCCCCCCCHHHHHHH	52.18	25521595
1160	Phosphorylation	SQEFVNITKYESSLY CHHHHHHHHHCHHCC	23.52	25619855
1167	Phosphorylation	TKYESSLYSQEYSKP HHHCHHCCCCCCCCC	15.40	-
1168	Phosphorylation	KYESSLYSQEYSKPA HHCHHCCCCCCCCCC	23.10	27841257
1178	Phosphorylation	YSKPAVASFNGLSEG CCCCCEEECCCCCCC	16.79	27841257
1183	Phosphorylation	VASFNGLSEGSKTDA EEECCCCCCCCCCCC	41.11	22817900
1186	Phosphorylation	FNGLSEGSKTDATDG CCCCCCCCCCCCCCC	28.47	22817900
1188	Phosphorylation	GLSEGSKTDATDGKD CCCCCCCCCCCCCCC	32.34	25777480
1191	Phosphorylation	EGSKTDATDGKDYNA CCCCCCCCCCCCCCC	48.36	27742792
1196	Phosphorylation	DATDGKDYNASASTI CCCCCCCCCCCCCCC	19.00	24925903
1199	Phosphorylation	DGKDYNASASTISPP CCCCCCCCCCCCCCC	21.08	25619855
1201	Phosphorylation	KDYNASASTISPPSS CCCCCCCCCCCCCHH	24.63	25619855
1202	Phosphorylation	DYNASASTISPPSSM CCCCCCCCCCCCHHH	25.78	25619855
1204	Phosphorylation	NASASTISPPSSMEE CCCCCCCCCCHHHCC	30.74	25521595
1207	Phosphorylation	ASTISPPSSMEEDKF CCCCCCCHHHCCCCC	45.78	25521595
1208	Phosphorylation	STISPPSSMEEDKFS CCCCCCHHHCCCCCC	35.67	25521595
1215	Phosphorylation	SMEEDKFSKSALRDA HHCCCCCCHHHHHHH	31.29	25619855
1217	Phosphorylation	EEDKFSKSALRDAYC CCCCCCHHHHHHHHC	31.19	29899451
1223	Phosphorylation	KSALRDAYCSEEKEL HHHHHHHHCCCHHHH	10.78	29899451
1225	Phosphorylation	ALRDAYCSEEKELKA HHHHHHCCCHHHHHH	35.79	22817900
1233	Phosphorylation	EEKELKASAELDIKD CHHHHHHCEECCCCC	22.23	25521595
1242	Phosphorylation	ELDIKDVSDERLSPA ECCCCCCCCCCCCCC	43.84	25521595
1247	Phosphorylation	DVSDERLSPAKSPSL CCCCCCCCCCCCCCC	29.09	25521595
1251	Phosphorylation	ERLSPAKSPSLSPSP CCCCCCCCCCCCCCC	23.10	25521595
1253	Phosphorylation	LSPAKSPSLSPSPPS CCCCCCCCCCCCCCC	48.87	25521595
1255	Phosphorylation	PAKSPSLSPSPPSPI CCCCCCCCCCCCCCC	27.89	25521595
1257	Phosphorylation	KSPSLSPSPPSPIEK CCCCCCCCCCCCCCC	46.17	25521595
1260	Phosphorylation	SLSPSPPSPIEKTPL CCCCCCCCCCCCCCC	41.72	18388127
1265	Phosphorylation	PPSPIEKTPLGERSV CCCCCCCCCCCCCEE	15.79	22942356
1271	Phosphorylation	KTPLGERSVNFSLTP CCCCCCCEEEEECCC	19.67	23527152
1275	Phosphorylation	GERSVNFSLTPNEIK CCCEEEEECCCCEEE	26.57	18779572
1277	Phosphorylation	RSVNFSLTPNEIKVS CEEEEECCCCEEEEC	23.91	23527152
1284	Phosphorylation	TPNEIKVSAEGEARS CCCEEEECCCCCCCC	18.66	26643407
1291	Phosphorylation	SAEGEARSVSPGVTQ CCCCCCCCCCCCCHH	33.71	24925903
1293	Phosphorylation	EGEARSVSPGVTQAV CCCCCCCCCCCHHHH	19.72	25521595
1297	Phosphorylation	RSVSPGVTQAVVEEH CCCCCCCHHHHHHHH	19.41	24925903
1307	Phosphorylation	VVEEHCASPEEKTLE HHHHHCCCCCCCCEE	37.93	25521595
1312	Phosphorylation	CASPEEKTLEVVSPS CCCCCCCCEEEECCC	31.28	25619855
1317	Phosphorylation	EKTLEVVSPSQSVTG CCCEEEECCCHHCCC	24.82	25521595
1319	Phosphorylation	TLEVVSPSQSVTGSA CEEEECCCHHCCCCC	27.81	24925903
1321	Phosphorylation	EVVSPSQSVTGSAGH EEECCCHHCCCCCCC	26.45	24925903
1323	Phosphorylation	VSPSQSVTGSAGHTP ECCCHHCCCCCCCCC	30.57	24925903
1325	Phosphorylation	PSQSVTGSAGHTPYY CCHHCCCCCCCCCCC	23.01	24925903
1329	Phosphorylation	VTGSAGHTPYYQSPT CCCCCCCCCCCCCCC	16.45	24925903
1331	Phosphorylation	GSAGHTPYYQSPTDE CCCCCCCCCCCCCCC	18.45	24925903
1332	Phosphorylation	SAGHTPYYQSPTDEK CCCCCCCCCCCCCCC	12.06	24925903
1334	Phosphorylation	GHTPYYQSPTDEKSS CCCCCCCCCCCCCCC	17.41	18388127
1336	Phosphorylation	TPYYQSPTDEKSSHL CCCCCCCCCCCCCCC	63.14	25619855
1340	Phosphorylation	QSPTDEKSSHLPTEV CCCCCCCCCCCCCCC	22.42	25521595
1341	Phosphorylation	SPTDEKSSHLPTEVT CCCCCCCCCCCCCCC	39.86	28464351
1345	Phosphorylation	EKSSHLPTEVTEKPQ CCCCCCCCCCCCCCC	49.82	29899451
1348	Phosphorylation	SHLPTEVTEKPQAVP CCCCCCCCCCCCCEE	31.87	29899451
1357	Phosphorylation	KPQAVPVSFEFSEAK CCCCEEEEEECCCCC	17.00	29899451
1361	Phosphorylation	VPVSFEFSEAKDENE EEEEEECCCCCCCCC	29.46	27841257
1371	Phosphorylation	KDENERASLSPMDEP CCCCCCCCCCCCCCC	35.28	25521595
1373	Phosphorylation	ENERASLSPMDEPVP CCCCCCCCCCCCCCC	18.71	25521595
1382	Phosphorylation	MDEPVPDSESPVEKV CCCCCCCCCCHHHHH	33.63	25521595
1384	Phosphorylation	EPVPDSESPVEKVLS CCCCCCCCHHHHHCC	37.89	25521595
1391	Phosphorylation	SPVEKVLSPLRSPPL CHHHHHCCCCCCCCC	25.52	25521595
1395	Phosphorylation	KVLSPLRSPPLLGSE HHCCCCCCCCCCCCC	38.25	18388127
1401	Phosphorylation	RSPPLLGSESPYEDF CCCCCCCCCCCHHHH	34.57	25521595
1403	Phosphorylation	PPLLGSESPYEDFLS CCCCCCCCCHHHHHC	34.18	24925903
1405	Phosphorylation	LLGSESPYEDFLSAD CCCCCCCHHHHHCCC	37.09	24925903
1410	Phosphorylation	SPYEDFLSADSKVLG CCHHHHHCCCCCHHC	29.98	24925903
1413	Phosphorylation	EDFLSADSKVLGRRS HHHHCCCCCHHCCCC	25.12	25619855
1420	Phosphorylation	SKVLGRRSESPFEGK CCHHCCCCCCCCCCC	40.85	27087446
1422	Phosphorylation	VLGRRSESPFEGKNG HHCCCCCCCCCCCCC	35.81	25521595
1438	Phosphorylation	QGFPDRESPVSDLTS CCCCCCCCCCCHHHH	31.34	25521595
1441	Phosphorylation	PDRESPVSDLTSTGL CCCCCCCCHHHHCCC	30.22	25521595
1444	Phosphorylation	ESPVSDLTSTGLYQD CCCCCHHHHCCCCCC	29.27	24925903
1445	Phosphorylation	SPVSDLTSTGLYQDK CCCCHHHHCCCCCCC	27.98	25619855
1446	Phosphorylation	PVSDLTSTGLYQDKQ CCCHHHHCCCCCCCC	26.43	25619855
1449	Phosphorylation	DLTSTGLYQDKQEEK HHHHCCCCCCCCCCC	18.93	25619855
1457	Phosphorylation	QDKQEEKSTGFIPIK CCCCCCCCCCEEECC	36.72	28066266
1458	Phosphorylation	DKQEEKSTGFIPIKE CCCCCCCCCEEECCC	47.37	28066266
1464	Ubiquitination	STGFIPIKEDFGPEK CCCEEECCCCCCCCC	45.97	22790023
1473	Phosphorylation	DFGPEKKTSDVETMS CCCCCCCCCCHHHHH	41.02	28066266
1474	Phosphorylation	FGPEKKTSDVETMSS CCCCCCCCCHHHHHH	48.84	28066266
1478	Phosphorylation	KKTSDVETMSSQSAL CCCCCHHHHHHHHHH	23.38	22817900
1480	Phosphorylation	TSDVETMSSQSALAL CCCHHHHHHHHHHHH	32.42	28066266
1481	Phosphorylation	SDVETMSSQSALALD CCHHHHHHHHHHHHC	19.82	28066266
1483	Phosphorylation	VETMSSQSALALDER HHHHHHHHHHHHCHH	27.48	28066266
1497	Phosphorylation	RKLGGDVSPTQIDVS HHHCCCCCCCEECHH	27.28	27087446
1499	Phosphorylation	LGGDVSPTQIDVSQF HCCCCCCCEECHHHH	30.56	25521595
1504	Phosphorylation	SPTQIDVSQFGSFKE CCCEECHHHHCCCCC	18.95	25619855
1508	Phosphorylation	IDVSQFGSFKEDTKM ECHHHHCCCCCCCCC	34.14	25521595
1513	Phosphorylation	FGSFKEDTKMSISEG HCCCCCCCCCEECCC	29.73	25619855
1516	Phosphorylation	FKEDTKMSISEGTVS CCCCCCCEECCCCCC	25.23	25521595
1518	Phosphorylation	EDTKMSISEGTVSDK CCCCCEECCCCCCCC	23.75	22324799
1521	Phosphorylation	KMSISEGTVSDKSAT CCEECCCCCCCCCCC	16.88	25521595
1523	Phosphorylation	SISEGTVSDKSATPV EECCCCCCCCCCCCC	38.88	25521595
1539	Phosphorylation	EGVAEDTYSHMEGVA CCCCCCHHHCCCCCE	14.65	22817900
1614	Phosphorylation	EECPRPMSISPPDFS CCCCCCCCCCCCCCC	23.69	25521595
1616	Phosphorylation	CPRPMSISPPDFSPK CCCCCCCCCCCCCCC	24.07	25521595
1621	Phosphorylation	SISPPDFSPKTAKSR CCCCCCCCCCCCCCC	32.63	25521595
1627	Phosphorylation	FSPKTAKSRTPVQDH CCCCCCCCCCCCCCC	38.63	25521595
1629	Phosphorylation	PKTAKSRTPVQDHRS CCCCCCCCCCCCCCC	34.60	25521595
1636	Phosphorylation	TPVQDHRSEQSSMSI CCCCCCCCCCCCCEE	36.25	23649490
1639	Phosphorylation	QDHRSEQSSMSIEFG CCCCCCCCCCEEECC	24.77	29899451
1640	Phosphorylation	DHRSEQSSMSIEFGQ CCCCCCCCCEEECCC	19.08	24925903
1642	Phosphorylation	RSEQSSMSIEFGQES CCCCCCCEEECCCCC	22.40	24925903
1649	Phosphorylation	SIEFGQESPEHSLAM EEECCCCCCCCCEEC	27.92	25521595
1653	Phosphorylation	GQESPEHSLAMDFSR CCCCCCCCEECCCCC	19.03	25521595
1659	Phosphorylation	HSLAMDFSRQSPDHP CCEECCCCCCCCCCC	25.75	25293948
1662	Phosphorylation	AMDFSRQSPDHPTLG ECCCCCCCCCCCCCC	31.05	21082442
1667	Phosphorylation	RQSPDHPTLGASVLH CCCCCCCCCCCEEEE	34.11	26160508
1671	Phosphorylation	DHPTLGASVLHITEN CCCCCCCEEEEECCC	24.34	26160508
1676	Phosphorylation	GASVLHITENGPTEV CCEEEEECCCCCCCC	16.79	26160508
1681	Phosphorylation	HITENGPTEVDYSPS EECCCCCCCCCCCHH	50.46	26160508
1685	Phosphorylation	NGPTEVDYSPSDIQD CCCCCCCCCHHHCCC	27.88	21183079
1686	Phosphorylation	GPTEVDYSPSDIQDS CCCCCCCCHHHCCCC	17.29	26824392
1688	Phosphorylation	TEVDYSPSDIQDSSL CCCCCCHHHCCCCCC	41.21	19060867
1693	Phosphorylation	SPSDIQDSSLSHKIP CHHHCCCCCCCCCCC	19.46	19060867
1694	Phosphorylation	PSDIQDSSLSHKIPP HHHCCCCCCCCCCCC	42.03	19060867
1696	Phosphorylation	DIQDSSLSHKIPPTE HCCCCCCCCCCCCCC	25.36	19060867
1708	Phosphorylation	PTEEPSYTQDNDLSE CCCCCCCCCCCCHHH	33.51	23649490
1735	Phosphorylation	TSSAHTPSQIASPLQ CCCCCCHHHCCCCCC	35.06	23649490
1739	Phosphorylation	HTPSQIASPLQEDTL CCHHHCCCCCCCCCH	27.98	23649490
1756	Phosphorylation	VVPPREMSLYASLAS CCCHHHHHHHHHHHH	17.30	28066266
1758	Phosphorylation	PPREMSLYASLASEK CHHHHHHHHHHHHHH	6.19	28066266
1760	Phosphorylation	REMSLYASLASEKVQ HHHHHHHHHHHHHHH	15.77	28066266
1763	Phosphorylation	SLYASLASEKVQSLE HHHHHHHHHHHHHCC	43.15	28066266
1768	Phosphorylation	LASEKVQSLEGEKLS HHHHHHHHCCCCCCC	31.23	25521595
1775	Phosphorylation	SLEGEKLSPKSDISP HCCCCCCCCCCCCCC	41.15	25521595
1777	Ubiquitination	EGEKLSPKSDISPLT CCCCCCCCCCCCCCC	58.34	22790023
1778	Phosphorylation	GEKLSPKSDISPLTP CCCCCCCCCCCCCCC	43.49	25521595
1781	Phosphorylation	LSPKSDISPLTPRES CCCCCCCCCCCCCCC	20.88	25521595
1784	Phosphorylation	KSDISPLTPRESSPL CCCCCCCCCCCCCCC	24.55	25521595
1788	Phosphorylation	SPLTPRESSPLYSPG CCCCCCCCCCCCCCC	38.24	25521595
1789	Phosphorylation	PLTPRESSPLYSPGF CCCCCCCCCCCCCCC	17.74	18388127
1792	Phosphorylation	PRESSPLYSPGFSDS CCCCCCCCCCCCCCC	19.06	25521595
1793	Phosphorylation	RESSPLYSPGFSDST CCCCCCCCCCCCCCC	26.65	25521595
1797	Phosphorylation	PLYSPGFSDSTSAAK CCCCCCCCCCCHHHH	36.24	24925903
1799	Phosphorylation	YSPGFSDSTSAAKET CCCCCCCCCHHHHHH	24.06	25619855
1800	Phosphorylation	SPGFSDSTSAAKETA CCCCCCCCHHHHHHH	27.63	24925903
1801	Phosphorylation	PGFSDSTSAAKETAA CCCCCCCHHHHHHHH	30.13	24925903
1806	Phosphorylation	STSAAKETAAAHQAS CCHHHHHHHHHHHHH	22.38	24925903
1813	Phosphorylation	TAAAHQASSSPPIDA HHHHHHHHCCCCCCH	25.44	25521595
1814	Phosphorylation	AAAHQASSSPPIDAA HHHHHHHCCCCCCHH	50.29	25521595
1815	Phosphorylation	AAHQASSSPPIDAAT HHHHHHCCCCCCHHH	32.00	25521595
1822	Phosphorylation	SPPIDAATAEPYGFR CCCCCHHHCCCCCCC	33.02	25619855
1826	Phosphorylation	DAATAEPYGFRSSML CHHHCCCCCCCHHHH	22.02	25619855
1830	Phosphorylation	AEPYGFRSSMLFDTM CCCCCCCHHHHHHHH	20.17	25177544
1831	Phosphorylation	EPYGFRSSMLFDTMQ CCCCCCHHHHHHHHH	18.43	24899341
1836	Phosphorylation	RSSMLFDTMQHHLAL CHHHHHHHHHHHHHH	16.05	29895711
1849	Phosphorylation	ALNRDLTTSSVEKDS HHCCCCCCCEEEECC	26.71	28066266
1850	Phosphorylation	LNRDLTTSSVEKDSG HCCCCCCCEEEECCC	27.44	25521595
1851	Phosphorylation	NRDLTTSSVEKDSGG CCCCCCCEEEECCCC	32.00	22324799
1856	Phosphorylation	TSSVEKDSGGKTPGD CCEEEECCCCCCCCC	61.59	30372032
1860	Phosphorylation	EKDSGGKTPGDFNYA EECCCCCCCCCCCCC	35.46	24925903
1866	Phosphorylation	KTPGDFNYAYQKPEN CCCCCCCCCCCCCCC	13.48	25619855
1868	Phosphorylation	PGDFNYAYQKPENAA CCCCCCCCCCCCCCC	13.50	25619855
1877	Phosphorylation	KPENAAGSPDEEDYD CCCCCCCCCCHHHCC	25.17	25521595
1883	Phosphorylation	GSPDEEDYDYESQEK CCCCHHHCCHHHHCC	24.57	25619855
1885	Phosphorylation	PDEEDYDYESQEKTI CCHHHCCHHHHCCEE	15.96	25619855
1887	Phosphorylation	EEDYDYESQEKTIRT HHHCCHHHHCCEEEE	37.09	25619855
1900	Phosphorylation	RTHDVGGYYYEKTER EECCCCCCEEEECCC	9.28	-
1901	Phosphorylation	THDVGGYYYEKTERT ECCCCCCEEEECCCE	14.39	18563927
1902	Phosphorylation	HDVGGYYYEKTERTI CCCCCCEEEECCCEE	11.49	29514104
1904	Ubiquitination	VGGYYYEKTERTIKS CCCCEEEECCCEECC	39.29	22790023
1908	Phosphorylation	YYEKTERTIKSPCDS EEEECCCEECCCCCC	26.90	25619855
1910	Ubiquitination	EKTERTIKSPCDSGY EECCCEECCCCCCCC	47.97	-
1911	Phosphorylation	KTERTIKSPCDSGYS ECCCEECCCCCCCCC	27.23	25521595
1913	S-nitrosocysteine	ERTIKSPCDSGYSYE CCEECCCCCCCCCHH	9.32	-
1913	S-nitrosylation	ERTIKSPCDSGYSYE CCEECCCCCCCCCHH	9.32	22178444
1915	Phosphorylation	TIKSPCDSGYSYETI EECCCCCCCCCHHHH	46.47	25619855
1917	Phosphorylation	KSPCDSGYSYETIEK CCCCCCCCCHHHHHH	16.42	25619855
1918	Phosphorylation	SPCDSGYSYETIEKT CCCCCCCCHHHHHHE	21.73	25619855
1919	Phosphorylation	PCDSGYSYETIEKTI CCCCCCCHHHHHHEE	14.49	25619855
1921	Phosphorylation	DSGYSYETIEKTIKT CCCCCHHHHHHEECC	26.63	25619855
1925	Phosphorylation	SYETIEKTIKTPEDG CHHHHHHEECCCCCC	18.21	23335269
1928	Phosphorylation	TIEKTIKTPEDGGYT HHHHEECCCCCCCCE	28.23	25521595
1934	Phosphorylation	KTPEDGGYTCEITEK CCCCCCCCEEEEEEC	17.47	22324799
1936	S-nitrosocysteine	PEDGGYTCEITEKTT CCCCCCEEEEEECCE	2.40	-
1936	S-nitrosylation	PEDGGYTCEITEKTT CCCCCCEEEEEECCE	2.40	22178444
1941	Ubiquitination	YTCEITEKTTRTPEE CEEEEEECCEECCCC	46.69	22790023
1942	Phosphorylation	TCEITEKTTRTPEEG EEEEEECCEECCCCC	18.44	24925903
1943	Phosphorylation	CEITEKTTRTPEEGG EEEEECCEECCCCCC	43.54	24925903
1945	Phosphorylation	ITEKTTRTPEEGGYS EEECCEECCCCCCEE	32.72	25521595
1951	Phosphorylation	RTPEEGGYSYEISEK ECCCCCCEEEEEECC	20.95	25619855
1952	Phosphorylation	TPEEGGYSYEISEKT CCCCCCEEEEEECCC	21.40	25619855
1953	Phosphorylation	PEEGGYSYEISEKTT CCCCCEEEEEECCCC	14.59	25619855
1956	Phosphorylation	GGYSYEISEKTTRTP CCEEEEEECCCCCCC	22.54	25619855
1958	Ubiquitination	YSYEISEKTTRTPEV EEEEEECCCCCCCCC	48.70	22790023
1959	Phosphorylation	SYEISEKTTRTPEVS EEEEECCCCCCCCCC	19.91	24899341
1960	Phosphorylation	YEISEKTTRTPEVSG EEEECCCCCCCCCCC	43.54	24453211
1962	Phosphorylation	ISEKTTRTPEVSGYT EECCCCCCCCCCCCE	23.00	21659605
1966	Phosphorylation	TTRTPEVSGYTYEKT CCCCCCCCCCEEECC	25.15	21659605
1968	Phosphorylation	RTPEVSGYTYEKTER CCCCCCCCEEECCHH	9.91	26643407
1969	Phosphorylation	TPEVSGYTYEKTERS CCCCCCCEEECCHHH	28.82	26643407
1970	Phosphorylation	PEVSGYTYEKTERSR CCCCCCEEECCHHHH	13.62	22817900
1972	Acetylation	VSGYTYEKTERSRRL CCCCEEECCHHHHHH	45.32	23806337
1972	Ubiquitination	VSGYTYEKTERSRRL CCCCEEECCHHHHHH	45.32	22790023
1984	Phosphorylation	RRLLDDISNGYDDTE HHHHHHHHCCCCCCC	31.06	29899451
1987	Phosphorylation	LDDISNGYDDTEDGG HHHHHCCCCCCCCCC	18.20	29899451
1990	Phosphorylation	ISNGYDDTEDGGHTL HHCCCCCCCCCCCCC	32.83	24759943
1996	Phosphorylation	DTEDGGHTLGDCSYS CCCCCCCCCCCCCEE	35.39	22006019
2003	Phosphorylation	TLGDCSYSYETTEKI CCCCCCEEEECCCCE	10.53	-
2011	Phosphorylation	YETTEKITSFPESES EECCCCEECCCCCCC	35.07	28066266
2012	Phosphorylation	ETTEKITSFPESESY ECCCCEECCCCCCCC	42.13	30372032
2016	Phosphorylation	KITSFPESESYSYET CEECCCCCCCCEEEC	31.89	28066266
2018	Phosphorylation	TSFPESESYSYETST ECCCCCCCCEEECCC	28.76	28066266
2020	Phosphorylation	FPESESYSYETSTKT CCCCCCCEEECCCCC	26.27	28066266
2021	Phosphorylation	PESESYSYETSTKTT CCCCCCEEECCCCCC	18.26	29899451
2023	Phosphorylation	SESYSYETSTKTTRS CCCCEEECCCCCCCC	33.20	28066266
2024	Phosphorylation	ESYSYETSTKTTRSP CCCEEECCCCCCCCC	18.90	28066266
2025	Phosphorylation	SYSYETSTKTTRSPD CCEEECCCCCCCCCC	39.57	28066266
2026	Ubiquitination	YSYETSTKTTRSPDT CEEECCCCCCCCCCC	47.90	22790023
2027	O-linked_Glycosylation	SYETSTKTTRSPDTS EEECCCCCCCCCCCC	27.77	28528544
2027	Phosphorylation	SYETSTKTTRSPDTS EEECCCCCCCCCCCC	27.77	25521595
2028	Phosphorylation	YETSTKTTRSPDTSA EECCCCCCCCCCCCH	30.61	25521595
2030	Phosphorylation	TSTKTTRSPDTSAYC CCCCCCCCCCCCHHH	25.65	25521595
2033	Phosphorylation	KTTRSPDTSAYCYET CCCCCCCCCHHHHHH	20.74	25521595
2034	Phosphorylation	TTRSPDTSAYCYETM CCCCCCCCHHHHHHH	25.31	25521595
2036	Phosphorylation	RSPDTSAYCYETMEK CCCCCCHHHHHHHHH	8.71	25619855
2038	Phosphorylation	PDTSAYCYETMEKIT CCCCHHHHHHHHHHC	11.19	25619855
2040	Phosphorylation	TSAYCYETMEKITKT CCHHHHHHHHHHCCC	12.26	25619855
2045	Phosphorylation	YETMEKITKTPQAST HHHHHHHCCCCCCCC	39.68	25619855
2047	Phosphorylation	TMEKITKTPQASTYS HHHHHCCCCCCCCCE	16.39	25619855
2051	Phosphorylation	ITKTPQASTYSYETS HCCCCCCCCCEEECC	23.72	25619855
2052	Phosphorylation	TKTPQASTYSYETSD CCCCCCCCCEEECCC	21.36	25619855
2053	Phosphorylation	KTPQASTYSYETSDR CCCCCCCCEEECCCC	13.53	22817900
2054	Phosphorylation	TPQASTYSYETSDRC CCCCCCCEEECCCCC	19.31	30372032
2055	Phosphorylation	PQASTYSYETSDRCY CCCCCCEEECCCCCE	16.89	22817900
2058	Phosphorylation	STYSYETSDRCYTTE CCCEEECCCCCEECC	15.89	30372032
2060	Methylation	YSYETSDRCYTTEKK CEEECCCCCEECCCC	18.34	24129315
2062	Phosphorylation	YETSDRCYTTEKKSP EECCCCCEECCCCCH	20.00	23335269
2063	Phosphorylation	ETSDRCYTTEKKSPS ECCCCCEECCCCCHH	31.91	23335269
2064	Phosphorylation	TSDRCYTTEKKSPSE CCCCCEECCCCCHHH	21.23	30372032
2068	Phosphorylation	CYTTEKKSPSEARQD CEECCCCCHHHHHHC	44.73	25521595
2070	Phosphorylation	TTEKKSPSEARQDVD ECCCCCHHHHHHCCC	51.48	25521595
2082	Phosphorylation	DVDLCLVSSCEFKHP CCCEEEEECCCCCCC	19.14	-
2083	Phosphorylation	VDLCLVSSCEFKHPK CCEEEEECCCCCCCC	15.36	21659604
2091	Phosphorylation	CEFKHPKTELSPSFI CCCCCCCCCCCHHHC	46.76	25177544
2094	Phosphorylation	KHPKTELSPSFINPN CCCCCCCCHHHCCCC	16.56	26824392
2096	Phosphorylation	PKTELSPSFINPNPL CCCCCCHHHCCCCCC	35.07	24453211
2112	Phosphorylation	WFAGEEPTEESEKPL HHCCCCCCCCCCCCC	56.52	25777480
2115	Phosphorylation	GEEPTEESEKPLTQS CCCCCCCCCCCCCCC	44.69	25777480
2117	Acetylation	EPTEESEKPLTQSGG CCCCCCCCCCCCCCC	55.39	155677
2120	Phosphorylation	EESEKPLTQSGGAPP CCCCCCCCCCCCCCC	29.26	25777480
2122	Phosphorylation	SEKPLTQSGGAPPPS CCCCCCCCCCCCCCC	33.68	21183079
2129	Phosphorylation	SGGAPPPSGGKQQGR CCCCCCCCCCCCCCC	66.99	25777480
2152	Phosphorylation	SVSESAPSQTDSDVP CCCCCCCCCCCCCCC	45.49	25338131
2162	Phosphorylation	DSDVPPETEECPSIT CCCCCCCCCCCCCCC	42.74	25338131
2176	Phosphorylation	TADANIDSEDESETI CCCCCCCCCCCCCCC	43.05	25338131
2205	Phosphorylation	PAPMQDRSPSPRHPD CCCCCCCCCCCCCCC	37.71	25521595
2207	Phosphorylation	PMQDRSPSPRHPDVS CCCCCCCCCCCCCCC	35.49	25521595
2232	Ubiquitination	QNLGKALKKDLKEKT HHHHHHHHHHHHHHH	49.45	-
2246	Phosphorylation	TKTKKPGTKTKSSSP HCCCCCCCCCCCCCC	44.03	20139300
2250	Phosphorylation	KPGTKTKSSSPVKKG CCCCCCCCCCCCCCC	41.08	23335269
2251	Phosphorylation	PGTKTKSSSPVKKGD CCCCCCCCCCCCCCC	39.97	23335269
2252	Phosphorylation	GTKTKSSSPVKKGDG CCCCCCCCCCCCCCC	40.58	21454597
2267	Phosphorylation	KSKPLAASPKPGALK CCCCCCCCCCCCCCC	28.05	26824392
2276	Phosphorylation	KPGALKESSDKVSRV CCCCCCCCCCHHHHC	42.10	28066266
2277	Phosphorylation	PGALKESSDKVSRVA CCCCCCCCCHHHHCC	42.41	28066266
2285	Phosphorylation	DKVSRVASPKKKESV CHHHHCCCCCHHHHH	34.10	22817900
2298	Phosphorylation	SVEKATKTTTTPEVK HHHHHCCCCCCHHHH	25.64	25521595
2300	Phosphorylation	EKATKTTTTPEVKAT HHHCCCCCCHHHHCC	45.65	29899451
2301	Phosphorylation	KATKTTTTPEVKATR HHCCCCCCHHHHCCC	18.50	25521595
2325	Phosphorylation	NAANASASKSAKTAT HHHHHHHCCCCCCCC	25.34	18779572
2357	S-nitrosocysteine	LPVYLDLCYIPNHSN CCEEEEEEECCCCCC	2.63	-
2357	S-nitrosylation	LPVYLDLCYIPNHSN CCEEEEEEECCCCCC	2.63	22178444
2380	Phosphorylation	FKRVRSSYYVVSGND HHHHHCCEEEEECCC	11.09	21183079
2394	Phosphorylation	DPAAEEPSRAVLDAL CCCCCCCCHHHHHHH	35.83	22817900
2410	Phosphorylation	EGKAQWGSNMQVTLI HCCCCCCCCCEEEEE	26.60	22817900
2460	S-nitrosocysteine	QDESFPACKIEL--- CCCCCCCCEECC---	4.67	-
2460	S-nitrosylation	QDESFPACKIEL--- CCCCCCCCEECC---	4.67	17704770

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1247	S	Phosphorylation	Kinase	MTOR	Q9JLN9	PSP
1260	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
1260	S	Phosphorylation	Kinase	GSK3B ISO2	P49841-2	PSP
1260	S	Phosphorylation	Kinase	GSK3B	Q9WV60	PSP
1260	S	Phosphorylation	Kinase	GSK3B	P18266	PSP
1260	S	Phosphorylation	Kinase	MTOR	Q9JLN9	PSP
1265	T	Phosphorylation	Kinase	GSK3B	Q9WV60	PSP
1265	T	Phosphorylation	Kinase	GSK3B	P18266	PSP
1784	T	Phosphorylation	Kinase	MAPK1	P63085	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	Gan	Q8CA72	PMID:22199232

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
2460	C	S-nitrosylation		17704770
S-nitrosylation at Cys-2460 enhances interaction with microtubules, and may act as an effector modification for neuronal nitric oxide synthase control of growth-cone size, growth-cone collapse and axon retraction.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MAP1B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NBR1_MOUSE	Nbr1	physical	22654911
LIS1_MOUSE	Pafah1b1	physical	15762842
NXF1_MOUSE	Nxf1	physical	16014633
STRAP_MOUSE	Strap	physical	16014633
STAU1_MOUSE	Stau1	physical	16014633
U2AF1_MOUSE	U2af1	physical	16014633

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MAP1B_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-614; SER-1438; SER-1497AND SER-1775, AND MASS SPECTROMETRY.	19131326 [Abstract]
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-825; SER-828; SER-829;SER-989; SER-992; SER-1247; SER-1251; SER-1260; SER-1422 AND SER-1438,AND MASS SPECTROMETRY.	19367708 [Abstract]
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations."; Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.; Mol. Cell. Proteomics 6:283-293(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-527; SER-829; SER-1151;SER-1204; SER-1260; SER-1307; SER-1317; SER-1334; SER-1384; SER-1391;SER-1395; SER-1497; SER-1775; SER-1781; SER-1789; TYR-1792; SER-1813;SER-1815; SER-1877; SER-1911; THR-1945 AND SER-2030, AND MASSSPECTROMETRY.	17114649 [Abstract]
"A differential phosphoproteomic analysis of retinoic acid-treated P19cells."; Smith J.C., Duchesne M.A., Tozzi P., Ethier M., Figeys D.; J. Proteome Res. 6:3174-3186(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-828 AND SER-829, ANDMASS SPECTROMETRY.	17622165 [Abstract]
"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations."; Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.; Mol. Cell. Proteomics 5:914-922(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-541; SER-544; SER-561;SER-614; SER-989; SER-1013; SER-1307; SER-1391; SER-1438; SER-1497;SER-1775; SER-1911; THR-1928 AND SER-2068, AND MASS SPECTROMETRY.	16452087 [Abstract]
"Proteomic analysis of in vivo phosphorylated synaptic proteins."; Collins M.O., Yu L., Coba M.P., Husi H., Campuzano I.,Blackstock W.P., Choudhary J.S., Grant S.G.; J. Biol. Chem. 280:5972-5982(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-828; SER-829; SER-1247;SER-1255; SER-1260; SER-1307; SER-1317; TYR-1331; SER-1334; SER-1371;SER-1373; SER-1382; SER-1384; SER-1391; SER-1395; SER-1616; SER-1621;SER-1768; SER-1775; SER-1778; SER-1781; THR-1784; SER-1793; THR-1806;SER-1877; SER-1911; SER-2030 AND SER-2094, AND MASS SPECTROMETRY.	15572359 [Abstract]
"Phosphoproteomic analysis of the developing mouse brain."; Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.; Mol. Cell. Proteomics 3:1093-1101(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-934; SER-1151; THR-1277;SER-1255; SER-1260; SER-1319; TYR-1332; SER-1334; SER-1373; SER-1384;SER-1391; SER-1395; SER-1403; SER-1497; SER-1789 AND SER-1793, ANDMASS SPECTROMETRY.	15345747 [Abstract]
S-nitrosylation
Reference	PubMed
"S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction."; Stroissnigg H., Trancikova A., Descovich L., Fuhrmann J.,Kutschera W., Kostan J., Meixner A., Nothias F., Propst F.; Nat. Cell Biol. 9:1035-1045(2007). Cited for: S-NITROSYLATION AT CYS-2460.	17704770 [Abstract]

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