LRK42_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRK42_ARATH
• UniProt AC: Q9M345
• Protein Name: L-type lectin-domain containing receptor kinase IV.2 {ECO:0000303|PubMed:19773388}
• Gene Name: LECRK42 {ECO:0000303|PubMed:19773388}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 677
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Required during pollen development.; Involved in resistance response to the pathogenic bacteria Pseudomonas syringae..
• Protein Sequence: MFVKLKLIFFFFLLCQIMISSSQNLNFTYNGFHPPLTDISLQGLATVTPNGLLKLTNTSVQKTGHAFCTERIRFKDSQNGNVSSFSTTFVFAIHSQIPTLSGHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRLNGEAPMLSLSKLPKLPRFEPRRISEFYKIGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWETEFGKNRFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPELTPLDLSAGSVMNLGGRDGFSGIAMTDFSTVFKGFTGGSSIADSLLSGGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	N-linked_Glycosylation	ISSSQNLNFTYNGFH HHCCCCCCCEECCCC	34.46	-
57	N-linked_Glycosylation	NGLLKLTNTSVQKTG CCEEEEECCCCHHCC	40.57	-
81	N-linked_Glycosylation	FKDSQNGNVSSFSTT EECCCCCCCCEEEEE	37.74	-
128	N-linked_Glycosylation	SQYIGLFNISNNGND CCEEEEEEEECCCCC	41.65	-
134	N-linked_Glycosylation	FNISNNGNDTNHIFA EEEECCCCCCCEEEE	55.87	-
171	N-linked_Glycosylation	LNGLRSANYSTAGYR CCCCCCCCCCCCCCC	32.31	-
186	N-linked_Glycosylation	DDHDKFQNLSLISRK CCCHHHHCHHHEECC	34.43	-
188	Phosphorylation	HDKFQNLSLISRKRI CHHHHCHHHEECCEE	31.07	24243849
203	N-linked_Glycosylation	QVWIDYDNRSHRIDV EEEEECCCCCCEEEE	40.92	-
501	Phosphorylation	ARLYDHGSDPQTTHV EEECCCCCCCCCEEE	42.57	23111157
505	Phosphorylation	DHGSDPQTTHVVGTL CCCCCCCCEEEEEEC	25.02	23111157
506	Phosphorylation	HGSDPQTTHVVGTLG CCCCCCCEEEEEECC	13.87	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRK42_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRK42_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRK42_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
WAK3_ARATH	WAK3	physical	24833385
VAP21_ARATH	AT5G47180	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.