| UniProt ID | INTU_DROME | |
|---|---|---|
| UniProt AC | Q9VPH0 | |
| Protein Name | Protein inturned | |
| Gene Name | in | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 869 | |
| Subcellular Localization | Cytoplasm . Cell membrane . Localizes in the vicinity of plasma membrane and the cortical actin cytoskeleton of wing disk and pupal wing cells (PubMed:10570461). Localizes to the proximal side of wing cells, fuz and frtz are required for its localiza | |
| Protein Description | Plays a role in the definition of cell polarity via the planar cell polarity (PCP) cascade. Acts downstream of fuz and accumulates asymmetrically in wing cells to regulate planar polarity in the wing. Probably acts by regulating ciliogenesis.. | |
| Protein Sequence | MRKSPASLPSEAFSSSNSSLSNSYSDGSDLANWEEYVSTDGSLFYMEYVRCEKTGVSAERRVEFMRRSLRLGKKSSRRQPHSNNQNQSQNQNQSHGPSRLDSQTEPQEFRFSQFKTAAPDPKKLDLVITAADRFRFGRRSTAVESILGFRVLPFPDQPECLMVDGFVHDVSALQHGIKRGDWFRSLNGIEVYASNVDELLKQFVEPTQVCLGFQSCGAASAVSPTDPGYNRNVREEQVCKVENFPMFTEKFEQMLITEGNFGIPGSSVDIRMPFAMLLLPPECYQHEQQQDSLYYFPEIPDNFLFKARGSFLTLHAVLSELHTQPLSSRLLVDQVQYHVNYRQLNGFLVLFAYAGGLCCAAECSLRSDELIGYIRFSLPGLVLESFNQEREPGNSSRLKLFLRHFCEIQRTRLVARCHGHIRFEELLGQSRSLPLPKEAQLRIFDALSEMEAMDYRNWNDEPLTTHREFFIYGSALYYDGFLVASLLPPEVRVSVEGFLRCRGIFELLGAAPGIKVREMYVWEEIVLPSATGRYFLTICTKNHLSLAVILKIFDAPDMAPDAVVGPSLFYIEEIQETLDHLVQCGIESLAMFWSVSNKRPEVLDATASESRDQEKEPNNRLESFLKQKLTVLSPSVEEEAQLCSSLGGSSIHSLTPSEDESCRRRLTPIHGTAEDSDSGSDWENFAVQHPLHYGLNLGAESHSQSQMTESMWKEINNVVPVKISAGWKNSVLHYVYIDIANGSLFAPFTDSSENSNYLSEIRQACHIIHAVLQKSKHYRRHLSESSRAQTNSNGHSSHTVSLVKEHGMILEVSTQPKSDGQSQSSTSSRFVVVGRLFQSPAKEVYVCHRSDVPQNIVEMAFRLSFFSMG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of INTU_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of INTU_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of INTU_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of INTU_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DSH_DROME | dsh | genetic | 11973308 | |
| FRITZ_DROME | frtz | genetic | 15654087 | |
| FRITZ_DROME | frtz | genetic | 25072625 | |
| FUZZY_DROME | fy | genetic | 25072625 | |
| STAN_DROME | stan | genetic | 11973308 | |
| FRIZ_DROME | fz | genetic | 11973308 | |
| PRIC1_DROME | pk | genetic | 11973308 | |
| FRITZ_DROME | frtz | physical | 25072625 | |
| FUZZY_DROME | fy | physical | 25072625 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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