dbPTM

FUZZY_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FUZZY_DROME
UniProt AC	O16868
Protein Name	Protein fuzzy
Gene Name	fuz
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	416
Subcellular Localization	Cytoplasm . Cytoplasm, cytoskeleton .
Protein Description	Plays a role in the organization of cell polarity via a planar cell polarity (PCP) cascade. Involved in the development of the hairs on the wings. Specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cells. Controls wing cell hair number by maintaining the integrity of the cytoskeletal components that direct hair development..
Protein Sequence	MSIYLLCLTTNGGLPVFTRKKGECENLPFSTVASLNGFHMFFKSLGIQLEATTTSKQQPIQNQAPADAEEWTYIWRDRESITLIVCGCGVGSEQLLQTLADLVFGAIGMFITRAAEMAHATLLDRLKKDAKKYVPIVDAILEAACAGTQLLGYTDCLLAAENAQLLQCLNEFSGHCGSLFCCLVVGHRIAVATEGWWDLDTRDRELLLFLLNSSSTMQHDVPVYLPVKSPHIAYRFVSIPVASNSALCVLCGAENASFRELHAHAMSAYRNEGNLLAAAERCVPRSLPEHLEIDGNVLAIILINRHTRKSLFTRNLNQSASVKRIIVGDLQRLDILKKFFDQTMDAVHQFETQSSSNKTTLVDQYSCSDYHKCYAHMDELGNVIFLLFVAAVPSHAMRFLAQRIHANILQEKSVCW

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of FUZZY_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FUZZY_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FUZZY_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FUZZY_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FRITZ_DROME	frtz	genetic	15654087
STAN_DROME	stan	genetic	11973308
FRIZ_DROME	fz	genetic	11973308
FRITZ_DROME	frtz	physical	25072625
INTU_DROME	in	physical	25072625

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FUZZY_DROME

Related Literatures of Post-Translational Modification