dbPTM

FRITZ_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FRITZ_DROME
UniProt AC	Q9VQ36
Protein Name	WD repeat-containing and planar cell polarity effector protein fritz
Gene Name	frtz
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	951
Subcellular Localization	Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme.
Protein Description	Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Functions cell autonomously to regulate wing cell hair polarity and number..
Protein Sequence	MLLSETHFWTTLREDVVRIKSQDLGAFRYLRQRDKEQEQQDLACLAKRDYTERRNGLAVLKNSGRKSTGRLKDNLKKLEDLLRQHRIIHSEWQDAAQVLLLFSHGLIAHICVDIYTGDILRMVFEKYLVGKLASEVITDAFFTRSHIVLAYNTNQLTVVHLQRPNARSQGPEKIANMDPRIFHVIIPGATERKLSRHLTVNASFDLFVVWTQSSQNEVYPWRPTIRDQDRANIHVFKIKGLQLESIAYCWSENDPLCVDFLRSSESQIITLEQKVSRKGDISAEICSYELAAGKMQRTAITSIPMGAQICSFAFSPDQEKLFLGSVDRNICLHDLVQQSTKYANQIEIVPNQCAWHCDSAMLCVANERSVLQCFDLALATIGHQLVSENVTPSSLLDLSHYFVAQPTLLSVAFSRKPDLSTFKHTYAQTDCLLLLVYEQGPLACMRIFGGTGMRGDIHNSGLTADVIADKYLRLQQPDRAVNVLAALNWETYGAMCLITLHKIANYVFFGGDQRRPRIELMARALKTFAHTLSEETKDEFSDQVYDLKRRFCFYLLRKNLFAEAFEIAQDVADYDIFMDLYNLTKCISSLSEFAQVAFSQAAAIIHEEDRANGNLSLTCDLRSESACSLSTCSDMLRGQGAGTAPETGLGASQPQSQQVLKNYVPPLPSFKSKVFNAEMIKINIPKPELRPPLPKVSIAPPTSSLASLTLKSNSSLQQAPAKSLHPNGNLWSQDVPDQTVGLPMASSPLPRLPPSNIPDQSAQLGQFSTMPASPPPTGSYQPKFYQHPLVSGNIPAMLPSLTSEDYQKRLLQKKPTASILSNPANPAPTNGEAPATPAKSQTAEKNKVKFSDTIQVAVVPEIPRKEKPMPPKRNGYSRPAARHLTNPKKELADSLPLCHPNDEYLKDFNPITTNVTKPPIRRREEEPKSSSKGGNSSSSSSSIKVVHFGVV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of FRITZ_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FRITZ_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FRITZ_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FRITZ_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FUZZY_DROME	fy	genetic	15654087
INTU_DROME	in	genetic	15654087
INTU_DROME	in	physical	25072625

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FRITZ_DROME

Related Literatures of Post-Translational Modification