dbPTM

IF4A3_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IF4A3_DROME
UniProt AC	Q9VHS8
Protein Name	Eukaryotic initiation factor 4A-III {ECO:0000303\|PubMed:22961380}
Gene Name	CG7483 {ECO:0000312\|FlyBase:FBgn0037573}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	399
Subcellular Localization	Nucleus .
Protein Description	ATP-dependent RNA helicase. [PubMed: 22961380 Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs]
Protein Sequence	MARKNAQAEDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDIRKLDYGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADLI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of IF4A3_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of IF4A3_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of IF4A3_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IF4A3_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NOL9_DROME	CG8414	physical	14605208
CWC22_DROME	ncm	physical	22961380
SAP18_DROME	Bin1	physical	22961380
RBM8A_DROME	tsu	physical	22961380
DX39B_DROME	Hel25E	physical	22961380
RBM8A_DROME	tsu	physical	14973490
RBM8A_DROME	tsu	physical	24967911
MGN_DROME	mago	physical	14973490
MGN_DROME	mago	physical	24967911

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IF4A3_DROME

Related Literatures of Post-Translational Modification