IDLC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IDLC_HUMAN
• UniProt AC: O14645
• Protein Name: Axonemal dynein light intermediate polypeptide 1
• Gene Name: DNALI1
• Organism: Homo sapiens (Human).
• Sequence Length: 258
• Subcellular Localization: Cell projection, cilium .
• Protein Description: May play a dynamic role in flagellar motility..
• Protein Sequence: MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MIPPADSLLKYDTP -CCCCHHHHCCCCCC	37.39	24719451
34	Phosphorylation	KARLLKVSPQQPGPS CCEEEECCCCCCCCC	18.53	27966365
54	Phosphorylation	PPKTKLPSTPCVPDP CCCCCCCCCCCCCCC	56.25	28857561
55	Phosphorylation	PKTKLPSTPCVPDPT CCCCCCCCCCCCCCC	20.83	28857561
171	Phosphorylation	YQTLYESSVAFGMRK HHHHHHHHHHHHHHH	12.91	-
198	Phosphorylation	RKIAELETEKRDLER HHHHHHHHHHHHHHH	60.47	28102081
222	Phosphorylation	EATEKRESERRQVEE HHHHHHHHHHHHHHH	40.20	17081983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IDLC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IDLC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IDLC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IDLC_HUMAN	DNALI1	physical	21900206
A4_HUMAN	APP	physical	21832049
ANM6_HUMAN	PRMT6	physical	23455924
GELS_HUMAN	GSN	physical	27173435
PROF2_HUMAN	PFN2	physical	27173435
EIF3K_HUMAN	EIF3K	physical	27173435
SESD1_HUMAN	SESTD1	physical	27173435
ARPC4_HUMAN	ARPC4	physical	27173435
BL1S3_HUMAN	BLOC1S3	physical	27173435
FBX30_HUMAN	FBXO30	physical	27173435
DYN2_HUMAN	DNM2	physical	27173435
ARP3_HUMAN	ACTR3	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.