HXD10_MOUSE - dbPTM
HXD10_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HXD10_MOUSE
UniProt AC P28359
Protein Name Homeobox protein Hox-D10
Gene Name Hoxd10
Organism Mus musculus (Mouse).
Sequence Length 340
Subcellular Localization Nucleus.
Protein Description Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis..
Protein Sequence MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTANIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNESASGQEPTKVSQVESPEAKGGLPEDRSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
125PhosphorylationDKRNKLISAEVPSYQ
CCCCEEEEEECCCHH
28.9021189417
130PhosphorylationLISAEVPSYQRLVPE
EEEEECCCHHHCCCC
38.7921189417
191PhosphorylationGAAKPQLSAAQLQME
CCCCCCCCHHHHHHH
19.1321454597
206PhosphorylationKKMNESASGQEPTKV
HHHCCCCCCCCCCCE
50.7321659604
211PhosphorylationSASGQEPTKVSQVES
CCCCCCCCCEECCCC
43.2421659604
218PhosphorylationTKVSQVESPEAKGGL
CCEECCCCCCCCCCC
29.2325195567
236PhosphorylationRSCLAEVSVSSPEVQ
CCCEEEEECCCHHHH
14.0526239621
238PhosphorylationCLAEVSVSSPEVQEK
CEEEEECCCHHHHHH
32.4426239621
239PhosphorylationLAEVSVSSPEVQEKE
EEEEECCCHHHHHHH
23.9526239621
257PhosphorylationEIKSDTPTSNWLTAK
HHHCCCCCCCCEECC
36.4622871156
262PhosphorylationTPTSNWLTAKSGRKK
CCCCCCEECCCCCCC
24.5322871156
302PhosphorylationRRLEISKSVNLTDRQ
HHHEECCCCCCCHHH
14.9428059163
306PhosphorylationISKSVNLTDRQVKIW
ECCCCCCCHHHHHHH
24.7528059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HXD10_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HXD10_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HXD10_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PBX1_MOUSEPbx1physical
20211142
PBX2_MOUSEPbx2physical
20211142
PBX3_MOUSEPbx3physical
20211142
ZN292_MOUSEZfp292physical
20211142

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HXD10_MOUSE

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Related Literatures of Post-Translational Modification

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