ZN292_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN292_MOUSE
• UniProt AC: Q9Z2U2
• Protein Name: Zinc finger protein 292 {ECO:0000312|EMBL:CAM27828.1, ECO:0000312|MGI:MGI:1353423}
• Gene Name: Zfp292 {ECO:0000312|EMBL:AAH08537.1, ECO:0000312|MGI:MGI:1353423}
• Organism: Mus musculus (Mouse).
• Sequence Length: 2698
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MADDEAEQERLSGGGCAAELRRLGERLQELERRLCESREPAVEAAAAYCRQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECESVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHETLMESGSCELQFLATLAQETGVWKNAVLSTILSQEPLDKEKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPSEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSVQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPEDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVDYQGERGDTSVNGLSAAGLGTDSGLLMDTGDEKQKKKEIKELKDRGFISARFRNWQAYMQYCLLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKDSFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATHENQKTNINTVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDSEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLAHRKEHQVFRAKCLFPKCGRIFSQAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSEMEKHQDGHSHPETGLPPEDQLQPSGNDVNPDSGATAAGGRSENSIDKNLGSNRSADWEKNRAEPAVTKHGQISAAELRQANIPLSNGLETRDNTTVLRTNEVAVSIKVSVNHGVEGDFGKQENLTMEGTGEPLITDVHKPGIGAGVQLCHPGFQEKKGHECLNEAQNSLSNSESLKMDDLNPQSLERQVNTLMTFSVQNEAGLEDNSQICKFECGGDVKTSSSLYDLPLKTLESITFVQSQPDLSSPLGSPSVPPKAPGQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKLQRKTKKGQKSNNLNTPNHGKCVYFLPSQVSSSNHAFFTPQTKANGNPACSAQVQHVSPSIFPAHLASVSAPLLPSVESVLSPNIPSQDKHGQDGILCSQMENLSNAPLPAQMEDLTKTVLPLNIDSGSDPFLPLPTENSSLFSSPADSENNSVFSQLENSTNHYPSQTDGNINSSFLKGGSSENGVFPSQVSSADDFSSTSAQPSTPKKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQTNRQPSLLASMILSTSAVNMQQPQQSNFNPETCFKDPSFLQLLNVENRPTFLPSTFPRCDVSNFNASVSQEGSEIIKQALETAGIPSTFESAEMLSQVVPIGSVSDAAQVSAAGMPGPPVTPLLQTVCHPNTSPSNQNQTPNSKTLKECNSLPLFTTNDLLLKTIENGLCSNSFSSSTEPPQNFTNNSAHVSVISGPQNTRSSHLNKKGNSASKKRKKVAPAVSVSNTSQNVLPTDLPVGLPAKNLPVPDTNTRSDMTPDCEPRALVENLTQKLNNIDNHLFITDVKENCKASLEPHTMLTPLTLKTENGDSRMMPLSSCTPVNSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGTGETTQNAQINYSMQLPSVNSIPDNKLPDASQCSSFLTVMPTKSEALHKEDQIQDILEGLQNLKLENDTSAPASQSMLMNKSVALSPTPTKSTPNIVVQPVPEVIHVQLNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPSCTKTFTRNSNLRAHCQLVHHFTIEEMVKLKIKRPYGRKSQSENLSSPQNNQVKKQPSMAEETKTESQPAFKVPAATGDAALANATVIPEKQLAEKKSPEKPESSSQPVTSSAEQYNANLANLKTKGRKNKRHRKEKEEKREKNPVSQAFELPTKYSSYRPYCCVHQGCFAAFTIQQNLILHYQAVHKSNLPTFSAEVEEESEAVKESEETEPKQSMKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTAAVDVGKFPCDQLECKLSFTTYLSYVVHLEVDHGIGTRTSKAEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRKLTGQENISSKANQEKSKSKHRTTKPNRSGKDGMKMPKTKRKKKSNLENKSAKVVQIEENKPYSLKRGKHVYSIKARNDALAECTSKFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSRAFTSQHRNILIVFKRYGNPQGKEISEQEDEKNDKKDPDSSVLEKNDNSEPAAAPQEEGRKGEKDEMDELTELFITKLINEDSTNAENQGNTTLKGNNEFQEHDSCTSERQKPGNLKRVYKEKNTVQSKKRKIDKTEPEVSLVVNNTRKEEEPAVAVQTTEEHPASFDWSSFKPMGFEASFLKFLEESAVKQKKNSDRDHSNSGSKRGSHSSSRRHVDKAAVAGSSHVCSCKDSEIFVQFANPSKLQCSENVKIVLDKTLKDRSELVLKQLQEMKPTVSLKKLEVLSNNPDRTVLKEISIGKATGRGQY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
509	Phosphorylation	DSGLLMDTGDEKQKK CCCCCCCCCCHHHHH	32.35	-
614	Phosphorylation	LGRPPKITATHENQK CCCCCCCCCCCCCCC	31.46	25159016
616	Phosphorylation	RPPKITATHENQKTN CCCCCCCCCCCCCCC	22.52	25159016
654	Phosphorylation	VFNDNDGSDDENDDK EEECCCCCCCCCCCC	44.76	21149613
804	Phosphorylation	YDHEAQHYNTYTCKF HCCCCCCCCEEEEEE	9.34	-
997	Phosphorylation	NSLSNSESLKMDDLN HHCCCCCCCCHHCCC	32.86	23140645
1043	Phosphorylation	ECGGDVKTSSSLYDL EECCCCCCCCCCCCC	33.42	-
1104	Acetylation	NSSQSIGKHMKTAHP CCCCCHHHHHCCCCH	38.56	23806337
1114	Phosphorylation	KTAHPDQYAAFKLQR CCCCHHHHHHHHHHH	13.79	-
1146	Phosphorylation	KCVYFLPSQVSSSNH CEEEECCCCCCCCCC	45.41	-
1317	Phosphorylation	VSSADDFSSTSAQPS CCCCCCCCCCCCCCC	39.44	25619855
1324	Phosphorylation	SSTSAQPSTPKKVKK CCCCCCCCCCCCCCC	45.31	25619855
1325	Phosphorylation	STSAQPSTPKKVKKD CCCCCCCCCCCCCCC	45.90	25619855
1701	Phosphorylation	LEPHTMLTPLTLKTE CCCCCEEECEEEECC	12.87	22006019
1793	Phosphorylation	DNKLPDASQCSSFLT CCCCCCHHHCCHHEE	38.82	25338131
1800	Phosphorylation	SQCSSFLTVMPTKSE HHCCHHEEECCCHHH	16.85	25338131
1804	Phosphorylation	SFLTVMPTKSEALHK HHEEECCCHHHHHCC	29.16	25338131
1844	Phosphorylation	QSMLMNKSVALSPTP HHHHCCCCEEECCCC	13.97	28833060
1848	Phosphorylation	MNKSVALSPTPTKST CCCCEEECCCCCCCC	19.59	26824392
1850	Phosphorylation	KSVALSPTPTKSTPN CCEEECCCCCCCCCC	39.97	26824392
1852	Phosphorylation	VALSPTPTKSTPNIV EEECCCCCCCCCCEE	39.85	28833060
1976	Phosphorylation	SQSENLSSPQNNQVK CCCCCCCCCCCCCCC	33.40	27841257
1996	Phosphorylation	AEETKTESQPAFKVP HHCCCCCCCCCCCCC	46.85	28576409
2020	Acetylation	NATVIPEKQLAEKKS CCEECCHHHHHCCCC	45.30	23806337
2027	Phosphorylation	KQLAEKKSPEKPESS HHHHCCCCCCCCCCC	49.73	25619855
2033	Phosphorylation	KSPEKPESSSQPVTS CCCCCCCCCCCCCCC	43.76	25619855
2034	Phosphorylation	SPEKPESSSQPVTSS CCCCCCCCCCCCCCC	31.19	25619855
2035	Phosphorylation	PEKPESSSQPVTSSA CCCCCCCCCCCCCCH	48.02	25619855
2039	Phosphorylation	ESSSQPVTSSAEQYN CCCCCCCCCCHHHHH	24.52	20139300
2040	Phosphorylation	SSSQPVTSSAEQYNA CCCCCCCCCHHHHHH	27.99	20139300
2041	Phosphorylation	SSQPVTSSAEQYNAN CCCCCCCCHHHHHHH	26.85	20139300
2472	Phosphorylation	TKLINEDSTNAENQG HHHHCCCCCCCCCCC	19.86	28066266
2473	Phosphorylation	KLINEDSTNAENQGN HHHCCCCCCCCCCCC	51.25	28066266
2481	Phosphorylation	NAENQGNTTLKGNNE CCCCCCCCCCCCCCC	40.09	30635358
2482	Phosphorylation	AENQGNTTLKGNNEF CCCCCCCCCCCCCCC	30.39	30635358
2577	Phosphorylation	FLKFLEESAVKQKKN HHHHHHHHHHHHHCC	29.05	28066266
2666	Phosphorylation	QLQEMKPTVSLKKLE HHHHHCCCEEEEEEH	19.74	29895711

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN292_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN292_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN292_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
OLIG1_MOUSE	Olig1	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.