ERL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERL1_ARATH
• UniProt AC: C0LGW6
• Protein Name: LRR receptor-like serine/threonine-protein kinase ERL1 {ECO:0000303|PubMed:14985254}
• Gene Name: ERL1 {ECO:0000303|PubMed:14985254}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 966
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ER and ERL2. Redundantly involved with ER in procambial development regulation. Forms a functional ligand-receptor pair with EPF1 (AC Q8S8I4). [PubMed: 22241782 Forms a constitutive complex with TMM involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN]
• Protein Sequence: MKEKMQRMVLSLAMVGFMVFGVASAMNNEGKALMAIKGSFSNLVNMLLDWDDVHNSDLCSWRGVFCDNVSYSVVSLNLSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITGEIPYNIGFLQVATLSLQGNRLTGRIPEVIGLMQALAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIPSELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQFNVHGNLLSGSIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFSGSIPLTLGDLEHLLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFNLLSGVIPTELGQLQNLNSLILNNNKLHGKIPDQLTNCFTLVNLNVSFNNLSGIVPPMKNFSRFAPASFVGNPYLCGNWVGSICGPLPKSRVFSRGALICIVLGVITLLCMIFLAVYKSMQQKKILQGSSKQAEGLTKLVILHMDMAIHTFDDIMRVTENLNEKFIIGYGASSTVYKCALKSSRPIAIKRLYNQYPHNLREFETELETIGSIRHRNIVSLHGYALSPTGNLLFYDYMENGSLWDLLHGSLKKVKLDWETRLKIAVGAAQGLAYLHHDCTPRIIHRDIKSSNILLDENFEAHLSDFGIAKSIPASKTHASTYVLGTIGYIDPEYARTSRINEKSDIYSFGIVLLELLTGKKAVDNEANLHQLILSKADDNTVMEAVDPEVTVTCMDLGHIRKTFQLALLCTKRNPLERPTMLEVSRVLLSLVPSLQVAKKLPSLDHSTKKLQQENEVRNPDAEASQWFVQFREVISKSSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	N-linked_Glycosylation	WRGVFCDNVSYSVVS EECEECCCCCEEEEE	26.30	-
77	N-linked_Glycosylation	SYSVVSLNLSSLNLG CEEEEEEECHHCCCC	30.30	-
226	N-linked_Glycosylation	YFDVRGNNLTGTIPE EEEECCCCCEECCCC	41.63	-
237	N-linked_Glycosylation	TIPESIGNCTSFQIL CCCCCCCCCCEEEEE	24.99	-
308	N-linked_Glycosylation	PIPPILGNLSFTGKL CCCCCCCCCEECCEE	29.12	-
332	N-linked_Glycosylation	PIPSELGNMSRLSYL CCCHHHCCCCCEEEE	37.57	-
377	N-linked_Glycosylation	LVGPIPSNISSCAAL CCCCCCCCHHHHHHH	32.57	-
412	N-linked_Glycosylation	LGSLTYLNLSSNNFK CCCCEEEECCCCCCC	27.71	-
441	N-linked_Glycosylation	KLDLSGNNFSGSIPL CCCCCCCCCCCCCCE	35.67	-
460	N-linked_Glycosylation	LEHLLILNLSRNHLS HHHHHHHCCCCCCCC	29.04	-
532	N-linked_Glycosylation	CFTLVNLNVSFNNLS CEEEEEEEEECCCCC	23.37	-
537	N-linked_Glycosylation	NLNVSFNNLSGIVPP EEEEECCCCCCCCCC	33.31	-
539	Phosphorylation	NVSFNNLSGIVPPMK EEECCCCCCCCCCCC	28.70	28011693
547	N-linked_Glycosylation	GIVPPMKNFSRFAPA CCCCCCCCCCCCCCH	33.60	-
637	Phosphorylation	HMDMAIHTFDDIMRV HHHHHHHCHHHHHHH	23.73	-
645	Phosphorylation	FDDIMRVTENLNEKF HHHHHHHHHCCCCCE	14.59	-
721	Phosphorylation	PTGNLLFYDYMENGS CCCCEEEEEECCCCC	13.21	-
760	Phosphorylation	GAAQGLAYLHHDCTP HHHHHHHHHCCCCCC	16.18	-
815	Phosphorylation	YVLGTIGYIDPEYAR EEEEECCCCCHHHHC	9.78	-
823	Phosphorylation	IDPEYARTSRINEKS CCHHHHCCCCCCCCC	17.74	-
920	Phosphorylation	VLLSLVPSLQVAKKL HHHHHHCHHHHHHHC	24.77	28011693
933	Phosphorylation	KLPSLDHSTKKLQQE HCCCCCHHHHHHHHH	41.40	19880383
934	Phosphorylation	LPSLDHSTKKLQQEN CCCCCHHHHHHHHHH	28.86	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERL1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EPF1_ARATH	EPF1	physical	22241782
EPF2_ARATH	EPF2	physical	22241782
ERL1_ARATH	ERL1	physical	22241782
MSBP1_ARATH	MSBP1	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.