EAF1_SCHPO - dbPTM
EAF1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EAF1_SCHPO
UniProt AC A0ZWU1
Protein Name Ell1-associated factor 1
Gene Name eaf1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 251
Subcellular Localization Nucleus .
Protein Description Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with ell1. Acts as a transcriptional transactivator of ell1 elongation activities..
Protein Sequence MNSLQKGSYKVIPGSSFSKNSNGLLSIKYNFIPESVDPSRRGVLEKAQEAYRLRLPSTFDDDRPHIFEGSCQRARNVDCVLIFNAKTKTFTLEHIDEIARLNALRNPKVSKTVPSNAITQSDNSQISESKSTSQSAVTTNSTRRKEKELEASKDGKIKPSSSNTRYPAISSKGPITTDTNDEPDMEVMELDDFAKELELGFDQEFNSIDDPSTVSQTASKPISLRGLSSQERDYASSAQAEGISSASEDED
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
244PhosphorylationSAQAEGISSASEDED
HHHHCCCCCCCCCCC		30.6124763107
245PhosphorylationAQAEGISSASEDED-
HHHCCCCCCCCCCC-		33.6224763107
247PhosphorylationAEGISSASEDED---
HCCCCCCCCCCC---		47.7528889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EAF1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EAF1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EAF1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SDS23_SCHPOsds23genetic
22681890
YIN2_SCHPOSPAC1705.02genetic
22681890
YCGK_SCHPOSPCC16C4.20cgenetic
22681890
SEC7B_SCHPOsec72genetic
22681890
SPP1_SCHPOspf1genetic
22681890
PPR2_SCHPOppr2genetic
22681890
YE98_SCHPOerp2genetic
22681890
RL27A_SCHPOrpl2701genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
EMC1_SCHPOemc1genetic
22681890
YOX1_SCHPOyox1genetic
22681890
OMH6_SCHPOomh6genetic
22681890
AMT2_SCHPOamt2genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EAF1_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247, AND MASSSPECTROMETRY.

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