DIF1_YEAST - dbPTM
DIF1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DIF1_YEAST
UniProt AC O13577
Protein Name Damage-regulated import facilitator 1
Gene Name DIF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 133
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase..
Protein Sequence MDAQLEWASSLVPKRQLQQQQQQQEQQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHETMVNGSKRRL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
74PhosphorylationQPGVIRDYSSVIVPQ
CCCCCCCCCEEECCC		7.9427017623
75PhosphorylationPGVIRDYSSVIVPQF
CCCCCCCCEEECCCC		23.5527017623
76PhosphorylationGVIRDYSSVIVPQFT
CCCCCCCEEECCCCC		15.0527017623
102PhosphorylationPMLINQRTMSTEASS
CCEECCCCCCCCCHH		13.0023749301
104PhosphorylationLINQRTMSTEASSLE
EECCCCCCCCCHHHH		23.6018851834
105PhosphorylationINQRTMSTEASSLEK
ECCCCCCCCCHHHHC		25.4218851834
108PhosphorylationRTMSTEASSLEKWDV
CCCCCCCHHHHCCCC		29.2618851834
109PhosphorylationTMSTEASSLEKWDVA
CCCCCCHHHHCCCCC		47.8218851834
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DIF1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DIF1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DIF1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RIR2_YEASTRNR2physical
18851834
RIR4_YEASTRNR4physical
18851834
WTM1_YEASTWTM1genetic
18838542
KA122_YEASTKAP122genetic
18838542
SML1_YEASTSML1genetic
18838542
ATR_YEASTMEC1genetic
18838542
CDK1_YEASTCDC28genetic
27708008
CDC7_YEASTCDC7genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
CDC11_YEASTCDC11genetic
27708008
MCM1_YEASTMCM1genetic
27708008
BUR1_YEASTSGV1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DIF1_YEAST

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Related Literatures of Post-Translational Modification

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