DCD2B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DCD2B_HUMAN
• UniProt AC: A2VCK2
• Protein Name: Doublecortin domain-containing protein 2B
• Gene Name: DCDC2B
• Organism: Homo sapiens (Human).
• Sequence Length: 349
• Protein Sequence: MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	AAKRVVVYRNGDPFF CCCEEEEEECCCCCC	6.17	25884760
35	Phosphorylation	VTQRRFPTMEAFLCE EEECCCCCHHHHHHH	25.57	-
58	Phosphorylation	LAVRALYTPCHGHPV HHHHHHCCCCCCCCC	21.93	27966365
102	Phosphorylation	GKDPGGKSCRLQGPP CCCCCCCCCCCCCCC	14.03	-
129	Phosphorylation	QLPAGAPSYIHVFRN CCCCCCCCEEEEEEC	35.86	-
130	Phosphorylation	LPAGAPSYIHVFRNG CCCCCCCEEEEEECC	8.25	-
217	Phosphorylation	YLELLVPSPSLPRGC CEEEECCCCCCCCCC	21.46	20363803
219	Phosphorylation	ELLVPSPSLPRGCWQ EEECCCCCCCCCCCC	56.17	20363803
247	Phosphorylation	QGHRAQVTQPSPKEP CCCCCCCCCCCCCCC	23.76	24719451
250	Phosphorylation	RAQVTQPSPKEPDRI CCCCCCCCCCCCCCC	38.49	27966365
260	Phosphorylation	EPDRIKPSAFYARPQ CCCCCCCCCCCCCCC	26.47	24719451
263	Phosphorylation	RIKPSAFYARPQQTI CCCCCCCCCCCCCCC	11.04	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DCD2B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DCD2B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DCD2B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAT3_HUMAN	FAT3	physical	28514442
FAT4_HUMAN	FAT4	physical	28514442
PSMG4_HUMAN	PSMG4	physical	28514442
FHL2_HUMAN	FHL2	physical	28514442
HSP7C_HUMAN	HSPA8	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
PCD20_HUMAN	PCDH20	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.