CHD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHD2_HUMAN
• UniProt AC: O14647
• Protein Name: Chromodomain-helicase-DNA-binding protein 2
• Gene Name: CHD2
• Organism: Homo sapiens (Human).
• Sequence Length: 1828
• Subcellular Localization: Nucleus. Binds to myogenic gene promoters..
• Protein Description: DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity)..
• Protein Sequence: MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	Phosphorylation	SESAGSKSQPVLPEA HHCCCCCCCCCCHHH	41.22	28188228
83	Acetylation	QPVLPEAKEKPASKK CCCCHHHHCCCCCHH	65.69	18528967
85	Acetylation	VLPEAKEKPASKKER CCHHHHCCCCCHHHH	45.22	7430811
90	Acetylation	KEKPASKKERIADVK HCCCCCHHHHHHHHH	50.13	7430821
103	Phosphorylation	VKKMWEEYPDVYGVR HHHHHHHCCCHHCCC	8.01	25262027
107	Phosphorylation	WEEYPDVYGVRRSNR HHHCCCHHCCCCCCC	19.79	25262027
125	Sumoylation	EPSRFNIKEEASSGS CCCCCCCCHHHCCCC	51.08	-
125	Sumoylation	EPSRFNIKEEASSGS CCCCCCCCHHHCCCC	51.08	17000644
125 (in isoform 3)	Sumoylation	-	51.08	-
129	Phosphorylation	FNIKEEASSGSESGS CCCCHHHCCCCCCCC	38.21	29255136
130	Phosphorylation	NIKEEASSGSESGSP CCCHHHCCCCCCCCC	54.08	29255136
132	Phosphorylation	KEEASSGSESGSPKR CHHHCCCCCCCCCCH	30.45	29255136
134	Phosphorylation	EASSGSESGSPKRRG HHCCCCCCCCCCHHH	46.39	23663014
136	Phosphorylation	SSGSESGSPKRRGQR CCCCCCCCCCHHHHH	36.21	30631047
156	Phosphorylation	EKWKQEPSEDEQEQG HHHHCCCCHHHHHHC	57.85	29507054
164	Phosphorylation	EDEQEQGTSAESEPE HHHHHHCCCCCCCHH	25.18	28450419
164 (in isoform 3)	Phosphorylation	-	25.18	-
165	Phosphorylation	DEQEQGTSAESEPEQ HHHHHCCCCCCCHHH	36.54	28450419
168	Phosphorylation	EQGTSAESEPEQKKV HHCCCCCCCHHHHHH	59.16	28450419
207	Phosphorylation	GKRKKQDSSDEDDDD CCCCCCCCCCCCCCC	36.88	23927012
207 (in isoform 3)	Phosphorylation	-	36.88	-
208	Phosphorylation	KRKKQDSSDEDDDDD CCCCCCCCCCCCCCC	53.99	23927012
208 (in isoform 3)	Phosphorylation	-	53.99	-
231	Phosphorylation	RRAAKNVSYKEDDDF HHHHHCCCCCCCCCC	39.62	22210691
232	Phosphorylation	RAAKNVSYKEDDDFE HHHHCCCCCCCCCCC	17.70	24144214
240	Phosphorylation	KEDDDFETDSDDLIE CCCCCCCCCHHHHHH	40.57	22617229
240 (in isoform 3)	Phosphorylation	-	40.57	-
242	Phosphorylation	DDDFETDSDDLIEMT CCCCCCCHHHHHHHH	40.21	22617229
242 (in isoform 3)	Phosphorylation	-	40.21	-
249	Phosphorylation	SDDLIEMTGEGVDEQ HHHHHHHHCCCCCCC	21.20	25849741
262	Phosphorylation	EQQDNSETIEKVLDS CCCCCHHHHHHHHHH	33.97	-
269	Phosphorylation	TIEKVLDSRLGKKGA HHHHHHHHCCCCCCC	25.83	-
277	Phosphorylation	RLGKKGATGASTTVY CCCCCCCCCCCEEEE	41.78	23401153
280	Phosphorylation	KKGATGASTTVYAIE CCCCCCCCEEEEEEE	26.42	23401153
281	Phosphorylation	KGATGASTTVYAIEA CCCCCCCEEEEEEEE	21.53	30206219
282	Phosphorylation	GATGASTTVYAIEAN CCCCCCEEEEEEEEC	14.71	30206219
284	Phosphorylation	TGASTTVYAIEANGD CCCCEEEEEEEECCC	10.36	23401153
293	Phosphorylation	IEANGDPSGDFDTEK EEECCCCCCCCCCCC	56.59	23401153
298	Phosphorylation	DPSGDFDTEKDEGEI CCCCCCCCCCCCCCE	44.95	23401153
354	Ubiquitination	EIKQWLGKVSPEDVE HHHHHHCCCCHHHHH	37.05	29967540
377	Phosphorylation	ASELNKQYQIVERVI HHHHHHHHHHHHHEE	11.21	28152594
388	Phosphorylation	ERVIAVKTSKSTLGQ HHEEECCCCCCCCCC	34.49	23312004
389	Phosphorylation	RVIAVKTSKSTLGQT HEEECCCCCCCCCCC	20.92	23312004
391	Phosphorylation	IAVKTSKSTLGQTDF EECCCCCCCCCCCCC	28.73	25954137
392	Phosphorylation	AVKTSKSTLGQTDFP ECCCCCCCCCCCCCC	38.35	25954137
396	Phosphorylation	SKSTLGQTDFPAHSR CCCCCCCCCCCCCCC	37.50	25954137
402	Phosphorylation	QTDFPAHSRKPAPSN CCCCCCCCCCCCCCC	44.07	23312004
408	Phosphorylation	HSRKPAPSNEPEYLC CCCCCCCCCCCHHHH	56.80	25954137
422	Phosphorylation	CKWMGLPYSECSWED HHHCCCCHHHCCCCC	23.34	29759185
423	Phosphorylation	KWMGLPYSECSWEDE HHCCCCHHHCCCCCH	30.13	29759185
435	Ubiquitination	EDEALIGKKFQNCID CCHHHHCHHHHHHHH	43.34	-
436	Ubiquitination	DEALIGKKFQNCIDS CHHHHCHHHHHHHHH	47.14	-
443	Phosphorylation	KFQNCIDSFHSRNNS HHHHHHHHHHHCCCC	12.63	29496963
472	Ubiquitination	PRFVALKKQPAYLGG CCEEEEECCCCCCCC	63.46	29967540
487	Phosphorylation	ENLELRDYQLEGLNW CCCCCCCCCCCCCHH	14.46	29083192
498	Phosphorylation	GLNWLAHSWCKNNSV CCHHHHHHHHHCCCE	28.67	29083192
596	Phosphorylation	FNALITTYEILLKDK HHHHEEEHHHHHCCC	7.72	22817900
623	Sumoylation	VDEAHRLKNDDSLLY CCHHHHCCCCCCHHH	59.28	-
623	Sumoylation	VDEAHRLKNDDSLLY CCHHHHCCCCCCHHH	59.28	17000644
623	Ubiquitination	VDEAHRLKNDDSLLY CCHHHHCCCCCCHHH	59.28	-
627	Phosphorylation	HRLKNDDSLLYKTLI HHCCCCCCHHHHHHH	24.12	28555341
631	Ubiquitination	NDDSLLYKTLIDFKS CCCCHHHHHHHCHHC	36.50	29967540
637	Ubiquitination	YKTLIDFKSNHRLLI HHHHHCHHCCCCEEE	46.75	29967540
702	Sumoylation	PFLLRRVKKDVEKSL HHHHHHHHHHHHHCC	41.25	-
702	Sumoylation	PFLLRRVKKDVEKSL HHHHHHHHHHHHHCC	41.25	17000644
708	Phosphorylation	VKKDVEKSLPAKVEQ HHHHHHHCCCHHHHH	26.53	-
722	Phosphorylation	QILRVEMSALQKQYY HHHHHHHHHHHHHHH	16.60	24670416
728	Phosphorylation	MSALQKQYYKWILTR HHHHHHHHHHHHHHH	17.66	-
729	Phosphorylation	SALQKQYYKWILTRN HHHHHHHHHHHHHHC	9.43	26657352
734	Phosphorylation	QYYKWILTRNYKALA HHHHHHHHHCHHHHH	14.03	26657352
737	Phosphorylation	KWILTRNYKALAKGT HHHHHHCHHHHHCCC	8.37	22817900
744	Phosphorylation	YKALAKGTRGSTSGF HHHHHCCCCCCCCHH	31.02	29083192
747	Phosphorylation	LAKGTRGSTSGFLNI HHCCCCCCCCHHHHH	18.99	17192257
748	Phosphorylation	AKGTRGSTSGFLNIV HCCCCCCCCHHHHHH	35.38	29083192
749	Phosphorylation	KGTRGSTSGFLNIVM CCCCCCCCHHHHHHH	29.28	29083192
766	Phosphorylation	KKCCNHCYLIKPPEE HHHCCCCEEECCCHH	12.15	-
816	Sulfoxidation	RVLIFSQMVRMLDIL CEEEHHHHHHHHHHH	1.68	31801345
828	Phosphorylation	DILAEYLTIKHYPFQ HHHHHHHHCCCCCHH	27.38	-
840	Phosphorylation	PFQRLDGSIKGEIRK CHHHCCCCCCHHHHH	22.31	-
842	Sumoylation	QRLDGSIKGEIRKQA HHCCCCCCHHHHHHH	52.79	-
842	Sumoylation	QRLDGSIKGEIRKQA HHCCCCCCHHHHHHH	52.79	17000644
913	Phosphorylation	QKKQVNIYRLVTKGT CCCCEEEEEEECCCC	7.84	22210691
917	Phosphorylation	VNIYRLVTKGTVEEE EEEEEEECCCCHHHH	28.48	27732954
958	Phosphorylation	LENNSGRSNSNPFNK HCCCCCCCCCCCCCH	48.40	23312004
960	Phosphorylation	NNSGRSNSNPFNKEE CCCCCCCCCCCCHHH	47.31	23312004
969	Phosphorylation	PFNKEELTAILKFGA CCCHHHHHHHHHHCH	18.22	23312004
988	Phosphorylation	KELEGEESEPQEMDI HHHCCCCCCCCCCCH	50.72	27732954
1010	Phosphorylation	ETRENEVSTSATDEL HHHCCCCCCHHHHHH	15.51	30576142
1011	Phosphorylation	TRENEVSTSATDELL HHCCCCCCHHHHHHH	27.79	30576142
1012	Phosphorylation	RENEVSTSATDELLS HCCCCCCHHHHHHHH	22.97	17192257
1014	Phosphorylation	NEVSTSATDELLSQF CCCCCHHHHHHHHHH	29.76	28348404
1019	Phosphorylation	SATDELLSQFKVANF HHHHHHHHHHCCCCC	46.31	-
1028	Phosphorylation	FKVANFATMEDEEEL HCCCCCCCCCCHHHH	19.56	23312004
1062	Ubiquitination	VEEEERQKELEEIYM HHHHHHHHHHHHHHH	71.18	-
1068	Phosphorylation	QKELEEIYMLPRIRS HHHHHHHHHHHHHHH	8.90	21945579
1075	O-linked_Glycosylation	YMLPRIRSSTKKAQT HHHHHHHHCCCCCCC	39.73	30620550
1076	O-linked_Glycosylation	MLPRIRSSTKKAQTN HHHHHHHCCCCCCCC	34.10	30620550
1082	Phosphorylation	SSTKKAQTNDSDSDT HCCCCCCCCCCCCCH	45.94	30576142
1085	Phosphorylation	KKAQTNDSDSDTESK CCCCCCCCCCCHHHH	40.87	28176443
1087	Phosphorylation	AQTNDSDSDTESKRQ CCCCCCCCCHHHHHH	50.84	25849741
1089	Phosphorylation	TNDSDSDTESKRQAQ CCCCCCCHHHHHHHH	46.22	28176443
1091	Phosphorylation	DSDSDTESKRQAQRS CCCCCHHHHHHHHHH	34.92	28176443
1101	Phosphorylation	QAQRSSASESETEDS HHHHHCCCCCCCCCC	43.53	30576142
1103	Phosphorylation	QRSSASESETEDSDD HHHCCCCCCCCCCCC	47.53	28348404
1105	Phosphorylation	SSASESETEDSDDDK HCCCCCCCCCCCCCC	55.14	28348404
1108	Phosphorylation	SESETEDSDDDKKPK CCCCCCCCCCCCCCH	36.39	30576142
1122	Phosphorylation	KRRGRPRSVRKDLVE HHCCCCCCHHHHHHC	29.02	29214152
1132	Phosphorylation	KDLVEGFTDAEIRRF HHHHCCCCHHHHHHH	45.19	-
1141	Ubiquitination	AEIRRFIKAYKKFGL HHHHHHHHHHHHHCC	42.84	-
1165	Ubiquitination	RDAELVDKSVADLKR HCHHHHCCHHHHHHH	39.07	29967540
1209	Phosphorylation	PGKRRGPTIKISGVQ CCCCCCCEEEEEEEE	37.41	-
1213	Phosphorylation	RGPTIKISGVQVNVK CCCEEEEEEEEEEHH	28.10	23401153
1285	Sumoylation	YGNWELIKTDPELKL CCCEEECCCCCCCCC	60.54	-
1285	Sumoylation	YGNWELIKTDPELKL CCCEEECCCCCCCCC	60.54	17000644
1295	Ubiquitination	PELKLTDKILPVETD CCCCCCCCCCCCCCC	40.69	29967540
1338	Acetylation	VTGGEEAKLKKRKPR CCCCHHHHHHCCCCC	65.21	19824139
1347	Sumoylation	KKRKPRVKKENKVPR HCCCCCCCCCCCCCC	56.50	-
1347	Sumoylation	KKRKPRVKKENKVPR HCCCCCCCCCCCCCC	56.50	17000644
1356	Sumoylation	ENKVPRLKEEHGIEL CCCCCCHHHHHCCCC	63.44	-
1356	Sumoylation	ENKVPRLKEEHGIEL CCCCCCHHHHHCCCC	63.44	17000644
1364	Phosphorylation	EEHGIELSSPRHSDN HHHCCCCCCCCCCCC	26.04	23401153
1365	Phosphorylation	EHGIELSSPRHSDNP HHCCCCCCCCCCCCC	38.28	29255136
1369	Phosphorylation	ELSSPRHSDNPSEEG CCCCCCCCCCCCCCC	40.12	29255136
1373	Phosphorylation	PRHSDNPSEEGEVKD CCCCCCCCCCCCCCC	55.31	29255136
1379	Sumoylation	PSEEGEVKDDGLEKS CCCCCCCCCCCCCCC	45.88	-
1379	Sumoylation	PSEEGEVKDDGLEKS CCCCCCCCCCCCCCC	45.88	17000644
1386	Phosphorylation	KDDGLEKSPMKKKQK CCCCCCCCCCHHHHH	22.35	29255136
1429	Phosphorylation	DKKEKPKSGDAKSSS CCCCCCCCCCCCCCC	50.89	-
1434	Phosphorylation	PKSGDAKSSSKSKRS CCCCCCCCCCCCCCC	41.38	-
1441	Phosphorylation	SSSKSKRSQGPVHIT CCCCCCCCCCCEEEE	43.13	18691976
1448	Phosphorylation	SQGPVHITAGSEPVP CCCCEEEEECCCCCC	15.30	-
1546	Methylation	KFTEFDARKLHKLYK CCCHHHHHHHHHHHH	43.86	-
1560	Phosphorylation	KMAHKKRSQEEEEQK HHHHHHCCHHHHHHH	51.31	30242111
1573	Phosphorylation	QKKKDDVTGGKKPFR HHHHHCCCCCCCCCC	47.41	24732914
1584	Phosphorylation	KPFRPEASGSSRDSL CCCCCCCCCCCHHHH	37.23	21406692
1586	Phosphorylation	FRPEASGSSRDSLIS CCCCCCCCCHHHHHH	21.50	21406692
1587	Phosphorylation	RPEASGSSRDSLISQ CCCCCCCCHHHHHHC	43.56	21406692
1590	Phosphorylation	ASGSSRDSLISQSHT CCCCCHHHHHHCCCC	26.88	25159151
1593	Phosphorylation	SSRDSLISQSHTSHN CCHHHHHHCCCCCCC	30.81	29449344
1595	Phosphorylation	RDSLISQSHTSHNLH HHHHHHCCCCCCCCC	23.18	29449344
1597	Phosphorylation	SLISQSHTSHNLHPQ HHHHCCCCCCCCCCC	36.61	29449344
1598	Phosphorylation	LISQSHTSHNLHPQK HHHCCCCCCCCCCCC	12.64	29449344
1633	Phosphorylation	HPNKRHFSNADRGDW CCCCCCCCCCCCCCC	25.61	27251275
1637	Methylation	RHFSNADRGDWQRER CCCCCCCCCCCHHHH	42.43	-
1685	Methylation	RRHMDAHRSGSYRPN CCCCCHHHCCCCCCC	44.42	-
1686	Phosphorylation	RHMDAHRSGSYRPNN CCCCHHHCCCCCCCC	23.40	27251275
1688	Phosphorylation	MDAHRSGSYRPNNMS CCHHHCCCCCCCCCC	21.15	24719451
1695	Phosphorylation	SYRPNNMSRKRPYDQ CCCCCCCCCCCCCCC	36.45	-
1715	Phosphorylation	DHRGHRDYYDRHHHD CCCCCCCCHHHCCCC	13.76	25367160
1716	Phosphorylation	HRGHRDYYDRHHHDS CCCCCCCHHHCCCCC	15.70	25367160
1728	Phosphorylation	HDSKRRRSDEFRPQN CCCCCCCCCCCCCCC	39.41	30266825
1736	Phosphorylation	DEFRPQNYHQQDFRR CCCCCCCCCHHHHHH	8.85	20873877
1745	Phosphorylation	QQDFRRMSDHRPAMG HHHHHHHCCCCCCCC	28.58	29214152
1753	Phosphorylation	DHRPAMGYHGQGPSD CCCCCCCCCCCCCCC	6.95	28634298
1762	Phosphorylation	GQGPSDHYRSFHTDK CCCCCCCCHHCCCCC	16.97	-
1764	Phosphorylation	GPSDHYRSFHTDKLG CCCCCCHHCCCCCCC	17.76	23312004
1767	Phosphorylation	DHYRSFHTDKLGEYK CCCHHCCCCCCCCCC	32.58	23312004
1773	Phosphorylation	HTDKLGEYKQPLPPL CCCCCCCCCCCCCCC	17.08	23312004
1785	Phosphorylation	PPLHPAVSDPRSPPS CCCCCCCCCCCCCCC	43.96	30266825
1789	Phosphorylation	PAVSDPRSPPSQKSP CCCCCCCCCCCCCCC	46.69	30266825
1792	Phosphorylation	SDPRSPPSQKSPHDS CCCCCCCCCCCCCCC	54.33	23401153
1795	Phosphorylation	RSPPSQKSPHDSKSP CCCCCCCCCCCCCCC	21.60	23927012
1799	Phosphorylation	SQKSPHDSKSPLDHR CCCCCCCCCCCCCCC	31.81	23927012
1801	Phosphorylation	KSPHDSKSPLDHRSP CCCCCCCCCCCCCCH	34.35	23401153
1807	Phosphorylation	KSPLDHRSPLERSLE CCCCCCCCHHHHHHH	30.34	28355574
1821	Phosphorylation	EQKNNPDYNWNVRKT HHHCCCCCCCCCCCC	24.27	18691976
1828	Phosphorylation	YNWNVRKT------- CCCCCCCC-------	33.02	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRIM1_HUMAN	MID2	physical	25416956
THAP1_HUMAN	THAP1	physical	25416956
TEKT1_HUMAN	TEKT1	physical	25416956
TRI41_HUMAN	TRIM41	physical	25416956
BEND7_HUMAN	BEND7	physical	25416956
TRI41_HUMAN	TRIM41	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 615369: Epileptic encephalopathy, childhood-onset (EEOC)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-240 AND SER-242, ANDMASS SPECTROMETRY.
PubMed: 18669648

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-240; SER-242; SER-747;SER-1012; SER-1801 AND SER-1807, AND MASS SPECTROMETRY.
PubMed: 18691976