| UniProt ID | TEKT1_HUMAN | |
|---|---|---|
| UniProt AC | Q969V4 | |
| Protein Name | Tektin-1 | |
| Gene Name | TEKT1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 418 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. | |
| Protein Description | Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.. | |
| Protein Sequence | MAKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGVWAGGLRPDAVC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 50 | Ubiquitination | RLVDEIEKTTRKSQS HHHHHHHHHHHHCHH | 61.94 | - | |
| 106 | Acetylation | EKALETLKEPLHITE HHHHHHCCCCHHHHH | 65.78 | 25038526 | |
| 118 | Phosphorylation | ITETCLAYREKRIGI HHHHHHHHHHHHHCC | 13.32 | - | |
| 249 | Phosphorylation | VDRILSQTANDLRKQ HHHHHHHHHHHHHHH | 24.85 | - | |
| 249 | O-linked_Glycosylation | VDRILSQTANDLRKQ HHHHHHHHHHHHHHH | 24.85 | 30379171 | |
| 262 | Phosphorylation | KQCDVVDTAFKNGLK HHCCHHHHHHHCCCC | 23.53 | 29083192 | |
| 271 | Phosphorylation | FKNGLKDTKDARDKL HHCCCCCCHHHHHHH | 29.27 | 29083192 | |
| 396 | Phosphorylation | LCMQMRKSIPLRDGE HHHHCCCCCCCCCCC | 21.05 | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TEKT1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TEKT1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TEKT1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TEKT1_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
