CDKC2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDKC2_ARATH
• UniProt AC: Q8W4P1
• Protein Name: Cyclin-dependent kinase C-2
• Gene Name: CDKC-2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 513
• Protein Sequence: MAAAAFGQLNLEEPPPIWGSRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESNWPGVSKMPWYNQMKSSRPLKRRVREIYRHFDRHALELLEKMLVLDPSQRICAKDALDAEYFWTDPLPCDPKSLPTYESSHEFQTKKKRQQMRHNEEAAKKQKLQHPQQQHSRLPPQQHGVGQSHAAPLWPAGPNHPMNNNAPPPQIPAGGHYYGGKPRGGAPVPNRYPPSGNQTGGYNNQSRGGYSSGAYPPQGRGAPYGAGPRGPSGGYGVGPPNYSQGGGQYGGSGGSGRGQNPMGGARNQQYGWQP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	EQIGEGTYGQVYMAK HHHCCCCCEEEEEEE	19.20	-
93	Phosphorylation	IHLKEIVTSPGRDRD EEEEEEECCCCCCCC	34.56	19880383
94	Phosphorylation	HLKEIVTSPGRDRDD EEEEEECCCCCCCCC	17.92	23111157
188	Phosphorylation	ADFGLARSYSHDHTG CHHCCCCCCCCCCCC	25.94	23776212
189	Phosphorylation	DFGLARSYSHDHTGN HHCCCCCCCCCCCCC	12.41	23776212
190	Phosphorylation	FGLARSYSHDHTGNL HCCCCCCCCCCCCCC	24.56	23776212
194	Phosphorylation	RSYSHDHTGNLTNRV CCCCCCCCCCCCCEE	33.55	23776212
198	Phosphorylation	HDHTGNLTNRVITLW CCCCCCCCCEEEEEE	25.61	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDKC2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDKC2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDKC2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STAD7_ARATH	SSI2	physical	20706207
IF2B_ARATH	EIF2 BETA	physical	20706207
SUMO3_ARATH	SUMO3	physical	20855607
MPK3_ARATH	MPK3	physical	25464831
NRPB1_ARATH	NRPB1	physical	25464831
CCT15_ARATH	AT5G45190	genetic	17468259
CCT13_ARATH	CYCT1;3	physical	17468259
CCT14_ARATH	CYCT1;4	physical	17468259
CCT15_ARATH	AT5G45190	physical	17468259

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.