dbPTM

CCT14_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CCT14_ARATH
UniProt AC	Q8GYM6
Protein Name	Cyclin-T1-4
Gene Name	CYCT1-4
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	541
Subcellular Localization
Protein Description
Protein Sequence	MAGVLAGDCSFGESGVSSYSRNSNEKQDEVARWYFGRKEIEENSPSRLDSIDLKKETYLRKSYCTFLQDLGMRLKVPQVTIATAIIFCHRFFIRQSHARNDRRTIATVCMFLAGKVEETPRPLKDVIVVSYEIIHKKDPTTAQKIKQKEVYEQQKELILNGEKIVLSTLGFDFNVYHPYKPLVEAIKKFKVAQNALAQVAWNFVNDGLRTSLCLQFKPHHIAAGAIFLAAKFLKVKLPSDGEKVWWQEFDVTPRQLEDVSNQMLELYEQNRVPASQVSEVESSVGGGSAHHVGSRPSARLTHEHSNSDNLGGSTKATQNRSNDNGSGEAGSVITEQKGERDTETKDSMHTESHPAHKSRSGVEAPGEDKIEKAGAHFPEDDKSRIVGTADVTVSQSPKDIKMFRDKVKAKLEAKKVQGEKTRKKDLVDEDDLIERELEDVELAVEDDKDIQNKSSMGTEHGEILDGNNLVVNTEEGEMIDDVSSTMPSRKRKMESPCEKQLGEGKRRHDNSENVEEGQKTNPGGSSHSYGDREPRRHSQER

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	VSSYSRNSNEKQDEV CCCCCCCCCCCHHHH	45.30	25561503
307	Phosphorylation	LTHEHSNSDNLGGST CCCCCCCCCCCCCCC	30.78	25561503
388	Phosphorylation	DKSRIVGTADVTVSQ CCCCEEEEEEEEECC	14.59	23776212
392	Phosphorylation	IVGTADVTVSQSPKD EEEEEEEEECCCHHH	18.26	23776212
394	Phosphorylation	GTADVTVSQSPKDIK EEEEEEECCCHHHHH	18.64	23776212
396	Phosphorylation	ADVTVSQSPKDIKMF EEEEECCCHHHHHHH	26.81	30291188
495	Phosphorylation	SRKRKMESPCEKQLG CCCHHCCCHHHHHHC	31.21	25561503
525	Phosphorylation	QKTNPGGSSHSYGDR CCCCCCCCCCCCCCC	30.69	25561503
526	Phosphorylation	KTNPGGSSHSYGDRE CCCCCCCCCCCCCCC	21.52	25561503
528	Phosphorylation	NPGGSSHSYGDREPR CCCCCCCCCCCCCCC	32.53	25561503
529	Phosphorylation	PGGSSHSYGDREPRR CCCCCCCCCCCCCCC	20.02	25561503
538	Phosphorylation	DREPRRHSQER---- CCCCCCCCCCC----	31.74	27545962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CCT14_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CCT14_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CCT14_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CCT14_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CCT14_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-396, AND MASSSPECTROMETRY.	19376835 [Abstract]