| UniProt ID | CAV_DROME | |
|---|---|---|
| UniProt AC | Q95RV2 | |
| Protein Name | Telomere-binding protein cav {ECO:0000303|PubMed:12510197} | |
| Gene Name | cav {ECO:0000303|PubMed:12510197} | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 345 | |
| Subcellular Localization | Nucleus . Chromosome, telomere . Enriched at interphase, polytene and mitotic chromosome telomeres. Localized predominantly at telomeres and diffusely throughout regions of pericentric heterochromatin. | |
| Protein Description | Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.. | |
| Protein Sequence | MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of CAV_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CAV_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CAV_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CAV_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HP1_DROME | Su(var)205 | physical | 14605208 | |
| ATM_DROME | tefu | genetic | 16710445 | |
| SXL_DROME | Sxl | genetic | 21695246 | |
| HP1_DROME | Su(var)205 | physical | 20057353 | |
| HP1_DROME | Su(var)205 | physical | 11408576 | |
| HP1_DROME | Su(var)205 | physical | 12826664 | |
| HP1_DROME | Su(var)205 | physical | 19190990 | |
| HP1_DROME | Su(var)205 | physical | 26110638 | |
| ORC1_DROME | Orc1 | physical | 12826664 | |
| ORC6_DROME | Orc6 | physical | 11408576 | |
| ORC6_DROME | Orc6 | physical | 12826664 | |
| ORC2_DROME | Orc2 | physical | 11408576 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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