BRL3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BRL3_ARATH
• UniProt AC: Q9LJF3
• Protein Name: Receptor-like protein kinase BRI1-like 3
• Gene Name: BRL3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1164
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Binds brassinolide. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. May be involved in cell growth and vascular differentiation..
• Protein Sequence: MKQQWQFLILCLLVLFLTVDSRGRRLLSDDVNDTALLTAFKQTSIKSDPTNFLGNWRYGSGRDPCTWRGVSCSSDGRVIGLDLRNGGLTGTLNLNNLTALSNLRSLYLQGNNFSSGDSSSSSGCSLEVLDLSSNSLTDSSIVDYVFSTCLNLVSVNFSHNKLAGKLKSSPSASNKRITTVDLSNNRFSDEIPETFIADFPNSLKHLDLSGNNVTGDFSRLSFGLCENLTVFSLSQNSISGDRFPVSLSNCKLLETLNLSRNSLIGKIPGDDYWGNFQNLRQLSLAHNLYSGEIPPELSLLCRTLEVLDLSGNSLTGQLPQSFTSCGSLQSLNLGNNKLSGDFLSTVVSKLSRITNLYLPFNNISGSVPISLTNCSNLRVLDLSSNEFTGEVPSGFCSLQSSSVLEKLLIANNYLSGTVPVELGKCKSLKTIDLSFNALTGLIPKEIWTLPKLSDLVMWANNLTGGIPESICVDGGNLETLILNNNLLTGSLPESISKCTNMLWISLSSNLLTGEIPVGIGKLEKLAILQLGNNSLTGNIPSELGNCKNLIWLDLNSNNLTGNLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLEHFPMVHSCPKTRIYSGMTMYMFSSNGSMIYLDLSYNAVSGSIPLGYGAMGYLQVLNLGHNLLTGTIPDSFGGLKAIGVLDLSHNDLQGFLPGSLGGLSFLSDLDVSNNNLTGPIPFGGQLTTFPLTRYANNSGLCGVPLPPCSSGSRPTRSHAHPKKQSIATGMSAGIVFSFMCIVMLIMALYRARKVQKKEKQREKYIESLPTSGSSSWKLSSVHEPLSINVATFEKPLRKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTGQGDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQVDTENDSLDEFLLKETPLVEESRDKEP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	N-linked_Glycosylation	RLLSDDVNDTALLTA CCCCCCCCCHHHHHH	48.16	-
89	Phosphorylation	DLRNGGLTGTLNLNN ECCCCCCCCEEECCH	31.25	27545962
91	Phosphorylation	RNGGLTGTLNLNNLT CCCCCCCEEECCHHH	13.77	27545962
96	N-linked_Glycosylation	TGTLNLNNLTALSNL CCEEECCHHHHHHHH	41.77	-
98	Phosphorylation	TLNLNNLTALSNLRS EEECCHHHHHHHHCC	27.89	27545962
101	Phosphorylation	LNNLTALSNLRSLYL CCHHHHHHHHCCEEE	31.21	27545962
112	N-linked_Glycosylation	SLYLQGNNFSSGDSS CEEECCCCCCCCCCC	45.03	-
156	N-linked_Glycosylation	CLNLVSVNFSHNKLA HCHHHEEECCCCCCC	25.79	-
212	N-linked_Glycosylation	HLDLSGNNVTGDFSR CEECCCCCCCCCHHH	35.93	-
227	N-linked_Glycosylation	LSFGLCENLTVFSLS HCEECCCCEEEEEEC	39.76	-
257	N-linked_Glycosylation	CKLLETLNLSRNSLI CCHHHHCCCCCCCCC	43.31	-
362	N-linked_Glycosylation	NLYLPFNNISGSVPI CEEECCCCCCCCCCE	30.13	-
373	N-linked_Glycosylation	SVPISLTNCSNLRVL CCCEEEECCCCCEEE	32.29	-
461	N-linked_Glycosylation	DLVMWANNLTGGIPE HHHHHHHHCCCCCCH	31.09	-
532	N-linked_Glycosylation	LAILQLGNNSLTGNI EEEEECCCCCCCCCC	43.43	-
558	N-linked_Glycosylation	WLDLNSNNLTGNLPG EEECCCCCCCCCCCH	38.51	-
638	N-linked_Glycosylation	TMYMFSSNGSMIYLD EEEEEECCCCEEEEE	45.41	-
722	N-linked_Glycosylation	DLDVSNNNLTGPIPF CCCCCCCCCCCCCCC	43.14	-
743	N-linked_Glycosylation	FPLTRYANNSGLCGV EECEECCCCCCCCCC	33.98	-
775	Phosphorylation	PKKQSIATGMSAGIV CCHHHHCCCCCHHHH	31.57	19880383
847	Phosphorylation	EKPLRKLTFAHLLEA CHHHHHHHHHHHHHH	23.08	-
855	Phosphorylation	FAHLLEATNGFSADS HHHHHHHCCCCCCCC	26.88	-
931	Phosphorylation	GEERLLVYEYMKYGS CCCEEHEEEHHHHCC	11.00	-
1020	Phosphorylation	LDTHLSVSTLAGTPG HHHCCCHHHHCCCCC	17.83	-
1021	Phosphorylation	DTHLSVSTLAGTPGY HHCCCHHHHCCCCCC	20.62	24243849
1025	Phosphorylation	SVSTLAGTPGYVPPE CHHHHCCCCCCCCHH	14.13	24243849
1028	Phosphorylation	TLAGTPGYVPPEYYQ HHCCCCCCCCHHHHH	15.81	-
1099	Phosphorylation	PELVTDKSGDVELLH HHHCCCCCCCEEHHH	42.93	15308754
1140	Phosphorylation	KELVQVDTENDSLDE HHHHCCCCCCCCHHH	37.52	15308754
1144	Phosphorylation	QVDTENDSLDEFLLK CCCCCCCCHHHHHHH	49.67	15308754

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BRL3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BRL3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BRL3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BRL3_ARATH	BRL3	physical	24064770
BAK1_ARATH	BAK1	physical	24064770
BRL1_ARATH	BRL1	physical	24064770
Y4523_ARATH	BSK1	physical	24064770
FERON_ARATH	FER	physical	24064770
CDPK3_ARATH	CDPK6	physical	24064770
CDPKW_ARATH	CPK32	physical	24064770
VHAA2_ARATH	VHA-A2	physical	24064770
PMA2_ARATH	HA2	physical	24064770
DRP1E_ARATH	DL1E	physical	24064770

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.