DRP1E_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DRP1E_ARATH
• UniProt AC: Q9FNX5
• Protein Name: Dynamin-related protein 1E
• Gene Name: DRP1E
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 624
• Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, phragmoplast. Microtubule-associated and localized in the forming cell plate during cytokinesis.
• Protein Description: Microtubule-associated force-producing protein that is targeted to the tubulo-vesicular network of the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with an implication in vesicular trafficking, polar cell expansion, and other aspects of plant growth and development..
• Protein Sequence: MTTMESLIGLVNRIQRACTVLGDYGGGTGSNAFNSLWEALPTVAVVGGQSSGKSSVLESIVGRDFLPRGSGIVTRRPLVLQLHKTDDGTEEYAEFLHLPKKQFTDFALVRREIQDETDRITGKNKQISPVPIHLSIYSPNVVNLTLIDLPGLTKVAVEGQPETIAEDIESMVRTYVDKPNCIILAISPANQDIATSDAIKLAKDVDPTGERTFGVLTKLDLMDKGTNALEVLEGRSYRLQHPWVGIVNRSQADINKNVDMMLARRKEREYFDTSPDYGHLASKMGSEYLAKLLSKHLESVIRTRIPSILSLINKSIEELERELDRMGRPVAVDAGAQLYTILEMCRAFDKIFKEHLDGGRPGGDRIYGVFDNQLPAALKKLPFDRHLSLQSVKKIVSEADGYQPHLIAPEQGYRRLIEGALGYFRGPAEASVDAVHYVLKELVRKSISETEELKRFPSLQVELAAAANSSLEKFREESKKSVIRLVDMESAYLTAEFFRKLPQEIERPVTNSKNQTASPSSATLDQYGDGHFRRIASNVSAYVNMVSDTLRNTIPKACVYCQVRQAKLALLNYFYSQISKREGKQLGQLLDEDPALMDRRLECAKRLELYKKARDEIDAVAWVR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MTTMESLIG ------CCHHHHHHH	34.55	22223895
2	Phosphorylation	------MTTMESLIG ------CCHHHHHHH	34.55	24924143
70	Phosphorylation	RDFLPRGSGIVTRRP CCCCCCCCCCEECCC	26.99	28011693
226	Phosphorylation	LDLMDKGTNALEVLE HHHHCCCCCHHHHHC	24.06	19880383
458	Phosphorylation	EELKRFPSLQVELAA HHHHCCCCHHHHHHH	28.81	28011693
516	Phosphorylation	VTNSKNQTASPSSAT CCCCCCCCCCCCCCC	38.20	25561503
518	Phosphorylation	NSKNQTASPSSATLD CCCCCCCCCCCCCHH	28.80	30291188
520	Phosphorylation	KNQTASPSSATLDQY CCCCCCCCCCCHHHH	30.06	23111157
521	Phosphorylation	NQTASPSSATLDQYG CCCCCCCCCCHHHHC	28.76	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DRP1E_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DRP1E_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DRP1E_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of DRP1E_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.