BRL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BRL1_ARATH
• UniProt AC: Q9ZWC8
• Protein Name: Serine/threonine-protein kinase BRI1-like 1
• Gene Name: BRL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1166
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Receptor with a serine/threonine-protein kinase activity. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. Binds brassinolide. May be involved in cell growth and vascular differentiation..
• Protein Sequence: MKQRWLLVLILCFFTTSLVMGIHGKHLINDDFNETALLLAFKQNSVKSDPNNVLGNWKYESGRGSCSWRGVSCSDDGRIVGLDLRNSGLTGTLNLVNLTALPNLQNLYLQGNYFSSGGDSSGSDCYLQVLDLSSNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTHNNLSGDFSDLSFGICGNLTFFSLSQNNLSGDKFPITLPNCKFLETLNISRNNLAGKIPNGEYWGSFQNLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNYLSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLSSNGFTGNVPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDLSFNELTGPIPKEIWMLPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLLTGSIPESISRCTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDLNSNNLTGDLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLERLPMVHSCPATRIYSGMTMYTFSANGSMIYFDISYNAVSGFIPPGYGNMGYLQVLNLGHNRITGTIPDSFGGLKAIGVLDLSHNNLQGYLPGSLGSLSFLSDLDVSNNNLTGPIPFGGQLTTFPVSRYANNSGLCGVPLRPCGSAPRRPITSRIHAKKQTVATAVIAGIAFSFMCFVMLVMALYRVRKVQKKEQKREKYIESLPTSGSCSWKLSSVPEPLSINVATFEKPLRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEEDESLDEFSLKETPLVEESRDKEP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	N-linked_Glycosylation	HLINDDFNETALLLA CCCCCCCCHHHHHHH	53.34	-
97	N-linked_Glycosylation	TGTLNLVNLTALPNL CCEEEEEECCCCCCC	34.54	-
157	N-linked_Glycosylation	CSNLVSVNISNNKLV CCCCEEEECCCCEEE	25.19	-
212	N-linked_Glycosylation	YLDLTHNNLSGDFSD EEECCCCCCCCCHHH	28.16	-
227	N-linked_Glycosylation	LSFGICGNLTFFSLS CCEECCCCEEEEECC	31.34	-
237	N-linked_Glycosylation	FFSLSQNNLSGDKFP EEECCCCCCCCCCCC	28.13	-
257	N-linked_Glycosylation	CKFLETLNISRNNLA CCEECEECCCCCCCC	37.29	-
362	N-linked_Glycosylation	YLYVAYNNISGSVPI EEEEEECCCCCCCCE	19.68	-
373	N-linked_Glycosylation	SVPISLTNCSNLRVL CCCEEEECCCCCEEE	32.29	-
451	N-linked_Glycosylation	KEIWMLPNLSDLVMW HHHHCCCCHHHHHHH	48.49	-
461	N-linked_Glycosylation	DLVMWANNLTGTIPE HHHHHHHCCCCCCCC	31.09	-
521	N-linked_Glycosylation	KIPSGIGNLSKLAIL CCCCCCCHHHHEEEE	38.94	-
532	N-linked_Glycosylation	LAILQLGNNSLSGNV EEEEECCCCCCCCCC	43.43	-
558	N-linked_Glycosylation	WLDLNSNNLTGDLPG EEECCCCCCCCCCCH	38.51	-
638	N-linked_Glycosylation	TMYTFSANGSMIYFD EEEEEECCCCEEEEE	41.70	-
722	N-linked_Glycosylation	DLDVSNNNLTGPIPF CCCCCCCCCCCCCCC	43.14	-
743	N-linked_Glycosylation	FPVSRYANNSGLCGV EECHHHCCCCCCCCC	33.98	-
823	Phosphorylation	LPTSGSCSWKLSSVP CCCCCCCCEEECCCC	29.01	17317660
848	Phosphorylation	EKPLRKLTFAHLLEA CHHHHHHHHHHHHHH	23.08	-
856	Phosphorylation	FAHLLEATNGFSAET HHHHHHHCCCCCCEE	26.88	-
932	Phosphorylation	GEERLLVYEYMKWGS CHHEEEEEEHHHHCC	11.00	-
1022	Phosphorylation	LDTHLSVSTLAGTPG HHHCCCHHHHCCCCC	17.83	-
1023	Phosphorylation	DTHLSVSTLAGTPGY HHCCCHHHHCCCCCC	20.62	24243849
1027	Phosphorylation	SVSTLAGTPGYVPPE CHHHHCCCCCCCCHH	14.13	24243849
1030	Phosphorylation	TLAGTPGYVPPEYYQ HHCCCCCCCCHHHHH	15.81	-
1101	Phosphorylation	PELVTDKSGDVELFH HHHCCCCCCCEEHHH	42.93	15308754
1141	Phosphorylation	FKEMKADTEEDESLD HHHHHCCCCCCCCCC	46.24	15308754
1146	Phosphorylation	ADTEEDESLDEFSLK CCCCCCCCCCHHCCC	54.14	17317660
1151	Phosphorylation	DESLDEFSLKETPLV CCCCCHHCCCCCCCC	36.16	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BRL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BRL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BRL1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAK1_ARATH	BAK1	physical	24064770

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.