BNIPL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BNIPL_HUMAN
• UniProt AC: Q7Z465
• Protein Name: Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein
• Gene Name: BNIPL
• Organism: Homo sapiens (Human).
• Sequence Length: 357
• Protein Description: May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death..
• Protein Sequence: MGTIQEAGKKTDVGVREIAEAPELGAALRHGELELKEEWQDEEFPRLLPEEAGTSEDPEDPKGDSQAAAGTPSTLALCGQRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSDSEQLDSGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLHGSGGT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6 (in isoform 2)	Phosphorylation	-	56.38	25849741
6 (in isoform 3)	Phosphorylation	-	56.38	25849741
55	Phosphorylation	LPEEAGTSEDPEDPK CCCCCCCCCCCCCCC	38.80	22210691
71	Phosphorylation	DSQAAAGTPSTLALC CCCCCCCCHHHHHHC	14.89	24719451
73	Phosphorylation	QAAAGTPSTLALCGQ CCCCCCHHHHHHCCC	35.57	22210691
88	Phosphorylation	RPMRKRLSAPELRLS CCCCCCCCCCCHHHH	45.90	25849741
95	Phosphorylation	SAPELRLSLTKGPGN CCCCHHHHCCCCCCC	27.79	28102081
97	Phosphorylation	PELRLSLTKGPGNDG CCHHHHCCCCCCCCC	30.49	28102081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BNIPL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BNIPL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BNIPL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BCL2_HUMAN	BCL2	physical	12901880
BNIPL_HUMAN	BNIPL	physical	12901880
RHG01_HUMAN	ARHGAP1	physical	12901880
BNIP2_HUMAN	BNIP2	physical	12901880
B2CL1_HUMAN	BCL2L1	physical	12901880
ALR_HUMAN	GFER	physical	12681488
MIF_HUMAN	MIF	physical	12681488
ALR_HUMAN	GFER	physical	21988832
MIF_HUMAN	MIF	physical	21988832
NDKB_HUMAN	NME2	physical	21988832
P5CR1_HUMAN	PYCR1	physical	21988832
PXDN_HUMAN	PXDN	physical	21988832
RECQ5_HUMAN	RECQL5	physical	21988832
SNAPN_HUMAN	SNAPIN	physical	21988832
FKBP8_HUMAN	FKBP8	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.