BAP29_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BAP29_HUMAN
• UniProt AC: Q9UHQ4
• Protein Name: B-cell receptor-associated protein 29
• Gene Name: BCAP29
• Organism: Homo sapiens (Human).
• Sequence Length: 241
• Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein.
• Protein Description: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity)..
• Protein Sequence: MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLIVLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTLQWAAVA ------CCHHHHHHH	27.88	24043423
10	Phosphorylation	LQWAAVATFLYAEIG HHHHHHHHHHHHHHH	13.94	24043423
13	Phosphorylation	AAVATFLYAEIGLIL HHHHHHHHHHHHHHH	9.67	24043423
72	Ubiquitination	DAVREVRKYSSVHTI HHHHHHHHHCCCCEE	55.44	-
73	Phosphorylation	AVREVRKYSSVHTIE HHHHHHHHCCCCEEC	8.80	26437602
82	Phosphorylation	SVHTIEKSSTSRPDA CCCEECCCCCCCCCH	26.51	-
90	Phosphorylation	STSRPDAYEHTQMKL CCCCCCHHHHHHHHH	18.67	-
96	Ubiquitination	AYEHTQMKLFRSQRN HHHHHHHHHHHHHCC	34.36	21890473
122	Phosphorylation	LVLRRLVTLITQLAK HHHHHHHHHHHHHHH	19.62	29449344
125	Phosphorylation	RRLVTLITQLAKELS HHHHHHHHHHHHHHH	22.20	29449344
134	Malonylation	LAKELSNKGVLKTQA HHHHHHCCCCCHHHH	47.20	26320211
134	Ubiquitination	LAKELSNKGVLKTQA HHHHHHCCCCCHHHH	47.20	-
138	Ubiquitination	LSNKGVLKTQAENTN HHCCCCCHHHHHHHH	35.86	21890473
150	Ubiquitination	NTNKAAKKFMEENEK HHHHHHHHHHHHHHH	45.26	-
157	Malonylation	KFMEENEKLKRILKS HHHHHHHHHHHHHHH	71.53	26320211
157	Ubiquitination	KFMEENEKLKRILKS HHHHHHHHHHHHHHH	71.53	-
163	Ubiquitination	EKLKRILKSHGKDEE HHHHHHHHHCCCCHH	37.73	-
164	Phosphorylation	KLKRILKSHGKDEEC HHHHHHHHCCCCHHH	33.74	25849741
167	Ubiquitination	RILKSHGKDEECVLE HHHHHCCCCHHHHHH	57.45	-
186	Ubiquitination	KLVEDQEKLKTELRK HHHCCHHHHHHHHHH	50.04	-
206	Sulfoxidation	SKAQNDVMEMKMQSE HHHHHHHHHHHHHHH	4.67	30846556
208	Sulfoxidation	AQNDVMEMKMQSERL HHHHHHHHHHHHHHH	2.06	30846556
209	Ubiquitination	QNDVMEMKMQSERLS HHHHHHHHHHHHHHH	22.08	21890473
217	Ubiquitination	MQSERLSKEYDQLLK HHHHHHHHHHHHHHH	65.96	21890473
219	Phosphorylation	SERLSKEYDQLLKEH HHHHHHHHHHHHHHH	16.84	-
219 (in isoform 2)	Phosphorylation	-	16.84	27642862
224	Ubiquitination	KEYDQLLKEHSELQD HHHHHHHHHHHHHHH	63.07	-
232	Methylation	EHSELQDRLERGNKK HHHHHHHHHHHCHHC	26.03	-
247 (in isoform 2)	Phosphorylation	-		-
252 (in isoform 2)	Phosphorylation	-		-
254 (in isoform 2)	Phosphorylation	-		-
299 (in isoform 2)	Phosphorylation	-		21406692
318 (in isoform 2)	Phosphorylation	-		21406692

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BAP29_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BAP29_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BAP29_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAP31_HUMAN	BCAP31	physical	12886015
ATPO_HUMAN	ATP5O	physical	26344197
NACA2_HUMAN	NACA2	physical	26344197
PDIA1_HUMAN	P4HB	physical	26344197
RPN1_HUMAN	RPN1	physical	26344197
CACO2_HUMAN	CALCOCO2	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.