ASK20_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ASK20_ARATH
• UniProt AC: A8MQG7
• Protein Name: SKP1-like protein 20
• Gene Name: ASK20
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 352
• Subcellular Localization: Nucleus.
• Protein Description: Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity)..
• Protein Sequence: MSEGDLAVMKPETMKSYIWLQTADGSIQQVEQEVAMFCPMICQEVIQKGVGSSKNHAISLPQRVNPAMFSLILDYCRFHQLPGRSNKERKTYDERFIRMDTKRLCELTSAADSLQLKPLVDLTSRALARIIEGKNPEEIREIFHLPDDLTEEEKLEPLKNSMDDPRIRLLNRLYAKKRKELKERERLKNVEVEEHVDERSVDDLLSFINGRDHKAVKMSKGKKKKKKKKDQKIVSSNNIHDKESHDLRSKQQCVEEIGSSMREVPNLLSAEDDISTPNAGSEDEDIDDEIDPAMRELLDREVEDFAQRLNSNWVRSLGKERRPVHFSINGNGTTRRHTGMVSIWRPCMFTLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
269	Phosphorylation	REVPNLLSAEDDIST HHCHHHHCCCCCCCC	32.55	30407730
275	Phosphorylation	LSAEDDISTPNAGSE HCCCCCCCCCCCCCC	44.82	30407730
276	Phosphorylation	SAEDDISTPNAGSED CCCCCCCCCCCCCCC	22.39	30407730
281	Phosphorylation	ISTPNAGSEDEDIDD CCCCCCCCCCCCCCH	39.19	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ASK20_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ASK20_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ASK20_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ADO2_ARATH	LKP2	physical	15310821
FK122_ARATH	AT5G49000	physical	21798944
FB270_ARATH	AT5G39250	physical	21798944
FBK77_ARATH	HWS	physical	21798944
TCP14_ARATH	TCP14	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.