ART10_YEAST - dbPTM
ART10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ART10_YEAST
UniProt AC P18634
Protein Name Arrestin-related trafficking adapter 10
Gene Name ART10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 518
Subcellular Localization Cytoplasm .
Protein Description May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli..
Protein Sequence MAPKISISLNPPYNGEFYSSNDQMSGIVSLQLTKALSIRKISVILKGFSETLTKIDQEYMFQQNGMMMPGQDNKSFHTLMKFEQRVFPPDNVWNALDGSSKPFKVKPGSYNYSFQFDKFPRKPECLKNHTAKTVAFVTRSNARLPPTFNSHWQEFNKIDNLDLYFYSFGKVIYMVQVQLELGKSSSWFKPFHKLIREIETFEFIPEPKDLIIEPDEDDNEELNAFSNNSRGNSMVTNNEFFNSSNLKVPSKDVKVVNGVGYIKSDRNFSQANSILIENGDIRSRPVSSVTSTRQSTRLVNGMKVFPSTYKMGLPDGESNMRIEVRSRDLKQIYRKDYLFRSGSQNFDKVYVVMEGNIASLSKMQITPLKLQLNLLETTTYLSQGIANGNYSSLKLIEIDLNQLKSNKPLLDLNEIRENFDGSMFECELRLKDHPILRKLVFNEEDYRHRGNRLYSFKTCTIKRTFSLQLLIEWGINGIRKQSEVNIDPVQIFCQVREHVEAEALPRYVPPPTYTEMAS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
13PhosphorylationSISLNPPYNGEFYSS
EEEECCCCCCCCCCC		36.7419779198
18PhosphorylationPPYNGEFYSSNDQMS
CCCCCCCCCCCCCCC		13.5919779198
19PhosphorylationPYNGEFYSSNDQMSG
CCCCCCCCCCCCCCC		28.1719779198
118UbiquitinationNYSFQFDKFPRKPEC
ECEEECCCCCCCHHH		59.5623749301
122UbiquitinationQFDKFPRKPECLKNH
ECCCCCCCHHHHCCC		45.4622817900
127UbiquitinationPRKPECLKNHTAKTV
CCCHHHHCCCCCCEE		59.3423749301
226PhosphorylationNEELNAFSNNSRGNS
CHHHHHHCCCCCCCC		32.4628889911
229PhosphorylationLNAFSNNSRGNSMVT
HHHHCCCCCCCCCCC		45.9027214570
233PhosphorylationSNNSRGNSMVTNNEF
CCCCCCCCCCCCCCC		19.9021551504
236PhosphorylationSRGNSMVTNNEFFNS
CCCCCCCCCCCCCCC		24.5521551504
247UbiquitinationFFNSSNLKVPSKDVK
CCCCCCCCCCCCCCE		57.2423749301
251UbiquitinationSNLKVPSKDVKVVNG
CCCCCCCCCCEEECC		61.5424961812
254UbiquitinationKVPSKDVKVVNGVGY
CCCCCCCEEECCEEE		51.0723749301
263UbiquitinationVNGVGYIKSDRNFSQ
ECCEEEECCCCCHHH		37.5123749301
269PhosphorylationIKSDRNFSQANSILI
ECCCCCHHHCCEEEE		31.7523749301
273PhosphorylationRNFSQANSILIENGD
CCHHHCCEEEEECCC		23.0623749301
287PhosphorylationDIRSRPVSSVTSTRQ
CCCCCCCCCCCCCCC		23.0528889911
290PhosphorylationSRPVSSVTSTRQSTR
CCCCCCCCCCCCCCC		26.7423749301
291PhosphorylationRPVSSVTSTRQSTRL
CCCCCCCCCCCCCCC		21.3123749301
295PhosphorylationSVTSTRQSTRLVNGM
CCCCCCCCCCCCCCE		16.5327017623
303UbiquitinationTRLVNGMKVFPSTYK
CCCCCCEEECCCEEE		41.9623749301
404UbiquitinationEIDLNQLKSNKPLLD
EEEHHHHHCCCCCCC		42.0723749301
407UbiquitinationLNQLKSNKPLLDLNE
HHHHHCCCCCCCHHH		44.1024961812
438UbiquitinationKDHPILRKLVFNEED
CCCHHHHHHCCCHHH		45.6223749301
457UbiquitinationGNRLYSFKTCTIKRT
CCCEEEEEEEEEEEE		36.4323749301
462UbiquitinationSFKTCTIKRTFSLQL
EEEEEEEEEEEEHHH		27.5122817900
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ART10_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ART10_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
JSN1_YEASTJSN1physical
10688190
RSP5_YEASTRSP5physical
18719252
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
GPR1_YEASTGPR1genetic
27708008
MGA2_YEASTMGA2genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
FEN1_YEASTRAD27genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ART10_YEAST

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Related Literatures of Post-Translational Modification

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