ARR4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARR4_ARATH
• UniProt AC: O82798
• Protein Name: Two-component response regulator ARR4
• Gene Name: ARR4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 259
• Subcellular Localization: Nucleus .
• Protein Description: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling. Modulates red light signaling through its interaction with the phytochrome B photoreceptor..
• Protein Sequence: MARDGGVSCLRRSEMMSVGGIGGIESAPLDLDEVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDNEKASAEFDRLKVDLIITDYCMPGMTGYELLKKIKESSNFREVPVVIMSSENVLTRIDRCLEEGAQDFLLKPVKLADVKRLRSHLTKDVKLSNGNKRKLPEDSSSVNSSLPPPSPPLTISPESSPPLTVSTESSDSSPPLSPVEIFSTSPLSSPIDDEDDDVLTSSSEESPIRRQKMRSPGLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
95	Phosphorylation	KVDLIITDYCMPGMT EEEEEEECCCCCCCC	24.99	-
159	Phosphorylation	ADVKRLRSHLTKDVK HHHHHHHHHHCCCEE	27.69	19880383
162	Phosphorylation	KRLRSHLTKDVKLSN HHHHHHHCCCEECCC	21.55	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARR4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARR4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARR4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHYB_ARATH	PHYB	physical	17545225
AHP1_ARATH	AHP1	physical	17545225
PHYB_ARATH	PHYB	physical	11691995
REMO_ARATH	AT2G45820	physical	9771897
ZWIP2_ARATH	NTT	physical	18642946
P2C38_ARATH	AT3G12620	physical	18642946
AHP1_ARATH	AHP1	physical	10930573
AHP1_ARATH	AHP1	physical	25643735
AHP1_ARATH	AHP1	physical	16965536
AHP2_ARATH	AHP2	physical	16965536

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.