ZSWM7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSWM7_HUMAN
• UniProt AC: Q19AV6
• Protein Name: Zinc finger SWIM domain-containing protein 7
• Gene Name: ZSWIM7
• Organism: Homo sapiens (Human).
• Sequence Length: 140
• Subcellular Localization: Nucleus .
• Protein Description: Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents..
• Protein Sequence: MAVVLPAVVEELLSEMAAAVQESARIPDEYLLSLKFLFGSSATQALDLVDRQSITLISSPSGRRVYQVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	AVVEELLSEMAAAVQ HHHHHHHHHHHHHHH	37.64	24043423
23	Phosphorylation	MAAAVQESARIPDEY HHHHHHHHCCCCHHH	13.03	24043423
30	Phosphorylation	SARIPDEYLLSLKFL HCCCCHHHHHHHHHH	21.96	24043423
33	Phosphorylation	IPDEYLLSLKFLFGS CCHHHHHHHHHHHCC	27.24	24719451
66	Phosphorylation	SPSGRRVYQVLGSSS CCCCCCEEEECCCCC	7.35	29496907
110	Phosphorylation	CKHLLAVYLSQVMRT HHHHHHHHHHHHHHH	8.60	-
112	Phosphorylation	HLLAVYLSQVMRTCQ HHHHHHHHHHHHHHH	11.75	-
129	Phosphorylation	SVSDKQLTDILLMEK CCCHHHHHHHHHHHH	20.64	-
136	Ubiquitination	TDILLMEKKQEA--- HHHHHHHHHHCC---	45.88	21906983
137	Ubiquitination	DILLMEKKQEA---- HHHHHHHHHCC----	39.81	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSWM7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSWM7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSWM7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SWAP1_HUMAN	SWSAP1	physical	21965664
EFTU_HUMAN	TUFM	physical	21965664
GRP78_HUMAN	HSPA5	physical	21965664
GRP75_HUMAN	HSPA9	physical	21965664
H2B2E_HUMAN	HIST2H2BE	physical	21965664
RA51D_HUMAN	RAD51D	physical	21965664
XRCC3_HUMAN	XRCC3	physical	21965664
SWAP1_HUMAN	SWSAP1	physical	25659377

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.