ZN695_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN695_HUMAN
• UniProt AC: Q8IW36
• Protein Name: Zinc finger protein 695
• Gene Name: ZNF695
• Organism: Homo sapiens (Human).
• Sequence Length: 515
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGLLAFRDVALEFSPEEWECLDPAQRSLYRDVMLENYRNLISLGEDSFNMQFLFHSLAMSKPELIICLEARKEPWNVNTEKTARHSVLSSYLTEDILPEQGLQVSFQKVMLRRYERCCLEKLRLRNDWEIVGEWKGQKASYNGLDLCSATTHSKNFQCNKCVKGFSKFANLNKCKISHTGEKPFKCKECGNVSCMSLIMTQQQRIHIGENPYQCKKCGKAFNECSCFTDCKRIHVGEKHCKCEECNNIFKSCSSLAVVEKNHTEKKTYRCEECGKAFNLCSVLTKHKKIHTGEKPYKCEECGKSFKLFPYLTQHKRIHSREKPYKCEECGKVFKLLSYLTQHRRIHTGEKTFRCEECGKAFNQSSHLTEHRRIHTGEKPYKCEECGKAFTWFSYLIQHKRIHTGQKPYKCEECGKAFTWFSYLTQHKRIHTGEKPYKCDECGKAFNWFSYLTNHKRIHTGEKPYKCEECGKAFGQSSHLSKHKTIHTREKPYKCEECGKAFNHSAQLAVHEKTHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Ubiquitination	IICLEARKEPWNVNT EEEEECCCCCCCCCC	75.16	-
79	Phosphorylation	KEPWNVNTEKTARHS CCCCCCCCHHHHHHH	34.28	28348404
121	Acetylation	YERCCLEKLRLRNDW HHHHHHHHHHCCCCC	26.42	30593883
121	Ubiquitination	YERCCLEKLRLRNDW HHHHHHHHHHCCCCC	26.42	-
150	Phosphorylation	GLDLCSATTHSKNFQ CEECCCCCCCCCCCC	14.56	29759185
151	Phosphorylation	LDLCSATTHSKNFQC EECCCCCCCCCCCCC	24.70	29759185
153	Phosphorylation	LCSATTHSKNFQCNK CCCCCCCCCCCCCCH	27.48	-
291	Phosphorylation	TKHKKIHTGEKPYKC HHCCCCCCCCCCEEC	50.97	29496963
296	Phosphorylation	IHTGEKPYKCEECGK CCCCCCCEECCCCCC	39.06	-
297	Sumoylation	HTGEKPYKCEECGKS CCCCCCEECCCCCCC	43.63	-
297	Ubiquitination	HTGEKPYKCEECGKS CCCCCCEECCCCCCC	43.63	-
325	Sumoylation	HSREKPYKCEECGKV HCCCCCCCHHHHHHH	43.63	-
337	Phosphorylation	GKVFKLLSYLTQHRR HHHHHHHHHHHHCCC	28.65	26699800
338	Phosphorylation	KVFKLLSYLTQHRRI HHHHHHHHHHHCCCC	17.46	26699800
340	Phosphorylation	FKLLSYLTQHRRIHT HHHHHHHHHCCCCCC	17.69	26699800
375	Phosphorylation	TEHRRIHTGEKPYKC CCCCCCCCCCCCEEC	44.67	29496963
380	Phosphorylation	IHTGEKPYKCEECGK CCCCCCCEECCHHHH	39.06	-
381	Sumoylation	HTGEKPYKCEECGKA CCCCCCEECCHHHHH	43.63	-
381	Ubiquitination	HTGEKPYKCEECGKA CCCCCCEECCHHHHH	43.63	-
409	Sumoylation	HTGQKPYKCEECGKA CCCCCCEECCCCCCH	43.63	-
431	Phosphorylation	TQHKRIHTGEKPYKC HCCCCCCCCCCCEEC	44.67	29496963
437	Ubiquitination	HTGEKPYKCDECGKA CCCCCCEECCCCCHH	43.68	-
459	Phosphorylation	TNHKRIHTGEKPYKC HCCCCCCCCCCCCCC	44.67	29496963
464	Phosphorylation	IHTGEKPYKCEECGK CCCCCCCCCCHHHHH	39.06	-
465	Ubiquitination	HTGEKPYKCEECGKA CCCCCCCCCHHHHHH	43.63	-
465	Sumoylation	HTGEKPYKCEECGKA CCCCCCCCCHHHHHH	43.63	-
487	Phosphorylation	SKHKTIHTREKPYKC HCCCCCCCCCCCCCC	36.35	-
493	Sumoylation	HTREKPYKCEECGKA CCCCCCCCCHHHHHH	43.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN695_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN695_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN695_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZY11A_HUMAN	ZYG11A	physical	28514442
SAV1_HUMAN	SAV1	physical	28514442
TIF1A_HUMAN	TRIM24	physical	28514442
HECD1_HUMAN	HECTD1	physical	28514442
STK3_HUMAN	STK3	physical	28514442
TIF1B_HUMAN	TRIM28	physical	28514442
ACTB_HUMAN	ACTB	physical	28514442
TBB3_HUMAN	TUBB3	physical	28514442
STK4_HUMAN	STK4	physical	28514442
TBA1A_HUMAN	TUBA1A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.