ZN558_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN558_HUMAN
• UniProt AC: Q96NG5
• Protein Name: Zinc finger protein 558
• Gene Name: ZNF558
• Organism: Homo sapiens (Human).
• Sequence Length: 402
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAVILPSTAAPSSLFPASQQKGHTQGGELVNELLTSWLRGLVTFEDVAVEFTQEEWALLDPAQRTLYRDVMLENCRNLASLGCRVNKPSLISQLEQDKKVVTEERGILPSTCPDLETLLKAKWLTPKKNVFRKEQSKGVKTERSHRGVKLNECNQCFKVFSTKSNLTQHKRIHTGEKPYDCSQCGKSFSSRSYLTIHKRIHNGEKPYECNHCGKAFSDPSSLRLHLRIHTGEKPYECNQCFHVFRTSCNLKSHKRIHTGENHHECNQCGKAFSTRSSLTGHNSIHTGEKPYECHDCGKTFRKSSYLTQHVRTHTGEKPYECNECGKSFSSSFSLTVHKRIHTGEKPYECSDCGKAFNNLSAVKKHLRTHTGEKPYECNHCGKSFTSNSYLSVHKRIHNRWI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
175	Phosphorylation	TQHKRIHTGEKPYDC CCCCCCCCCCCCCCH	44.67	20736484
231	Phosphorylation	RLHLRIHTGEKPYEC EEEEEEECCCCCCCC	44.67	28111955
247	Ubiquitination	QCFHVFRTSCNLKSH CCEEEEEECCCCCCC	26.60	-
287	Phosphorylation	TGHNSIHTGEKPYEC CCCCCEECCCCCEEE	45.42	-
313	Phosphorylation	YLTQHVRTHTGEKPY HHHHHHHHCCCCCCE	23.77	28348404
315	Phosphorylation	TQHVRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	29496963
318	Ubiquitination	VRTHTGEKPYECNEC HHHCCCCCCEECCCC	55.00	-
331	Phosphorylation	ECGKSFSSSFSLTVH CCCCCCCCEEEEEEE	33.13	-
343	Phosphorylation	TVHKRIHTGEKPYEC EEECEEECCCCCEEC	44.67	21712546
346	Ubiquitination	KRIHTGEKPYECSDC CEEECCCCCEECCCH	55.00	-
369	Phosphorylation	AVKKHLRTHTGEKPY HHHHHHHHCCCCCCE	30.10	-
371	Phosphorylation	KKHLRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN558_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN558_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN558_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ALBU_HUMAN	ALB	physical	26186194
APOA1_HUMAN	APOA1	physical	26186194
A1AT_HUMAN	SERPINA1	physical	26186194
RCBT2_HUMAN	RCBTB2	physical	26186194
APOA1_HUMAN	APOA1	physical	28514442
A1AT_HUMAN	SERPINA1	physical	28514442
RCBT2_HUMAN	RCBTB2	physical	28514442
FRIL_HUMAN	FTL	physical	28514442
ALBU_HUMAN	ALB	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.