ZN471_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN471_HUMAN
• UniProt AC: Q9BX82
• Protein Name: Zinc finger protein 471
• Gene Name: ZNF471
• Organism: Homo sapiens (Human).
• Sequence Length: 626
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MNVEVVKVMPQDLVTFKDVAIDFSQEEWQWMNPAQKRLYRSMMLENYQSLVSLGLCISKPYVISLLEQGREPWEMTSEMTRSPFSDWESIYVTQELPLKQFMYDDACMEGITSYGLECSTFEENWKWEDLFEKQMGSHEMFSKKEIITHKETITKETEFKYTKFGKCIHLENIEESIYNHTSDKKSFSKNSMVIKHKKVYVGKKLFKCNECDKTFTHSSSLTVHFRIHTGEKPYACEECGKAFKQRQHLAQHHRTHTGEKLFECKECRKAFKQSEHLIQHQRIHTGEKPYKCKECRKAFRQPAHLAQHQRIHTGEKPYECKECGKAFSDGSSFARHQRCHTGKRPYECIECGKAFRYNTSFIRHWRSYHTGEKPFNCIDCGKAFSVHIGLILHRRIHTGEKPYKCGVCGKTFSSGSSRTVHQRIHTGEKPYECDICGKDFSHHASLTQHQRVHSGEKPYECKECGKAFRQNVHLVSHLRIHTGEKPYECKECGKAFRISSQLATHQRIHTGEKPYECIECGNAFKQRSHLAQHQKTHTGEKPYECNECGKAFSQTSNLTQHQRIHTGEKPYKCTECGKAFSDSSSCAQHQRLHTGQRPYQCFECGKAFRRKLSLICHQRSHTGEEP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
137	Phosphorylation	LFEKQMGSHEMFSKK HHHHHCCCCCCCCHH	15.78	-
142	Phosphorylation	MGSHEMFSKKEIITH CCCCCCCCHHEEEEC	41.32	-
186	Phosphorylation	NHTSDKKSFSKNSMV CCCCCCCCCCCCCEE	40.26	26074081
188	Phosphorylation	TSDKKSFSKNSMVIK CCCCCCCCCCCEEEE	37.71	26074081
189	Acetylation	SDKKSFSKNSMVIKH CCCCCCCCCCEEEEE	51.54	7378687
191	Phosphorylation	KKSFSKNSMVIKHKK CCCCCCCCEEEEECE	20.40	26074081
197	Acetylation	NSMVIKHKKVYVGKK CCEEEEECEEEECCE	38.64	7378697
198	Acetylation	SMVIKHKKVYVGKKL CEEEEECEEEECCEE	38.22	7378705
229	Phosphorylation	TVHFRIHTGEKPYAC EEEEEEECCCCCEEH	44.67	28111955
255	Phosphorylation	HLAQHHRTHTGEKLF HHHHHCCCCCCHHHC	21.31	-
257	Phosphorylation	AQHHRTHTGEKLFEC HHHCCCCCCHHHCCC	46.56	-
285	Phosphorylation	IQHQRIHTGEKPYKC HHHCCCCCCCCCCCC	44.67	29496963
313	Phosphorylation	AQHQRIHTGEKPYEC HHHCCCCCCCCCCCC	44.67	29496963
321	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHCCCCC	44.06	-
321	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHCCCCC	44.06	-
357	Phosphorylation	ECGKAFRYNTSFIRH ECCCEEECCHHHHHC	19.15	24425749
360	Phosphorylation	KAFRYNTSFIRHWRS CEEECCHHHHHCHHH	18.29	24425749
398	Phosphorylation	ILHRRIHTGEKPYKC EEECCCCCCCCCEEC	44.67	29496963
411	Phosphorylation	KCGVCGKTFSSGSSR ECCCCCCEECCCCCC	17.65	-
416	Phosphorylation	GKTFSSGSSRTVHQR CCEECCCCCCEEEEE	20.70	-
426	Phosphorylation	TVHQRIHTGEKPYEC EEEEEEECCCCCEEC	44.67	28111955
462	Sumoylation	GEKPYECKECGKAFR CCCCCCHHHHHHHHH	44.06	-
462	Sumoylation	GEKPYECKECGKAFR CCCCCCHHHHHHHHH	44.06	-
482	Phosphorylation	VSHLRIHTGEKPYEC EEEEEEECCCCCEEC	44.67	29496963
490	Sumoylation	GEKPYECKECGKAFR CCCCEECCHHHCCEE	44.06	-
490	Sumoylation	GEKPYECKECGKAFR CCCCEECCHHHCCEE	44.06	-
510	Phosphorylation	ATHQRIHTGEKPYEC HHCCCCCCCCCCCEE	44.67	28111955
536	Phosphorylation	HLAQHQKTHTGEKPY HHHHCCCCCCCCCCC	20.35	28348404
538	Phosphorylation	AQHQKTHTGEKPYEC HHCCCCCCCCCCCCC	52.87	29496963
541	Ubiquitination	QKTHTGEKPYECNEC CCCCCCCCCCCCCCC	55.00	-
566	Phosphorylation	TQHQRIHTGEKPYKC CCCCEECCCCCCEEC	44.67	29496963

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN471_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN471_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN471_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZN471_HUMAN	ZNF471	physical	16189514
ZN471_HUMAN	ZNF471	physical	25416956
CAR14_HUMAN	CARD14	physical	25416956
COG7_HUMAN	COG7	physical	25416956
HAUS1_HUMAN	HAUS1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.