ZN211_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN211_HUMAN
• UniProt AC: Q13398
• Protein Name: Zinc finger protein 211
• Gene Name: ZNF211
• Organism: Homo sapiens (Human).
• Sequence Length: 564
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MLGFPPGRPQLPVQLRPQTRMATALRDPASGSVTFEDVAVYFSWEEWDLLDEAQKHLYFDVMLENFALTSSLGCWCGVEHEETPSEQRISGERVPQFRTSKEGSSSQNADSCEICCLVLRDILHLAEHQGTNCGQKLHTCGKQFYISANLQQHQRQHITEAPFRSYVDTASFTQSCIVHVSEKPFTCREIRKDFLANMRFLHQDATQTGEKPNNSNKCAVAFYSGKSHHNWGKCSKAFSHIDTLVQDQRILTREGLFECSKCGKACTRRCNLIQHQKVHSEERPYECNECGKFFTYYSSFIIHQRVHTGERPYACPECGKSFSQIYSLNSHRKVHTGERPYECGECGKSFSQRSNLMQHRRVHTGERPYECSECGKSFSQNFSLIYHQRVHTGERPHECNECGKSFSRSSSLIHHRRLHTGERPYECSKCGKSFKQSSSFSSHRKVHTGERPYVCGECGKSFSHSSNLKNHQRVHTGERPVECSECSKSFSCKSNLIKHLRVHTGERPYECSECGKSFSQSSSLIQHRRVHTGKRPYQCSQCGKSFGCKSVLIQHQRVHIGEKP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11 (in isoform 3)	Phosphorylation	-	5.07	26546556
159	Phosphorylation	QHQRQHITEAPFRSY HHHHHCCCCCCCHHH	24.78	25072903
165	Phosphorylation	ITEAPFRSYVDTASF CCCCCCHHHCCCCCE	29.86	25072903
166	Phosphorylation	TEAPFRSYVDTASFT CCCCCHHHCCCCCEE	9.70	25072903
169	Phosphorylation	PFRSYVDTASFTQSC CCHHHCCCCCEECCE	17.73	25072903
171	Phosphorylation	RSYVDTASFTQSCIV HHHCCCCCEECCEEE	30.80	25072903
173	Phosphorylation	YVDTASFTQSCIVHV HCCCCCEECCEEEEE	19.65	25072903
175	Phosphorylation	DTASFTQSCIVHVSE CCCCEECCEEEEECC	11.62	25072903
181	Phosphorylation	QSCIVHVSEKPFTCR CCEEEEECCCCEEHH	25.65	25072903
206	Phosphorylation	RFLHQDATQTGEKPN CCCCCCHHHCCCCCC	34.65	28348404
208	Phosphorylation	LHQDATQTGEKPNNS CCCCHHHCCCCCCCC	42.84	28348404
211	Ubiquitination	DATQTGEKPNNSNKC CHHHCCCCCCCCCCE	55.16	-
308	Phosphorylation	IIHQRVHTGERPYAC EEEEECCCCCCCCCC	37.57	-
326	Phosphorylation	GKSFSQIYSLNSHRK CCCHHHHHCCCCCCC	10.24	27067055
327	Phosphorylation	KSFSQIYSLNSHRKV CCHHHHHCCCCCCCE	23.78	27067055
330	Phosphorylation	SQIYSLNSHRKVHTG HHHHCCCCCCCEECC	29.93	27067055
333	Ubiquitination	YSLNSHRKVHTGERP HCCCCCCCEECCCCC	32.70	-
336	Phosphorylation	NSHRKVHTGERPYEC CCCCCEECCCCCCCC	43.66	28674419
341	Phosphorylation	VHTGERPYECGECGK EECCCCCCCCCCCCC	30.03	24719451
348	Methylation	YECGECGKSFSQRSN CCCCCCCCCHHHHHC	61.05	23644510
349	Phosphorylation	ECGECGKSFSQRSNL CCCCCCCCHHHHHCH	18.53	24719451
364	Phosphorylation	MQHRRVHTGERPYEC HHCCCCCCCCCCEEC	37.57	27251275
369	Phosphorylation	VHTGERPYECSECGK CCCCCCCEECCCCCC	35.47	-
372	Phosphorylation	GERPYECSECGKSFS CCCCEECCCCCCCHH	24.79	27251275
407	Phosphorylation	NECGKSFSRSSSLIH CCCCCCCCCCCCCEE	38.04	17081983
409	Phosphorylation	CGKSFSRSSSLIHHR CCCCCCCCCCCEECC	24.07	23312004
410	Phosphorylation	GKSFSRSSSLIHHRR CCCCCCCCCCEECCC	28.22	23312004
411	Phosphorylation	KSFSRSSSLIHHRRL CCCCCCCCCEECCCC	32.37	23312004
416	Methylation	SSSLIHHRRLHTGER CCCCEECCCCCCCCC	28.79	24396467
417	Methylation	SSLIHHRRLHTGERP CCCEECCCCCCCCCC	26.85	24396475
435	Sumoylation	SKCGKSFKQSSSFSS CCCCCCHHCCCCCCC	57.26	-
435	Sumoylation	SKCGKSFKQSSSFSS CCCCCCHHCCCCCCC	57.26	-
448	Phosphorylation	SSHRKVHTGERPYVC CCCCCCCCCCCCEEC	43.66	-
469	Ubiquitination	FSHSSNLKNHQRVHT CCCCCCCCCCCCEEC	57.54	-
493	Sumoylation	CSKSFSCKSNLIKHL CCCCCCCCCHHHHHE	40.98	-
493	Sumoylation	CSKSFSCKSNLIKHL CCCCCCCCCHHHHHE	40.98	-
493	Ubiquitination	CSKSFSCKSNLIKHL CCCCCCCCCHHHHHE	40.98	-
498	Ubiquitination	SCKSNLIKHLRVHTG CCCCHHHHHEEECCC	39.49	-
504	Phosphorylation	IKHLRVHTGERPYEC HHHEEECCCCCCEEC	37.57	27251275
509	Phosphorylation	VHTGERPYECSECGK ECCCCCCEECCCCCC	35.47	28258704
512	Phosphorylation	GERPYECSECGKSFS CCCCEECCCCCCCCC	24.79	28258704
517	Phosphorylation	ECSECGKSFSQSSSL ECCCCCCCCCCCCHH	18.53	28258704
521	Phosphorylation	CGKSFSQSSSLIQHR CCCCCCCCCHHHHHC	22.24	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN211_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN211_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN211_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMRCD_HUMAN	SMARCAD1	physical	28514442
TRI37_HUMAN	TRIM37	physical	28514442
NT5D3_HUMAN	NT5DC3	physical	28514442
UBP34_HUMAN	USP34	physical	28514442
STRN4_HUMAN	STRN4	physical	28514442
EHMT2_HUMAN	EHMT2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.