dbPTM

ZER1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZER1_DROME
UniProt AC	Q9W0E8
Protein Name	Protein zer-1 homolog
Gene Name	CG12084
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	793
Subcellular Localization
Protein Description	Probably acts as target recruitment subunit in an E3 ubiquitin ligase complex CG12084-cul-2-elongin BC..
Protein Sequence	MSCKVRLMEDGSLDEEPLTLKEIAYQKLCNNLDIISSHRPDGQRGLNPGIVLPNEICDGFLENYQRFNRPLDDSVIRLFEDTHRTSLKIVNLRNSTLSSIGLETLMRHKLFALSLWYCDMISVGSHHLLAHYGDSLRSLELGISSHLLQYAEPNEKEPVDFQLTCPHLRRLVLNGVVMHHRLQFAHLHDLGHLDLTSCVLANFSLEALGSLPNLHTLILFNVWPIANQLHAICCLRRLCTLDISISSSGNGHGTYDLPDQTLEMLMDNLRHLTHLDISGTNLAGNGVATKESTTTSGMQQSPKMEQHFALTDIPGLASRTQRPLQFLGLYHTAHWACKRHDIPALEVAGDANEQQILTAARYYHDRPVLLTRVLNDLYHLFRFENCKDIHTALDVVLSAMDRHLKFKHMQISGSATLFYIVKGRDRSKFGALLRNHIIRTLLNGMEMHITDDTMLRNGYLTLTQFHMPVDVLFEYERLIKILLHGVSKTEQEGFVQRIAIYLLNTLACQVDGRQKLFLGELGVVSTMFTLIKDRLTRSVFDDVMEVAWSTMWNVTDETAINCKRFLDGRGMEYFLKCLHTFPDRDELLRNMMGLLGNVAEVKWLRPKLMTQEFIEVFARLLDSLSDGIEVGGASASVVARVREREMASANHAYLRFQVSYNAAGVLAHIASDGADAWTIKTPSREHVLERMVAAIQRWNIKSERNINYRSFEPILSLVRCYETPQCQHWAVWALANLTQVYPEKYCKLVEQENGIQILNELIEHESPYCEIKRIARLVIEQCDSGSERMVVDG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ZER1_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZER1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZER1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZER1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCNE_DROME	CycE	genetic	12242236
HLES_DROME	H	genetic	10835395
ELBOW_DROME	elB	physical	25242320

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZER1_DROME

Related Literatures of Post-Translational Modification