ZBED8_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBED8_HUMAN
• UniProt AC: Q8IZ13
• Protein Name: Protein ZBED8
• Gene Name: ZBED8
• Organism: Homo sapiens (Human).
• Sequence Length: 594
• Protein Sequence: MSKKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFLFNIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQLQQKSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
73	Phosphorylation	LKHMPAPSDQSETLK CCCCCCCCCCHHHHH		22210691
86	Phosphorylation	LKAFGVASHEDTLLQ HHHHCCCCCHHHHHH		22210691
90	Phosphorylation	GVASHEDTLLQASYQ CCCCCHHHHHHHHHH		22210691
95	Phosphorylation	EDTLLQASYQFAYLC HHHHHHHHHHHHHHH		22210691
148	Phosphorylation	LSDDVIHSRIDEMSQ CCCHHHHHHHHHHCH		-
258	Phosphorylation	ENSEFVAYVKKEIPH CCCHHHHHHCHHCCC		-
282	Phosphorylation	PHALVIKTLPTKLRD CCCEEEECCCHHHHH		28555341
285	Phosphorylation	LVIKTLPTKLRDALF EEEECCCHHHHHHHH		28555341
322	Phosphorylation	FEEIGIEYSVLLFHT HHHHCCCEEEEHHHH		22817900
556	Phosphorylation	SSLLHFKTKSRSCFN CHHHCEEECCCCCCC		29083192
558	Phosphorylation	LLHFKTKSRSCFNLS HHCEEECCCCCCCCC		29083192
560	Phosphorylation	HFKTKSRSCFNLSDD CEEECCCCCCCCCHH		29083192
573	Phosphorylation	DDIRVAISKKVPRFS HHHHHHHHHCCCCHH		24719451
574	Ubiquitination	DIRVAISKKVPRFSD HHHHHHHHCCCCHHH		21890473
575	Ubiquitination	IRVAISKKVPRFSDI HHHHHHHCCCCHHHH		22817900
580	Phosphorylation	SKKVPRFSDIIEQKL HHCCCCHHHHHHHHH		21815630

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBED8_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBED8_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBED8_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSF4_HUMAN	HSF4	physical	21900206
CE126_HUMAN	KIAA1377	physical	21900206
EF1G_HUMAN	EEF1G	physical	21900206
EED_HUMAN	EED	physical	21900206
MBTP1_HUMAN	MBTPS1	physical	21900206
CRLF3_HUMAN	CRLF3	physical	28514442
ZN507_HUMAN	ZNF507	physical	28514442
BMAL2_HUMAN	ARNTL2	physical	28514442
ARI3A_HUMAN	ARID3A	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.