Y1765_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y1765_ARATH
• UniProt AC: C0LGE0
• Protein Name: Probable LRR receptor-like serine/threonine-protein kinase At1g07650
• Gene Name: At1g07650
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1014
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MIYLHRIYFIIVLFTLIFHGRLGFSDNNKLHEAEVRALKEIGKKLGKKDWDFNKDPCSGEGTWIVTTYTTKGFESNITCDCSFLPQNSSCHVIRIALKSQNLTGIVPPEFSKLRHLKVLDLSRNSLTGSIPKEWASMRLEDLSFMGNRLSGPFPKVLTRLTMLRNLSLEGNQFSGPIPPDIGQLVHLEKLHLPSNAFTGPLTEKLGLLKNLTDMRISDNNFTGPIPDFISNWTRILKLQMHGCGLDGPIPSSISSLTSLTDLRISDLGGKPSSFPPLKNLESIKTLILRKCKIIGPIPKYIGDLKKLKTLDLSFNLLSGEIPSSFENMKKADFIYLTGNKLTGGVPNYFVERNKNVDVSFNNFTDESSIPSHDCNRVTSNLVESFALGNKSHKGSTCFLQRMPCVHPKRYHLYKLYINCGGGEVKVDKEITYQADDEPKGASMYVLGANKRWALSSTGNFMDNDDDADEYTVQNTSRLSVNASSPSFGLYRTARVSPLSLTYYGICLGNGNYTVNLHFAEIIFTDDNTLYSLGKRLFDIYVQDQLVIKNFNIQEAARGSGKPIIKSFLVNVTDHTLKIGLRWAGKGTTGIPIRGVYGPMISAISVEPNFKPPVYYDTKDIILKVGVPVAAATLLLFIIVGVFWKKRRDKNDIDKELRGLDLQTGTFTLRQIKAATDNFDVTRKIGEGGFGSVYKGELSEGKLIAVKQLSAKSRQGNREFVNEIGMISALQHPNLVKLYGCCVEGNQLILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIAKGLTFLHEESRIKIVHRDIKASNVLLDKDLNAKISDFGLAKLNDDGNTHISTRIAGTIGYMAPEYAMRGYLTEKADVYSFGVVALEIVSGKSNTNFRPTEDFVYLLDWAYVLQERGSLLELVDPTLASDYSEEEAMLMLNVALMCTNASPTLRPTMSQVVSLIEGKTAMQELLSDPSFSTVNPKLKALRNHFWQNELSRSLSFSTSGPRTASANSLVDAEEKTGLLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	N-linked_Glycosylation	TTKGFESNITCDCSF ECCCCCCCCEEEECC	26.79	-
87	N-linked_Glycosylation	DCSFLPQNSSCHVIR EECCCCCCCCCEEEE	33.67	-
101	N-linked_Glycosylation	RIALKSQNLTGIVPP EEEEECCCCCCCCCC	46.81	-
165	N-linked_Glycosylation	TRLTMLRNLSLEGNQ HHHHHHHHCCCCCCC	29.98	-
210	N-linked_Glycosylation	EKLGLLKNLTDMRIS HHHCHHHHHCCCCCC	48.41	-
220	N-linked_Glycosylation	DMRISDNNFTGPIPD CCCCCCCCCCCCCCH	40.63	-
231	N-linked_Glycosylation	PIPDFISNWTRILKL CCCHHHHHHHHHHHH	39.04	-
251	Phosphorylation	GLDGPIPSSISSLTS CCCCCCCCCHHHCCC	40.81	29797451
300	Phosphorylation	IIGPIPKYIGDLKKL CCCCCCHHCCCHHHC	12.55	29797451
318	Phosphorylation	DLSFNLLSGEIPSSF EECHHHHCCCCCCCC	37.23	19880383
362	N-linked_Glycosylation	NVDVSFNNFTDESSI CCCEEECCCCCCCCC	38.90	-
389	N-linked_Glycosylation	VESFALGNKSHKGST HHHHHHCCCCCCCCC	43.43	-
474	N-linked_Glycosylation	ADEYTVQNTSRLSVN CCCCEEECCCEEEEE	35.37	-
481	N-linked_Glycosylation	NTSRLSVNASSPSFG CCCEEEEECCCCCCC	30.63	-
511	N-linked_Glycosylation	GICLGNGNYTVNLHF EEECCCCEEEEEEEE	33.05	-
570	N-linked_Glycosylation	IIKSFLVNVTDHTLK CEEEEEEECCCCCEE	32.87	-
667	Phosphorylation	DLQTGTFTLRQIKAA CCCCCEEEHHHHHHH	22.37	-
751	Phosphorylation	GNQLILVYEYLENNC CCEEEEEEEHHHCCC	8.73	-
809	Phosphorylation	VHRDIKASNVLLDKD EECCCCHHCEEECCC	23.59	-
838	Phosphorylation	DDGNTHISTRIAGTI CCCCCEEEEEECHHH	12.20	30291188
839	Phosphorylation	DGNTHISTRIAGTIG CCCCEEEEEECHHHC	26.03	25561503
844	Phosphorylation	ISTRIAGTIGYMAPE EEEEECHHHCCCCHH	11.38	-
852	Phosphorylation	IGYMAPEYAMRGYLT HCCCCHHHHHHCCCC	12.49	-
987	Phosphorylation	WQNELSRSLSFSTSG HHHHHHHCCCCCCCC	25.62	23776212
989	Phosphorylation	NELSRSLSFSTSGPR HHHHHCCCCCCCCCC	20.56	30291188
991	Phosphorylation	LSRSLSFSTSGPRTA HHHCCCCCCCCCCCC	20.49	23776212
992	Phosphorylation	SRSLSFSTSGPRTAS HHCCCCCCCCCCCCC	35.37	23776212
993	Phosphorylation	RSLSFSTSGPRTASA HCCCCCCCCCCCCCC	45.67	23776212
997	Phosphorylation	FSTSGPRTASANSLV CCCCCCCCCCCCCCC	28.26	23660473
999	Phosphorylation	TSGPRTASANSLVDA CCCCCCCCCCCCCCH	27.63	23111157
1002	Phosphorylation	PRTASANSLVDAEEK CCCCCCCCCCCHHHH	29.50	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y1765_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y1765_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y1765_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
BET12_ARATH	ATBET12	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-989, AND MASSSPECTROMETRY.
PubMed: 19376835