XYLL2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XYLL2_ARATH
• UniProt AC: Q6AWX0
• Protein Name: D-xylose-proton symporter-like 2
• Gene Name: At5g17010
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 503
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Sequence: MALDPEQQQPISSVSREFGKSSGEISPEREPLIKENHVPENYSVVAAILPFLFPALGGLLYGYEIGATSCATISLQSPSLSGISWYNLSSVDVGLVTSGSLYGALFGSIVAFTIADVIGRRKELILAALLYLVGALVTALAPTYSVLIIGRVIYGVSVGLAMHAAPMYIAETAPSPIRGQLVSLKEFFIVLGMVGGYGIGSLTVNVHSGWRYMYATSVPLAVIMGIGMWWLPASPRWLLLRVIQGKGNVENQREAAIKSLCCLRGPAFVDSAAEQVNEILAELTFVGEDKEVTFGELFQGKCLKALIIGGGLVLFQQITGQPSVLYYAPSILQTAGFSAAGDATRVSILLGLLKLIMTGVAVVVIDRLGRRPLLLGGVGGMVVSLFLLGSYYLFFSASPVVAVVALLLYVGCYQLSFGPIGWLMISEIFPLKLRGRGLSLAVLVNFGANALVTFAFSPLKELLGAGILFCGFGVICVLSLVFIFFIVPETKGLTLEEIEAKCL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MALDPEQQQ ------CCCCHHHCC	22.22	22223895
12	Phosphorylation	PEQQQPISSVSREFG HHHCCCCHHHHHHHH	31.22	19880383
13	Phosphorylation	EQQQPISSVSREFGK HHCCCCHHHHHHHHC	25.49	19880383
15	Phosphorylation	QQPISSVSREFGKSS CCCCHHHHHHHHCCC	28.21	19880383
21	Phosphorylation	VSREFGKSSGEISPE HHHHHHCCCCCCCCC	43.91	19880383
22	Phosphorylation	SREFGKSSGEISPER HHHHHCCCCCCCCCC	43.88	19880383
26	Phosphorylation	GKSSGEISPEREPLI HCCCCCCCCCCCCCC	19.19	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XYLL2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XYLL2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XYLL2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP2_ARATH	HHP2	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
TBL18_ARATH	TBL18	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-26, AND MASSSPECTROMETRY.
PubMed: 19376835