XIRP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XIRP2_HUMAN
• UniProt AC: A4UGR9
• Protein Name: Xin actin-binding repeat-containing protein 2
• Gene Name: XIRP2
• Organism: Homo sapiens (Human).
• Sequence Length: 3374
• Subcellular Localization: Cell junction . Colocalizes with actin stress fibers..
• Protein Description: Protects actin filaments from depolymerization..
• Protein Sequence: MSPESGHSRIFEATAGPNKPESGFAEDSAARGEGVSDLHEVVSLKERMARYQAAVSRGDCRSFSANMMEESEMCAVPGGLAKVKKQFEDEITSSRNTFAQYQYQHQNRSEQEAIHSSQVGTSRSSQEMARNEQEGSKVQKIDVHGTEMVSHLEKHTEEVNQASQFHQYVQETVIDTPEDEEIPKVSTKLLKEQFEKSAQEKILYSDKEMTTPAKQIKTESEYEETFKPSSVVSTSSTSCVSTSQRKETSTTRYSDHSVTSSTLAQINATSSGMTEEFPPPPPDVLQTSVDVTAFSQSPELPSPPRRLPVPKDVYSKQRNLYELNRLYKHIHPELRKNLEKDYISEVSEIVSSQMNSGSSVSADVQQARYVFENTNDSSQKDLNSEREYLEWDEILKGEVQSIRWIFENQPLDSINNGSPDEGDISRGIADQEIIAGGDVKYTTWMFETQPIDTLGAYSSDTVENAEKIPELARGDVCTARWMFETRPLDSMNKMHQSQEESAVTISKDITGGDVKTVRYMFETQHLDQLGQLHSVDEVHLLQLRSELKEIKGNVKRSIKCFETQPLYVIRDGSGQMLEIKTVHREDVEKGDVRTARWMFETQPLDTINKDITEIKVVRGISMEENVKGGVSKAKWLFETQPLEKIKESEEVIIEKEKIIGTDVSRKCWMFETQPLDILKEVPDADSLQREEIIGGDVQTTKHLFETLPIEALKDSPDIGKLQKITASEEEKGDVRHQKWIFETQPLEDIRKDKKEYTRTVKLEEVDRGDVKNYTHIFESNNLIKFDASHKIEVEGVTRGAVELNKSLFETTPLYAIQDPLGKYHQVKTVQQEEIVRGDVRSCRWLFETRPIDQFDESIHKFQIIRGISAQEIQTGNVKSAKWLFETQPLDSIKYFSDVEETESKTEQTRDIVKGDVKTCKWLFETQPMESLYEKVSLMTSSEEIHKGDVKTCTWLFETQPLDTIKDDSETAVKLQTVKQEEIQGGDVRTACFLFETENLDSIQGEEVKEIKPVEMDIQAGDVSSMRYKFENQSLDSISSSSEEVLKKIKTLKTEDIQKGNVLNCRWLFENQPIDKIKESQEGDECVKTVTDIQGGDVRKGCFIFETFSLDEIKEESDYISTKKTITEEVIQGDVKSYRMLFETQPLYAIQDREGSYHEVTTVKKEEVIHGDVRGTRWLFETKPLDSINKSETVYVIKSVTQEDIQKGDVSSVRYRFETQPLDQISEESHNIMPSIDHIQGGNVKTSRQFFESENFDKNNYIRTVSVNEIQKGNVKTSTWLFETHTMDELRGEGLEYENIKTVTQEDVQKGDVKQAVWLFENRTFDSIMEAHKGITKMTKEEIPPSDVKTTTWLFETTPLHEFNETRVEKIEIIGKSIKETLEDLYSQKVIQAPGIIIEADEIGDVRMAKYKLMNQASPEIQKEEIIRADLRNIMVNLLSKRDCTEREILISEEEKGNVNLTKTQLLNRSTEFHAEKEEIVKGDVQQAIKNLFSEERSVKKGILIQEDEKGDINMTIYCLLHENDGDTIEREEVIGGDVKRTIHNLLSSTSNNKISERAKIDASERGNVQFFTTCIEAGALDYLKQLHTESNETLTAKKQEGEKEIIGGDVEGTKLLLKKRQSLVERTVSETDIIPGDVHNTVKVFMTEPQSTFGKIPKEEIIKGDLTSTLNSLSQAVNQKTVTKTEEIIKGNMLATLKSLKESSHRWKESKQPDAIPGDIEKAIECLEKATNTKTEILKKELLKDDLETSLRSLKEAQRSFKEVHKEGVIKKDAKAVMAGSSGEQKTDIHQVAVQRNKNSLLQPKPGPFEPAAKWQGGADTLSQTMGKSCHGNLVEERTEVNLPKAPKGTVKIVIDREQNNDALEKSLRRLSNSHHKSNVLESGDKTGVWTDTTGEQHLRDEYMSRQLTSTVSVKNNLTTKESDRAVRELKKDDVFNSIQSAGKTVGKQQTYELRNDHQKMEGFHIKSPKKTKNIKILTDTQSSKPSPTQHPVSMPVGGTYDLSGDFQKQTLLKQETKYSNKDIKKKNINLQPMWQLLPVEQDTSNVTEMKVSEKSHNTFKATNKKRETDVHLKSQDFLMKTNTSTGLKMAMERSLNPINFNPENNVKESECPLPPPSPPPPPPSNASSEIEFPLPPPPPLMMFPEKNGFLPSLSTEKIKAEFESFPGLPLPPPPVDEKSERESSSMFLPPPPPPTPSQKPAHLLSSSAPEKHSGDFMQQYSQKEASNSQNSQAKIITGKTGVLPPPTLPKPKLPKHIKDNKNDFSPKVELATSLSDMECKITTSKDQKKVMVMTSSEHTETKQNVISKSLDERKQLSIDSANCLSHTVPGTSAPRKKQIAPLIKSHSFPESSGQQNPKPYMRKFKTPLMIAEEKYRQQKEEIEKQKQESSYYNIVKTQSQNQHITEVEKEMPLQKTNEEVSLSGIDSECTVVQPSPGSQSNARILGVCSDNQLSTTSPETVAAKRLHHVLAASEDKDKMKKEVLQSSRDIMQSKSACEIKQSHQECSTQQTQQKKYLEQLHLPQSKPISPNFKVKTIKLPTLDHTLNETDHSYESHKQQSEIDVQTFTKKQYLKTKKTEASTECSHKQSLAERHYQLPKKEKRVTVQLPTESIQKNQEDKLKMVPRKQREFSGSDRGKLPGSEEKNQGPSMIGRKEERLITERKHEHLKNKSAPKVVKQKVIDAHLDSQTQNFQQTQIQTAESKAEHKKLPQPYNSLQEEKCLEVKGIQEKQVFSNTKDSKQEITQNKSFFSSVKESQRDDGKGALNIVEFLRKREELQQILSRVKQFEAEPNKSGLKTFQTLLNTIPGWLISEDKREYAVHIAMENNLEKVKEEITHIKTQAEDMLVSYENIIQTAMMSSKTGKPGNKPTSLDETSSKVSNVHVSNNKNSEQKENKIAKEKTVQHQVAAHHEATVRSHVKTHQEIKLDDSNIPPPSLKTRPPSPTFITIESTARRTENPTKNELSQSPKKDSYVEPPPRRPMSQKSEIHRANTSPSPPRSRSEQLVRLKDTTAKLSKGAIPCPAATPVPIVEKRSEIIMSPATLRRQIKIETRGRDSPPTITIPVNINHAASGSFRESVDAQEEIRKVEKRATYVHKDGLNSTDHMVPDTESYDAVEIIRKVAVPPRLSEHTQRYEAANRTVQMAENFVNDPENEINRWFREFEHGPVSEAKSNRRVYAKGETNHNIQQESRTFCKEEFGLTSLGNTSFTDFSCKHPRELREKIPVKQPRICSETRSLSEHFSGMDAFESQIVESKMKTSSSHSSEAGKSGCDFKHAPPTYEDVIAGHILDISDSPKEVRKNFQKTWQESGRVFKGLGYATADASATEMRTTFQEESAFISEAAAPRQGNMYTLSKDSLSNGVPSGRQAEFS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41 (in isoform 1)	Phosphorylation	-	2.17	27251275
41 (in isoform 4)	Phosphorylation	-	2.17	27251275
41 (in isoform 6)	Phosphorylation	-	2.17	27251275
41 (in isoform 8)	Phosphorylation	-	2.17	27251275
51	Phosphorylation	LKERMARYQAAVSRG HHHHHHHHHHHHHCC	7.93	18083107
90 (in isoform 4)	Phosphorylation	-	40.75	-
90 (in isoform 6)	Phosphorylation	-	40.75	-
90 (in isoform 8)	Phosphorylation	-	40.75	-
109	Phosphorylation	QYQHQNRSEQEAIHS HHHHCCCCHHHHHHH	51.70	26437602
117	Phosphorylation	EQEAIHSSQVGTSRS HHHHHHHHCCCCCHH	18.09	26437602
143 (in isoform 4)	Phosphorylation	-	5.23	30177828
143 (in isoform 6)	Phosphorylation	-	5.23	30177828
143 (in isoform 8)	Phosphorylation	-	5.23	30177828
146 (in isoform 4)	Phosphorylation	-	13.16	29116813
146 (in isoform 6)	Phosphorylation	-	13.16	29116813
146 (in isoform 8)	Phosphorylation	-	13.16	29116813
151 (in isoform 4)	Phosphorylation	-	26.97	30177828
151 (in isoform 6)	Phosphorylation	-	26.97	30177828
151 (in isoform 8)	Phosphorylation	-	26.97	30177828
155 (in isoform 4)	Phosphorylation	-	29.18	30177828
155 (in isoform 6)	Phosphorylation	-	29.18	30177828
155 (in isoform 8)	Phosphorylation	-	29.18	30177828
160 (in isoform 4)	Phosphorylation	-	34.67	30177828
160 (in isoform 6)	Phosphorylation	-	34.67	30177828
160 (in isoform 8)	Phosphorylation	-	34.67	30177828
197	Phosphorylation	LKEQFEKSAQEKILY HHHHHHHHHHHHHHC	28.17	24425749
204	Phosphorylation	SAQEKILYSDKEMTT HHHHHHHCCCHHCCC	20.49	18083107
205	Phosphorylation	AQEKILYSDKEMTTP HHHHHHCCCHHCCCC	38.47	24425749
302	Phosphorylation	SQSPELPSPPRRLPV CCCCCCCCCCCCCCC	61.23	17081983
350 (in isoform 7)	Phosphorylation	-	3.85	24275569
364 (in isoform 7)	Phosphorylation	-	4.55	27067055
388	Phosphorylation	DLNSEREYLEWDEIL CCHHHHHHHHHHHHH	19.01	22985185
397 (in isoform 5)	Phosphorylation	-	36.54	24275569
411 (in isoform 5)	Phosphorylation	-	6.09	27067055
413	Phosphorylation	FENQPLDSINNGSPD HHCCCCCCCCCCCCC	34.59	22673903
418	Phosphorylation	LDSINNGSPDEGDIS CCCCCCCCCCCCCCC	31.16	22673903
425	Phosphorylation	SPDEGDISRGIADQE CCCCCCCCCCCCCCE	29.24	22673903
459	Phosphorylation	DTLGAYSSDTVENAE CCCCCCCCCCCCCHH	25.32	-
461	Phosphorylation	LGAYSSDTVENAEKI CCCCCCCCCCCHHHC	31.50	-
497	Phosphorylation	SMNKMHQSQEESAVT HHHHHCCCHHHHCEE	25.53	26437602
519	Phosphorylation	GDVKTVRYMFETQHL CCHHEEEEEEECCCH	11.21	-
549 (in isoform 7)	Phosphorylation	-	63.66	-
572 (in isoform 4)	Phosphorylation	-	24.67	24275569
586 (in isoform 4)	Phosphorylation	-	54.56	27067055
596 (in isoform 5)	Phosphorylation	-	25.44	-
605 (in isoform 6)	Phosphorylation	-	52.83	24275569
608 (in isoform 7)	Phosphorylation	-	37.73	-
612	Phosphorylation	DTINKDITEIKVVRG CCCCCCCCEEEEEEC	41.62	29759185
618 (in isoform 7)	Phosphorylation	-	39.45	-
619 (in isoform 6)	Phosphorylation	-	12.52	27067055
621	Phosphorylation	IKVVRGISMEENVKG EEEEECCCCCHHCCC	23.98	24719451
655 (in isoform 5)	Phosphorylation	-	54.63	-
665 (in isoform 5)	Phosphorylation	-	37.69	-
712 (in isoform 7)	Phosphorylation	-	4.03	25852190
713 (in isoform 7)	Phosphorylation	-	64.31	25852190
715 (in isoform 7)	Phosphorylation	-	23.92	25852190
759 (in isoform 5)	Phosphorylation	-	17.75	25852190
760 (in isoform 5)	Phosphorylation	-	6.33	25852190
762 (in isoform 5)	Phosphorylation	-	6.20	25852190
771 (in isoform 4)	Phosphorylation	-	49.31	-
796 (in isoform 1)	Phosphorylation	-	1.77	24719451
804 (in isoform 6)	Phosphorylation	-	20.54	-
830 (in isoform 4)	Phosphorylation	-	50.64	-
840 (in isoform 4)	Phosphorylation	-	34.48	-
863 (in isoform 6)	Phosphorylation	-	2.33	-
868	Phosphorylation	FQIIRGISAQEIQTG HHEEECCCHHHCCCC	27.07	26437602
873 (in isoform 6)	Phosphorylation	-	42.47	-
925	Phosphorylation	TCKWLFETQPMESLY HCHHHHCCCCCHHHH	30.55	25907765
930	Phosphorylation	FETQPMESLYEKVSL HCCCCCHHHHHHHCC	29.96	25907765
932	Phosphorylation	TQPMESLYEKVSLMT CCCCHHHHHHHCCCC	24.00	25907765
934 (in isoform 4)	Phosphorylation	-	24.46	25852190
935 (in isoform 4)	Phosphorylation	-	3.38	25852190
937 (in isoform 4)	Phosphorylation	-	4.93	25852190
940	Phosphorylation	EKVSLMTSSEEIHKG HHHCCCCCCCHHHCC	23.06	26437602
963	Phosphorylation	FETQPLDTIKDDSET EECCCCCCCCCCCHH	37.29	-
967 (in isoform 6)	Phosphorylation	-	43.29	25852190
968	Phosphorylation	LDTIKDDSETAVKLQ CCCCCCCCHHEEEEE	47.16	23663014
968 (in isoform 6)	Phosphorylation	-	47.16	25852190
970	Phosphorylation	TIKDDSETAVKLQTV CCCCCCHHEEEEEEE	40.48	23663014
970 (in isoform 6)	Phosphorylation	-	40.48	25852190
1027	Phosphorylation	GDVSSMRYKFENQSL CCCCCCEEEECCCCH	16.04	28270605
1033	Phosphorylation	RYKFENQSLDSISSS EEEECCCCHHCCCCC	45.80	28270605
1036	Phosphorylation	FENQSLDSISSSSEE ECCCCHHCCCCCHHH	29.66	28270605
1038	Phosphorylation	NQSLDSISSSSEEVL CCCHHCCCCCHHHHH	28.28	28270605
1039	Phosphorylation	QSLDSISSSSEEVLK CCHHCCCCCHHHHHH	35.89	28270605
1040	Phosphorylation	SLDSISSSSEEVLKK CHHCCCCCHHHHHHH	34.67	28270605
1041	Phosphorylation	LDSISSSSEEVLKKI HHCCCCCHHHHHHHH	39.46	28270605
1137	Phosphorylation	IQGDVKSYRMLFETQ HCCCHHHEEEEEECC	8.37	-
1263	Phosphorylation	DKNNYIRTVSVNEIQ CCCCEEEEEEHHHHH	13.94	26437602
1265	Phosphorylation	NNYIRTVSVNEIQKG CCEEEEEEHHHHHCC	20.72	24719451
1283	Phosphorylation	TSTWLFETHTMDELR EEEEEEEEECHHHHC	18.47	-
1285	Phosphorylation	TWLFETHTMDELRGE EEEEEEECHHHHCCC	33.46	-
1303	Phosphorylation	YENIKTVTQEDVQKG CCCCEEECHHHHHCC	31.32	-
1349	Phosphorylation	IPPSDVKTTTWLFET CCHHHCCCCEEEEEC	29.34	26657352
1350	Phosphorylation	PPSDVKTTTWLFETT CHHHCCCCEEEEECC	15.40	26657352
1351	Phosphorylation	PSDVKTTTWLFETTP HHHCCCCEEEEECCC	25.96	26657352
1440 (in isoform 1)	Phosphorylation	-	52.83	24719451
1461	Phosphorylation	EKGNVNLTKTQLLNR HCCCCCCCHHHHHCC	27.17	-
1463	Phosphorylation	GNVNLTKTQLLNRST CCCCCCHHHHHCCCC	21.15	26437602
1469	Phosphorylation	KTQLLNRSTEFHAEK HHHHHCCCCCCHHCH	31.08	26437602
1541	Phosphorylation	IGGDVKRTIHNLLSS CCHHHHHHHHHHHHC	22.37	25954137
1547	Phosphorylation	RTIHNLLSSTSNNKI HHHHHHHHCCCCCCC	34.43	25954137
1603	Ubiquitination	AKKQEGEKEIIGGDV EEEHHCCCEECCCCC	66.14	-
1611	Ubiquitination	EIIGGDVEGTKLLLK EECCCCCHHHHHHHH	66.92	32015554
1622	Phosphorylation	LLLKKRQSLVERTVS HHHHHHHHHHHCCCC	38.11	26437602
1627	Phosphorylation	RQSLVERTVSETDII HHHHHHCCCCCCCCC	18.19	23532336
1629	Phosphorylation	SLVERTVSETDIIPG HHHHCCCCCCCCCCC	33.88	21712546
1631	Phosphorylation	VERTVSETDIIPGDV HHCCCCCCCCCCCCC	25.62	21712546
1652	Phosphorylation	FMTEPQSTFGKIPKE EECCCCCCCCCCCHH	31.03	-
1667	Phosphorylation	EIIKGDLTSTLNSLS HHCCCCHHHHHHHHH	25.14	17929957
1672	Phosphorylation	DLTSTLNSLSQAVNQ CHHHHHHHHHHHHHC	32.29	-
1674	Phosphorylation	TSTLNSLSQAVNQKT HHHHHHHHHHHHCCC	18.86	-
1722	Acetylation	AIPGDIEKAIECLEK CCCCCHHHHHHHHHH	55.81	7933599
1729	Acetylation	KAIECLEKATNTKTE HHHHHHHHHCCCCHH	47.78	7933611
1766	Acetylation	RSFKEVHKEGVIKKD HHHHHHHHCCCCCCC	62.43	7461907
1771	Acetylation	VHKEGVIKKDAKAVM HHHCCCCCCCCCHHH	42.04	7461919
1796	Dimethylation	IHQVAVQRNKNSLLQ HHHHHHHCCCCCCCC	49.87	-
1833	Ubiquitination	MGKSCHGNLVEERTE CCHHCCCCCEECCCC	19.76	32015554
1877	Methylation	RLSNSHHKSNVLESG HHHHCCHHHCCCCCC	38.00	23748837
1887	Phosphorylation	VLESGDKTGVWTDTT CCCCCCCCCCEECCC	41.53	-
1903	Phosphorylation	EQHLRDEYMSRQLTS CHHHHHHHHHCCCCC	12.51	28270605
1905	Phosphorylation	HLRDEYMSRQLTSTV HHHHHHHHCCCCCCE	18.90	28270605
1909	Phosphorylation	EYMSRQLTSTVSVKN HHHHCCCCCCEEECC	17.64	26437602
1910	Phosphorylation	YMSRQLTSTVSVKNN HHHCCCCCCEEECCC	35.09	28270605
1911	Phosphorylation	MSRQLTSTVSVKNNL HHCCCCCCEEECCCC	16.15	28270605
1913	Phosphorylation	RQLTSTVSVKNNLTT CCCCCCEEECCCCCC	27.71	28270605
1923	Phosphorylation	NNLTTKESDRAVREL CCCCCHHHHHHHHHH	33.67	-
1938	Phosphorylation	KKDDVFNSIQSAGKT HHHHHHHHHHHCCCC	15.56	28290473
1941	Phosphorylation	DVFNSIQSAGKTVGK HHHHHHHHCCCCCCC	37.00	30631047
1944	Methylation	NSIQSAGKTVGKQQT HHHHHCCCCCCCCHH	39.49	23748837
1945	Phosphorylation	SIQSAGKTVGKQQTY HHHHCCCCCCCCHHE	33.31	-
1951	Phosphorylation	KTVGKQQTYELRNDH CCCCCCHHEECCCCH	19.23	26437602
1968	Phosphorylation	MEGFHIKSPKKTKNI CCCCCCCCCCCCCCE	41.15	26437602
1989	Phosphorylation	QSSKPSPTQHPVSMP CCCCCCCCCCCCCCC	43.79	-
1994	Phosphorylation	SPTQHPVSMPVGGTY CCCCCCCCCCCCCEE	23.09	-
2048	Phosphorylation	EQDTSNVTEMKVSEK CCCCCCCCEEEECHH	34.31	-
2069	Phosphorylation	ATNKKRETDVHLKSQ CCCCCCCCCCEECHH	47.56	-
2085	Phosphorylation	FLMKTNTSTGLKMAM HHHHCCCCHHHHHHH	23.65	-
2184	Phosphorylation	DEKSERESSSMFLPP CCCCCCCCCCCCCCC	33.65	28450419
2185	Phosphorylation	EKSERESSSMFLPPP CCCCCCCCCCCCCCC	22.52	28450419
2186	Phosphorylation	KSERESSSMFLPPPP CCCCCCCCCCCCCCC	23.88	28450419
2196	Phosphorylation	LPPPPPPTPSQKPAH CCCCCCCCCCCCCHH	41.15	28450419
2198	Phosphorylation	PPPPPTPSQKPAHLL CCCCCCCCCCCHHHH	54.00	28450419
2222	Phosphorylation	GDFMQQYSQKEASNS CCHHHHHHHHHHHCC	30.36	26437602
2229	Phosphorylation	SQKEASNSQNSQAKI HHHHHHCCCCCCCEE	28.39	-
2232	Phosphorylation	EASNSQNSQAKIITG HHHCCCCCCCEEECC	24.71	-
2238	Phosphorylation	NSQAKIITGKTGVLP CCCCEEECCCCCCCC	35.78	-
2266	Phosphorylation	KDNKNDFSPKVELAT CCCCCCCCCCHHHHH	27.03	24719451
2276	Phosphorylation	VELATSLSDMECKIT HHHHHHHHHCCCEEE	34.38	-
2286	Acetylation	ECKITTSKDQKKVMV CCEEECCCCCCCEEE	63.18	19824803
2295	Phosphorylation	QKKVMVMTSSEHTET CCCEEEEECCCCCHH	20.07	22210691
2296	Phosphorylation	KKVMVMTSSEHTETK CCEEEEECCCCCHHH	18.68	28509920
2297	Phosphorylation	KVMVMTSSEHTETKQ CEEEEECCCCCHHHH	25.00	28509920
2300	Phosphorylation	VMTSSEHTETKQNVI EEECCCCCHHHHHHH	41.10	29083192
2302	Phosphorylation	TSSEHTETKQNVISK ECCCCCHHHHHHHHC	38.80	29759185
2318	Phosphorylation	LDERKQLSIDSANCL HHHHHCCCCCCCHHH	23.12	26437602
2346	Phosphorylation	QIAPLIKSHSFPESS HHHHHHHHCCCCCCC	19.85	26437602
2348	Phosphorylation	APLIKSHSFPESSGQ HHHHHHCCCCCCCCC	49.98	26437602
2361	Phosphorylation	GQQNPKPYMRKFKTP CCCCCCCCHHHCCCC	18.71	-
2398	Phosphorylation	SYYNIVKTQSQNQHI HHHHHEECCCCCCCC	23.66	26437602
2400	Phosphorylation	YNIVKTQSQNQHITE HHHEECCCCCCCCCH	36.01	26437602
2406	Phosphorylation	QSQNQHITEVEKEMP CCCCCCCCHHHHHCC	31.67	30622161
2474	Phosphorylation	LHHVLAASEDKDKMK HHHHHHCCCCHHHHH	40.49	26437602
2494	Phosphorylation	SSRDIMQSKSACEIK HHHHHHHCCHHHHHH	15.93	28355574
2517	Phosphorylation	QQTQQKKYLEQLHLP HHHHHHHHHHHCCCC	23.62	26437602
2530	Phosphorylation	LPQSKPISPNFKVKT CCCCCCCCCCCEEEE	23.48	26437602
2537	Phosphorylation	SPNFKVKTIKLPTLD CCCCEEEEEECCCCC	26.74	26437602
2542	Phosphorylation	VKTIKLPTLDHTLNE EEEEECCCCCCCCCC	56.08	26437602
2582	Phosphorylation	KTKKTEASTECSHKQ HCCCCCCCCHHHHHH	20.64	25690035
2583	Phosphorylation	TKKTEASTECSHKQS CCCCCCCCHHHHHHH	48.32	25690035
2590	Phosphorylation	TECSHKQSLAERHYQ CHHHHHHHHHHHHCC	34.06	22985185
2606	Phosphorylation	PKKEKRVTVQLPTES CCCCCCEEEECCHHH	13.43	26437602
2613	Phosphorylation	TVQLPTESIQKNQED EEECCHHHHHHCHHH	32.56	28258704
2635	Phosphorylation	KQREFSGSDRGKLPG CCCCCCCCCCCCCCC	23.96	21815630
2643	Phosphorylation	DRGKLPGSEEKNQGP CCCCCCCCCCCCCCC	40.41	26437602
2717	Phosphorylation	KLPQPYNSLQEEKCL CCCCCCCCCCHHHHH	26.11	26437602
2727	Ubiquitination	EEKCLEVKGIQEKQV HHHHHHCCCCCEEEC	40.70	-
2739	Ubiquitination	KQVFSNTKDSKQEIT EECCCCCCCCHHHHH	65.34	-
2796	Phosphorylation	FEAEPNKSGLKTFQT HHCCCCCCCHHHHHH	56.87	22210691
2799	Methylation	EPNKSGLKTFQTLLN CCCCCCHHHHHHHHH	51.31	-
2814	Phosphorylation	TIPGWLISEDKREYA HCCCCCCCCCHHHHH	37.26	22210691
2820	Phosphorylation	ISEDKREYAVHIAME CCCCHHHHHHHHHHH	20.25	19835603
2864	Phosphorylation	TAMMSSKTGKPGNKP HHHHHCCCCCCCCCC	53.00	26437602
2872	Phosphorylation	GKPGNKPTSLDETSS CCCCCCCCCCCCCCC	43.46	20886841
2873	Phosphorylation	KPGNKPTSLDETSSK CCCCCCCCCCCCCCC	42.21	26437602
2877	Phosphorylation	KPTSLDETSSKVSNV CCCCCCCCCCCCCCE	37.66	24275569
2878	Phosphorylation	PTSLDETSSKVSNVH CCCCCCCCCCCCCEE	26.56	24275569
2882	Phosphorylation	DETSSKVSNVHVSNN CCCCCCCCCEEECCC	36.55	30576142
2887	Phosphorylation	KVSNVHVSNNKNSEQ CCCCEEECCCCCCHH	21.58	17929957
2940	Ubiquitination	NIPPPSLKTRPPSPT CCCCCCCCCCCCCCC	46.99	-
2941	Phosphorylation	IPPPSLKTRPPSPTF CCCCCCCCCCCCCCE	54.42	26437602
2945	Phosphorylation	SLKTRPPSPTFITIE CCCCCCCCCCEEEEE	38.97	26437602
2947	Phosphorylation	KTRPPSPTFITIEST CCCCCCCCEEEEECC	31.82	28348404
2954	Phosphorylation	TFITIESTARRTENP CEEEEECCCCCCCCC	16.05	-
2958	Phosphorylation	IESTARRTENPTKNE EECCCCCCCCCCCCC	34.26	22210691
2967	Phosphorylation	NPTKNELSQSPKKDS CCCCCCCCCCCCCCC	23.57	23663014
2969	Phosphorylation	TKNELSQSPKKDSYV CCCCCCCCCCCCCCC	35.00	23663014
2988	Phosphorylation	RRPMSQKSEIHRANT CCCCCCCHHHHHCCC	33.86	26437602
2995	Phosphorylation	SEIHRANTSPSPPRS HHHHHCCCCCCCCCC	40.82	20166139
2996	Phosphorylation	EIHRANTSPSPPRSR HHHHCCCCCCCCCCC	24.16	23927012
2998	Phosphorylation	HRANTSPSPPRSRSE HHCCCCCCCCCCCHH	47.51	23927012
3002	Phosphorylation	TSPSPPRSRSEQLVR CCCCCCCCCHHHHHH	46.03	20166139
3004	Phosphorylation	PSPPRSRSEQLVRLK CCCCCCCHHHHHHHH	30.82	26437602
3037	Phosphorylation	VPIVEKRSEIIMSPA CCCEECCCEEECCHH	44.19	26437602
3042	Phosphorylation	KRSEIIMSPATLRRQ CCCEEECCHHHHHHH	10.85	26437602
3054	Phosphorylation	RRQIKIETRGRDSPP HHHHEEEECCCCCCC	41.73	23403867
3059	Phosphorylation	IETRGRDSPPTITIP EEECCCCCCCEEEEE	31.27	26437602
3120 (in isoform 1)	Phosphorylation	-	2.72	24719451
3131	Phosphorylation	VAVPPRLSEHTQRYE HCCCCCCCHHHHHHH	28.72	24719451
3170	Phosphorylation	REFEHGPVSEAKSNR HHCCCCCHHHHHHCC	10.79	20166139
3173	Phosphorylation	EHGPVSEAKSNRRVY CCCCHHHHHHCCCEE	17.05	20166139
3177	Phosphorylation	VSEAKSNRRVYAKGE HHHHHHCCCEEECCC	36.21	20166139
3212 (in isoform 1)	Phosphorylation	-	35.58	27251275
3239	Phosphorylation	RICSETRSLSEHFSG CCCCCCCCHHHHHCC	43.60	26437602
3241	Phosphorylation	CSETRSLSEHFSGMD CCCCCCHHHHHCCHH	30.21	26437602
3295	Phosphorylation	AGHILDISDSPKEVR HCEEEECCCCHHHHH	31.53	22673903
3297	Phosphorylation	HILDISDSPKEVRKN EEEECCCCHHHHHHH	30.95	26437602
3306 (in isoform 1)	Phosphorylation	-	52.22	24719451
3357	Phosphorylation	QGNMYTLSKDSLSNG CCCCEEECHHHHCCC	26.98	23532336
3362	Phosphorylation	TLSKDSLSNGVPSGR EECHHHHCCCCCCCC	35.17	23532336
3367	Phosphorylation	SLSNGVPSGRQAEFS HHCCCCCCCCCCCCC	44.17	26670566
3374	Phosphorylation	SGRQAEFS------- CCCCCCCC-------	30.71	26670566

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XIRP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XIRP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XIRP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NEBU_HUMAN	NEB	physical	23985323
NEBL_HUMAN	NEBL	physical	23985323
FLNC_HUMAN	FLNC	physical	23115302
ACTS_CHICK	ACTA1	physical	15454575

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.