ACTS_CHICK - dbPTM
ACTS_CHICK - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ACTS_CHICK
UniProt AC P68139
Protein Name Actin, alpha skeletal muscle
Gene Name ACTA1
Organism Gallus gallus (Chicken).
Sequence Length 377
Subcellular Localization Cytoplasm, cytoskeleton.
Protein Description Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells..
Protein Sequence MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MCDEDETTA
------CCCCCCCEE
8.68-
3Acetylation-----MCDEDETTAL
-----CCCCCCCEEE
66.15456601
46OxidationRPRHQGVMVGMGQKD
CCCCCCEEEECCCCC
2.49-
49OxidationHQGVMVGMGQKDSYV
CCCEEEECCCCCCCC
3.32-
75MethylationTLKYPIEHGIITNWD
EEECEECCCCCCCHH
33.2112356759
86MethylationTNWDDMEKIWHHTFY
CCHHHHHHHHHHHHH
44.45-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ACTS_CHICK !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ACTS_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ACTS_CHICK !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ACTS_CHICKACTA1physical
18160294
TPM1_PIGTPM1physical
15454575

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ACTS_CHICK

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Related Literatures of Post-Translational Modification

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