VCL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VCL1_ARATH
• UniProt AC: Q93VQ0
• Protein Name: Protein VACUOLELESS1
• Gene Name: VCL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 858
• Subcellular Localization: Vacuole membrane ; Peripheral membrane protein . Prevacuolar compartment membrane ; Peripheral membrane protein .
• Protein Description: Required for vacuole biogenesis and vacuole enlargment in dividing and expanding cells. Involved in the docking or fusion of prevacuolar vesicles. Important for the function of both male and female gametophytes, but is not essential for the germination and development of pollen..
• Protein Sequence: MANVSVAAEWQLLYDRYYRKPEIYQMKWKHVDLSRNKVACASFGGPIAVIRDDSKIVQLYAESALRKLRIFNSAGILLSETVWKHPGGRLIGMSWSDDQTLICIVQDGTIYRYNIHAELIEPNMSMGQECFEQNVVECVFWGNGVVCLTEGGQLICIFDFKTMKPSKLPDVPGLAEDDLLQPICLTVREPKYTMSGIAEVLVAVGDDIFVVEEDMVQTIRFDEPSVDDSEMQNDDSGNLIGVVQKMIVSPNGKFLTLFTHDGRIVVVDMETKQIAIDYSCESALPPQQMAWCGMDSVLLYWDEDLMMVGPVGDPVHYFYDEPIILIPECDGVRILSNTNLEFLQRVPDSTESIFKIGSTSPAALLYDALDHFDRRSAKADENLRLIRSSLSEAVESCIDAAGHEFDVTRQRALLRAASYGQAFCSNFQRERVQETCRTLRVLNAVRDPAIGIPLSIQQYKLLTPVVLISRLINANCHLLALRISEYLDMNKEVVIMHWACAKITASPSTPDSHLLEILLDKLQLCKGISYAAVATHADNCGRRKLAAMLVEHEPRSTKQVPLLLSIGEEDTALVKATESGDTDLVYLVIFHIWQKRPPLEFFAMIQGRVLARDLFVAYARCHKHEFLKDFFLSTGQIHEVAFLLWKESWDMGKNPMASKGSPLHGPRIKLIEKARNLFSQTKEHTFESKAAEEHAKLLKIQHELEASTKQAIFVDSSINDTIRTCIVLGNNRAAIKVKTEFKVSDKRWYWLKAFALATIKDWAALEKFSKEKRPPMGFRPFVEACIDADEKAEALKYIPKLSDLVERGEAYARIGMAKEAADCAAQANDGGELLERFRKTFVQNAIFDTLLMPFQGAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
661	Phosphorylation	NPMASKGSPLHGPRI CCCCCCCCCCCCHHH		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VCL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VCL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VCL1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS33_ARATH	ATVPS33	physical	12589039
VPS11_ARATH	VPS11	physical	12589039
SYP22_ARATH	VAM3	physical	12589039
SYP21_ARATH	SYP21	physical	12589039

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.