VPS33_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VPS33_ARATH
• UniProt AC: Q94KJ7
• Protein Name: Vacuolar protein-sorting-associated protein 33 homolog
• Gene Name: VPS33
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 592
• Subcellular Localization: Vacuole membrane ; Peripheral membrane protein . Prevacuolar compartment membrane ; Peripheral membrane protein .
• Protein Description: Involved in regulating membrane fusion at the tonoplast and the prevacuolar compartment..
• Protein Sequence: MAQIPSLENAPLNLKSIRDKSERELVNLLKDVRGTKCLVIDPKLSGSVSLIIPTSKLKELGLELRHLTAEPVQTECTKVVYLVRSQLSFMKFIASHIQNDIAKAIQRDYYVYFVPRRSVACEKILEQEKVHNLVTVKEFPLYMVPLDEDVISFELELSEKDCLVDGDVSSLWHIAKAIHELEFSFGVISKMRAKGKASVRVADILNRMQVEEPVNSNDVGRPEVDTLILLDREVDMVTPMCSQLTYEGLIDEILHISNGAVEVDSSVMGAQQEGKKMKVPLNSSDKLFKETRDLNFEVVVQVLRQKAMTMKEDYTEINSTQTVSELKDFVKKLNSLPEMTRHIHLAQHLTTFTSKQSFNSQLDMEQTLVEAENYDICYEYIEEMIHKQEPLTNVLRLLVLFSVTNSGLPKKQFDYIRMELLHSYGFEHVVTLNNLEKAGLLKKQEFKSNWLTVKRTLKLIVEDTDTSRPNDIAYVYSGYAPLSIRLIQQAIHSGWRPMEDILKLLPGPHLETKRSGFPSSPSVDSLHGASNGVADGRRSIVLVVFIGGVTFAEISALRYLASKEGMAYDLIVATTKIVNGATLIETFMEKLG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAQIPSLEN ------CCCCCCCCC	18.93	22223895
6	Phosphorylation	--MAQIPSLENAPLN --CCCCCCCCCCCCC	50.36	23328941
448	Phosphorylation	LKKQEFKSNWLTVKR CCCHHCHHCCEEHHH	38.26	24894044
519	Phosphorylation	TKRSGFPSSPSVDSL CCCCCCCCCCCHHHC	53.25	19880383
520	Phosphorylation	KRSGFPSSPSVDSLH CCCCCCCCCCHHHCC	22.79	19880383
522	Phosphorylation	SGFPSSPSVDSLHGA CCCCCCCCHHHCCCC	40.27	30291188
525	Phosphorylation	PSSPSVDSLHGASNG CCCCCHHHCCCCCCC	21.80	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VPS33_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VPS33_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VPS33_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of VPS33_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.