dbPTM

UTRO_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UTRO_HUMAN
UniProt AC	P46939
Protein Name	Utrophin
Gene Name	UTRN
Organism	Homo sapiens (Human).
Sequence Length	3433
Subcellular Localization	Cell junction, synapse, postsynaptic cell membrane Peripheral membrane protein Cytoplasmic side. Cytoplasm, cytoskeleton. Neuromuscular junction.
Protein Description	May play a role in anchoring the cytoskeleton to the plasma membrane..
Protein Sequence	MAKYGEHEASPDNGQNEFSDIIKSRSDEHNDVQKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKAQTYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLPQQVTIDAIREVETLPRKYKKECEEEAINIQSTAPEEEHESPRAETPSTVTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKEEALNKVQTSNFKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQIHVDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQILVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKEEWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMARASCSALMSQPSAPDFVQRGFDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQVSLNVLNDLAKVEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRSGPVAGIKTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQEKAANLKKDLAEMQEWMTQAEEEYLERDFEYKSPEELESAVEEMKRAKEDVLQKEVRVKILKDNIKLLAAKVPSGGQELTSELNVVLENYQLLCNRIRGKCHTLEEVWSCWIELLHYLDLETTWLNTLEERMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQIRELGQTLIDGGILDDIISEKLEAFNSRYEDLSHLAESKQISLEKQLQVLRETDQMLQVLQESLGELDKQLTTYLTDRIDAFQVPQEAQKIQAEISAHELTLEELRRNMRSQPLTSPESRTARGGSQMDVLQRKLREVSTKFQLFQKPANFEQRMLDCKRVLDGVKAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARKMKKEAASLSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAALQNLIEGSEPILEERLCVLNAGWSRVRTWTEDWCNTLMNHQNQLEIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQLLLLHTRYNKIKAIPIQQRKMGQLASGIRSSLLPTDYLVEINKILLCMDDVELSLNVPELNTAIYEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGPEAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQKRSTTELGENLQELRDLTQEMEVHAEKLKWLNRTELEMLSDKSLSLPERDKISESLRTVNMTWNKICREVPTTLKECIQEPSSVSQTRIAAHPNVQKVVLVSSASDIPVQSHRTSEISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEARLYILQQARRDPLTKQISDNQILLQELGPGDGIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDASHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPALQLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRNLQSKTELTPEERAQKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKEAESVRNGWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSPLDLHPSLKMSRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNEIFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQSLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQIPRQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEHYDPSQSPQLFHDDTHSRIEQYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQTLGGESPVSQPQSPAQILKSVEREERGELERIIADLEEEQRNLQVEYEQLKDQHLRRGLPVGSPPESIISPHHTSEDSELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPSCCPNVPSRPQAM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAKYGEHEASP ----CCCCCCCCCCC	34.50	21712546
10	Phosphorylation	KYGEHEASPDNGQNE CCCCCCCCCCCCCCC	29.78	30266825
19	Phosphorylation	DNGQNEFSDIIKSRS CCCCCCHHHHHHCCC	23.01	28555341
47	Acetylation	WINARFSKSGKPPIN HHHHHHCCCCCCCCC	61.59	7429219
74	Phosphorylation	LDLLEGLTGTSLPKE HHHHHHCCCCCCCCC	49.63	22210691
76	Phosphorylation	LLEGLTGTSLPKERG HHHHCCCCCCCCCCC	23.12	22210691
77	Phosphorylation	LEGLTGTSLPKERGS HHHCCCCCCCCCCCC	43.98	24719451
84	O-linked_Glycosylation	SLPKERGSTRVHALN CCCCCCCCCHHHHHH	21.18	31492838
85	O-linked_Glycosylation	LPKERGSTRVHALNN CCCCCCCCHHHHHHH	39.26	31492838
158	Phosphorylation	NSEKILLSWVRQTTR CHHHHHHHHHHHCCC	21.78	26270265
163	Phosphorylation	LLSWVRQTTRPYSQV HHHHHHHCCCCCCCE	17.76	26270265
164	Phosphorylation	LSWVRQTTRPYSQVN HHHHHHCCCCCCCEE	22.70	26270265
268	Phosphorylation	DAIREVETLPRKYKK HHHHHHHCCCHHHHH	47.43	24670416
274	Sumoylation	ETLPRKYKKECEEEA HCCCHHHHHHHHHHH	45.17	-
286	Phosphorylation	EEAINIQSTAPEEEH HHHHCCCCCCCHHHC	23.80	22167270
287	Phosphorylation	EAINIQSTAPEEEHE HHHCCCCCCCHHHCC	29.83	22167270
295	Phosphorylation	APEEEHESPRAETPS CCHHHCCCCCCCCCC	22.92	30266825
300	Phosphorylation	HESPRAETPSTVTEV CCCCCCCCCCCCEEE	22.89	22468782
302	Phosphorylation	SPRAETPSTVTEVDM CCCCCCCCCCEEEEC	42.82	24275569
360	Phosphorylation	EAFMMELTAHQSSVG HHHHHHHHCCCCCHH	14.59	-
381	Phosphorylation	NQLITQGTLSDEEEF CEEEECCCCCCHHHH	17.17	-
446	O-linked_Glycosylation	ERIQKMETCPLDDDV HHHHHHCCCCCCHHH	18.87	31492838
464	Ubiquitination	QKLLEEHKSLQSDLE HHHHHHHHHHHHHHH	57.02	-
468	Phosphorylation	EEHKSLQSDLEAEQV HHHHHHHHHHHHHHH	49.83	-
548	Ubiquitination	LKAWLTEKEEALNKV HHHHHHHHHHHHHHH	56.47	-
569	Phosphorylation	DQKELSVSVRRLAIL CHHHHHHHHHHHHHH	13.41	-
604	Phosphorylation	VGQLLDNSKASKKIN HHHHHCCCHHHHCCC	29.30	22199227
612	Phosphorylation	KASKKINSDSEELTQ HHHHCCCCCHHHHHH	46.09	-
623	Phosphorylation	ELTQRWDSLVQRLED HHHHHHHHHHHHHHH	24.39	24275569
631	Phosphorylation	LVQRLEDSSNQVTQA HHHHHHHCCHHHHHH	23.08	30257219
632	Phosphorylation	VQRLEDSSNQVTQAV HHHHHHCCHHHHHHH	43.53	30257219
664	Phosphorylation	RVREQAITKKSKQEL HHHHHHHHHHHHCCC	35.12	29083192
667	Phosphorylation	EQAITKKSKQELPPP HHHHHHHHHCCCCCC	40.92	29083192
712	Phosphorylation	KWKTAIQTTEIKEYM HHHHHHHHHHHHHHH	21.93	20068231
713	Phosphorylation	WKTAIQTTEIKEYMK HHHHHHHHHHHHHHH	21.24	20068231
718	Phosphorylation	QTTEIKEYMKMQDTS HHHHHHHHHHCCCHH	9.31	23879269
724	Phosphorylation	EYMKMQDTSEMKKKL HHHHCCCHHHHHHHH	15.08	-
725	Phosphorylation	YMKMQDTSEMKKKLK HHHCCCHHHHHHHHH	43.94	-
784	Phosphorylation	SSEWKNVSQHLEDLE HHHHHHHHHHHHHHH	22.67	20363803
803	Phosphorylation	LQEDINAYFKQLDEL HHHHHHHHHHHHHHH	13.56	23879269
824	Phosphorylation	KEEWVKHTSISESSR HHHHHHHCCCCHHHH	23.26	23403867
825	Phosphorylation	EEWVKHTSISESSRQ HHHHHHCCCCHHHHH	24.68	23401153
827	Phosphorylation	WVKHTSISESSRQSL HHHHCCCCHHHHHCC	31.06	30266825
829	Phosphorylation	KHTSISESSRQSLPS HHCCCCHHHHHCCCC	24.83	30266825
830	Phosphorylation	HTSISESSRQSLPSL HCCCCHHHHHCCCCH	30.22	30266825
833	Phosphorylation	ISESSRQSLPSLKDS CCHHHHHCCCCHHHH	40.93	23403867
836	Phosphorylation	SSRQSLPSLKDSCQR HHHHCCCCHHHHHHH	54.03	23403867
863	Phosphorylation	EMARASCSALMSQPS HHHHHHHHHHHCCCC	23.18	28857561
870	Phosphorylation	SALMSQPSAPDFVQR HHHHCCCCCHHHHHH	44.81	28857561
881	Phosphorylation	FVQRGFDSFLGRYQA HHHHCHHHHHHHHHH	21.80	21815630
896	Methylation	VQEAVEDRQQHLENE HHHHHHHHHHHHHHH	25.26	115919721
926	Phosphorylation	LKDVLNDSENKAQVS HHHHHCCCCCHHHHH	41.83	22964224
933	Phosphorylation	SENKAQVSLNVLNDL CCCHHHHHHHHHHHH	11.35	27251275
986	Phosphorylation	HPDVEKLYKQEFDDV CCCHHHHHHCCCCCC	22.99	29759185
1005	Phosphorylation	NKLKVLVSKDLHLLE HHHHHHHCCCHHHHH	19.11	22210691
1017	Phosphorylation	LLEEIALTLRAFEAD HHHHHHHHHHHHHCC	12.74	28348404
1025	Phosphorylation	LRAFEADSTVIEKWM HHHHHCCHHHHHHHH	31.46	22210691
1026	Phosphorylation	RAFEADSTVIEKWMD HHHHCCHHHHHHHHH	26.50	22210691
1102	Phosphorylation	VQTRLGDYQTQLEKL HHHHCCHHHHHHHHH	16.20	-
1104	Phosphorylation	TRLGDYQTQLEKLSK HHCCHHHHHHHHHHH	28.97	-
1258	Phosphorylation	TLEERMKSTEVLPEK HHHHHHHCCCCCCCH	22.06	22817900
1259	Phosphorylation	LEERMKSTEVLPEKT HHHHHHCCCCCCCHH	25.29	22817900
1265	Ubiquitination	STEVLPEKTDAVNEA CCCCCCCHHHHHHHH	50.17	-
1266	Phosphorylation	TEVLPEKTDAVNEAL CCCCCCHHHHHHHHH	27.77	22817900
1275	Phosphorylation	AVNEALESLESVLRH HHHHHHHHHHHHHCC	37.98	18767875
1308	Phosphorylation	GILDDIISEKLEAFN CHHHHHHHHHHHHHH	29.07	24719451
1334	Ubiquitination	SKQISLEKQLQVLRE HCCCCHHHHHHHHHH	62.70	21890473
1361	Phosphorylation	GELDKQLTTYLTDRI HHHHHHHHHHHHHHC	15.76	22210691
1367	Methylation	LTTYLTDRIDAFQVP HHHHHHHHCCCCCCC	24.37	115919713
1385	Phosphorylation	QKIQAEISAHELTLE HHHHHHHHHHHCCHH	18.32	22210691
1390	Phosphorylation	EISAHELTLEELRRN HHHHHHCCHHHHHHH	29.19	22210691
1400	Phosphorylation	ELRRNMRSQPLTSPE HHHHHHHCCCCCCCH	25.94	23403867
1404	Phosphorylation	NMRSQPLTSPESRTA HHHCCCCCCCHHCCC	49.25	30266825
1405	Phosphorylation	MRSQPLTSPESRTAR HHCCCCCCCHHCCCC	34.06	30266825
1408	Phosphorylation	QPLTSPESRTARGGS CCCCCCHHCCCCCCC	38.01	30266825
1412	Methylation	SPESRTARGGSQMDV CCHHCCCCCCCHHHH	49.76	115919717
1415	Phosphorylation	SRTARGGSQMDVLQR HCCCCCCCHHHHHHH	25.75	28857561
1417	Sulfoxidation	TARGGSQMDVLQRKL CCCCCCHHHHHHHHH	4.05	30846556
1484	Phosphorylation	KCMKLYKTLSEVKLE HHHHHHHHHHHCCCC	23.20	-
1486	Phosphorylation	MKLYKTLSEVKLEVE HHHHHHHHHCCCCEE	45.64	27251275
1514	Sulfoxidation	QTDNPKGMDEQLTSL CCCCCCCHHHHHHHH	6.82	30846556
1551	Ubiquitination	QLARKMKKEAASLSE HHHHHHHHHHHHHHH	49.43	-
1603	Phosphorylation	KRKADLNTITESSAA HHHCCHHHHCHHHHH	36.25	20860994
1605	Phosphorylation	KADLNTITESSAALQ HCCHHHHCHHHHHHH	27.98	20860994
1695	Phosphorylation	EIVKRLVSELDDANL HHHHHHHHHHHHCCC	36.71	26471730
1720	Phosphorylation	ILMNARGSSSRELVE HHHCCCCCCCHHHHH	21.42	-
1741	Phosphorylation	NRNFEKVSQHIKSAK HHHHHHHHHHHHHHH	27.40	22985185
1746	Phosphorylation	KVSQHIKSAKLLIAQ HHHHHHHHHHHHHHC	29.99	22817900
1757	Phosphorylation	LIAQEPLYQCLVTTE HHHCCCHHHHHCCCC	14.11	25159151
1795	Phosphorylation	FVEKHLESSDEDEKM HHHHHHHCCCCCHHH	49.83	26657352
1796	Phosphorylation	VEKHLESSDEDEKMD HHHHHHCCCCCHHHH	35.33	26657352
1815	Methylation	QIEEVLQRGEEMLHQ HHHHHHHHHHHHHCC	50.78	24384361
1861	Phosphorylation	RKMGQLASGIRSSLL HHHHHHHHHHHHHCC	43.26	23403867
1865	Phosphorylation	QLASGIRSSLLPTDY HHHHHHHHHCCCHHH	24.34	29691806
1866	Phosphorylation	LASGIRSSLLPTDYL HHHHHHHHCCCHHHH	24.87	30278072
1870	Phosphorylation	IRSSLLPTDYLVEIN HHHHCCCHHHHHHHC	36.93	25072903
1872	Phosphorylation	SSLLPTDYLVEINKI HHCCCHHHHHHHCEE	18.35	27251275
1919	Ubiquitination	NIKDQLDKLGEQIAV HHHHHHHHHHHHHHH	67.97	-
1949	Phosphorylation	EAIQIRDTLTQLNAK CCHHHHHHHHHHHHH	23.12	21406692
1951	Phosphorylation	IQIRDTLTQLNAKWD HHHHHHHHHHHHHHH	32.86	21406692
2008	Phosphorylation	DTCAPGGSLDLEKAR HHCCCCCCCCHHHHC	25.32	24275569
2052	Phosphorylation	KLSQADGSFLKEKLA HHHHCCCCHHHHHHH	28.14	24719451
2111	Phosphorylation	EHAMQKRSTTELGEN HHHHHHCCHHHHHHH	46.87	26657352
2112	Phosphorylation	HAMQKRSTTELGENL HHHHHCCHHHHHHHH	28.46	28857561
2113	Phosphorylation	AMQKRSTTELGENLQ HHHHCCHHHHHHHHH	30.38	27251275
2161	Phosphorylation	LPERDKISESLRTVN CCCHHHHHHHHHHHH	27.20	24719451
2163	Phosphorylation	ERDKISESLRTVNMT CHHHHHHHHHHHHCH	19.16	25278378
2180	Phosphorylation	KICREVPTTLKECIQ HHHHHCCCCHHHHHH	50.35	25690035
2181	Phosphorylation	ICREVPTTLKECIQE HHHHCCCCHHHHHHC	29.75	25690035
2210	Phosphorylation	VQKVVLVSSASDIPV CCEEEEEECCCCCCC	18.94	30266825
2210	O-linked_Glycosylation	VQKVVLVSSASDIPV CCEEEEEECCCCCCC	18.94	31492838
2211	Phosphorylation	QKVVLVSSASDIPVQ CEEEEEECCCCCCCC	25.06	30266825
2213	Phosphorylation	VVLVSSASDIPVQSH EEEEECCCCCCCCCC	37.71	30266825
2219	Phosphorylation	ASDIPVQSHRTSEIS CCCCCCCCCCCCCCC	18.38	25159151
2222	Phosphorylation	IPVQSHRTSEISIPA CCCCCCCCCCCCCCC	25.86	30266825
2223	Phosphorylation	PVQSHRTSEISIPAD CCCCCCCCCCCCCCC	32.65	30266825
2226	Phosphorylation	SHRTSEISIPADLDK CCCCCCCCCCCCHHH	20.61	23403867
2255	Phosphorylation	MLKSNIVTVGDVEEI HHHCCCCEECCHHHH	18.25	-
2264	Ubiquitination	GDVEEINKTVSRMKI CCHHHHHHHHHHHCC	56.84	-
2285	Phosphorylation	QRHPQLDYVFTLAQN HHCCCHHHHHHHHHH	13.17	-
2300	Phosphorylation	LKNKASSSDMRTAIT HHHCCCCHHHHHHHH	32.69	24719451
2304	Phosphorylation	ASSSDMRTAITEKLE CCCHHHHHHHHHHHH	18.77	24719451
2307	Phosphorylation	SDMRTAITEKLERVK HHHHHHHHHHHHHHH	25.30	24719451
2309	Ubiquitination	MRTAITEKLERVKNQ HHHHHHHHHHHHHHH	47.18	-
2355	Phosphorylation	TEELMRKYEARLYIL HHHHHHHHHHHHHHH	12.40	22817900
2360	Phosphorylation	RKYEARLYILQQARR HHHHHHHHHHHHHHC	8.27	22817900
2375	Phosphorylation	DPLTKQISDNQILLQ CCCCCCCCCCHHHHH	28.19	24043423
2419	Phosphorylation	NVKETTEYLKTSWIN CHHHHHHHHHHHHHC	16.06	-
2422	Phosphorylation	ETTEYLKTSWINLKQ HHHHHHHHHHHCHHH	27.05	29052541
2423	Phosphorylation	TTEYLKTSWINLKQS HHHHHHHHHHCHHHH	25.11	29052541
2482	Phosphorylation	RENALQDSILARELK HHHHHHHHHHHHHHH	13.41	27499020
2567	Phosphorylation	KWNRLLMSLEELIKW HHHHHHHHHHHHHHH	32.38	27251275
2573	Ubiquitination	MSLEELIKWLNMKDE HHHHHHHHHHCCCCH	59.25	21906983
2599	Phosphorylation	VPALQLQYDHCKALR CCHHHHHHHHHHHHH	19.08	26356563
2612	Ubiquitination	LRRELKEKEYSVLNA HHHHHHHHHHHHHHH	61.43	-
2614	Phosphorylation	RELKEKEYSVLNAVD HHHHHHHHHHHHHHH	18.36	28857561
2615	Phosphorylation	ELKEKEYSVLNAVDQ HHHHHHHHHHHHHHH	22.63	26657352
2644	Phosphorylation	EPRRNLQSKTELTPE CHHCCCCCCCCCCHH	44.72	28857561
2645	Ubiquitination	PRRNLQSKTELTPEE HHCCCCCCCCCCHHH	32.81	-
2646	Phosphorylation	RRNLQSKTELTPEER HCCCCCCCCCCHHHH	41.28	26270265
2649	Phosphorylation	LQSKTELTPEERAQK CCCCCCCCHHHHHHH	23.56	21815630
2665	Phosphorylation	AKAMRKQSSEVKEKW HHHHHHCCHHHHHHH	31.34	20068231
2666	Phosphorylation	KAMRKQSSEVKEKWE HHHHHCCHHHHHHHH	43.87	20068231
2684	Ubiquitination	AVTSNWQKQVDKALE HHHHHHHHHHHHHHH	43.85	-
2718	Ubiquitination	ESVRNGWKPVGDLLI HHHHCCCCCHHHHHH	31.09	-
2750	Ubiquitination	APINFKVKTVNDLSS CCCCCEEEEHHHHHH	47.55	-
2756	Phosphorylation	VKTVNDLSSQLSPLD EEEHHHHHHCCCCCC	20.92	25850435
2757	Phosphorylation	KTVNDLSSQLSPLDL EEHHHHHHCCCCCCC	42.30	25850435
2760	Phosphorylation	NDLSSQLSPLDLHPS HHHHHCCCCCCCCCH	18.77	25850435
2769	Ubiquitination	LDLHPSLKMSRQLDD CCCCCHHHHHHHHHH	38.88	-
2793	Ubiquitination	VSVDDRLKQLQEAHR CCHHHHHHHHHHHHH	50.27	-
2821	Phosphorylation	VQLPWQRSISHNKVP CCCCCCCCCCCCCCC	17.22	23312004
2823	Phosphorylation	LPWQRSISHNKVPYY CCCCCCCCCCCCCEE	23.43	23312004
2826	Ubiquitination	QRSISHNKVPYYINH CCCCCCCCCCEEEEC	38.88	-
2829	Phosphorylation	ISHNKVPYYINHQTQ CCCCCCCEEEECCCC	21.69	23312004
2830	Phosphorylation	SHNKVPYYINHQTQT CCCCCCEEEECCCCC	6.81	23312004
2835	Phosphorylation	PYYINHQTQTTCWDH CEEEECCCCCCCCCC	21.97	23312004
2837	Phosphorylation	YINHQTQTTCWDHPK EEECCCCCCCCCCHH	27.58	23312004
2838	Phosphorylation	INHQTQTTCWDHPKM EECCCCCCCCCCHHH	11.20	23312004
2851	Phosphorylation	KMTELFQSLADLNNV HHHHHHHHHHHHCCC	20.42	28857561
2861	Phosphorylation	DLNNVRFSAYRTAIK HHCCCCHHHHHHHHH	17.52	24719451
2891	Ubiquitination	STTNEIFKQHKLNQN HCHHHHHHHCCCCCC	58.09	-
2894	Ubiquitination	NEIFKQHKLNQNDQL HHHHHHCCCCCCCCC	46.79	-
2971	Ubiquitination	SKGLLEEKYRYLFKE CCCHHHHHHHHHHHH	26.17	-
2985	Sulfoxidation	EVAGPTEMCDQRQLG HHHCCHHHCCHHHHH	3.16	21406390
3019	Phosphorylation	GGSNIEPSVRSCFQQ CCCCCCHHHHHHHHH	19.85	28857561
3048	Phosphorylation	WMHLEPQSMVWLPVL HHHCCCCHHCHHHHH	26.47	20068231
3065	Ubiquitination	VAAAETAKHQAKCNI HHHHHHHHHHHCCCC	43.60	2190698
3069	Ubiquitination	ETAKHQAKCNICKEC HHHHHHHCCCCCCCC	22.65	-
3074	Ubiquitination	QAKCNICKECPIVGF HHCCCCCCCCCCCCE	59.56	-
3087	Methylation	GFRYRSLKHFNYDVC CEEECCCCCCCCCCH	47.61	115978859
3096	Phosphorylation	FNYDVCQSCFFSGRT CCCCCHHHCCCCCCC	14.04	28857561
3111	Phosphorylation	AKGHKLHYPMVEYCI CCCCCCCCCCEEEEC	11.94	23822953
3151	Phosphorylation	AKHPRLGYLPVQTVL CCCCCCCCCCCEEEE	16.66	-
3156	Phosphorylation	LGYLPVQTVLEGDNL CCCCCCEEEECCCCC	27.56	-
3165	Phosphorylation	LEGDNLETPITLISM ECCCCCCCCEEEEEC	24.13	18669648
3180	Phosphorylation	WPEHYDPSQSPQLFH CCCCCCCCCCCCCCC	40.15	18669648
3182	Phosphorylation	EHYDPSQSPQLFHDD CCCCCCCCCCCCCCC	20.96	18669648
3197	Phosphorylation	THSRIEQYATRLAQM HHHHHHHHHHHHHHH	9.35	28796482
3199	Phosphorylation	SRIEQYATRLAQMER HHHHHHHHHHHHHHH	22.68	28796482
3215	Phosphorylation	NGSFLTDSSSTTGSV CCCCCCCCCCCCCCC	22.43	28348404
3216	Phosphorylation	GSFLTDSSSTTGSVE CCCCCCCCCCCCCCC	34.22	28348404
3217	Phosphorylation	SFLTDSSSTTGSVED CCCCCCCCCCCCCCC	33.66	28348404
3218	Phosphorylation	FLTDSSSTTGSVEDE CCCCCCCCCCCCCCH	36.80	28348404
3219	Phosphorylation	LTDSSSTTGSVEDEH CCCCCCCCCCCCCHH	29.43	28348404
3221	Phosphorylation	DSSSTTGSVEDEHAL CCCCCCCCCCCHHHH	21.90	28348404
3232	Phosphorylation	EHALIQQYCQTLGGE HHHHHHHHHHHHCCC	3.11	29802988
3235	Phosphorylation	LIQQYCQTLGGESPV HHHHHHHHHCCCCCC	24.65	29802988
3240	Phosphorylation	CQTLGGESPVSQPQS HHHHCCCCCCCCCCC	33.60	29802988
3243	Phosphorylation	LGGESPVSQPQSPAQ HCCCCCCCCCCCHHH	39.26	-
3247	Phosphorylation	SPVSQPQSPAQILKS CCCCCCCCHHHHHHH	28.96	26657352
3254	Phosphorylation	SPAQILKSVEREERG CHHHHHHHHHHHHHC	26.26	25159151
3281	Phosphorylation	QRNLQVEYEQLKDQH HHHHHHCHHHHHHHH	15.32	28796482
3297	Phosphorylation	RRGLPVGSPPESIIS HCCCCCCCCCHHHCC	37.20	25159151
3301	Phosphorylation	PVGSPPESIISPHHT CCCCCCHHHCCCCCC	30.88	22199227
3304	Phosphorylation	SPPESIISPHHTSED CCCHHHCCCCCCCCC	19.26	25159151
3308	Phosphorylation	SIISPHHTSEDSELI HHCCCCCCCCCHHHH	30.67	29978859
3309	Phosphorylation	IISPHHTSEDSELIA HCCCCCCCCCHHHHH	34.74	29978859
3312	Phosphorylation	PHHTSEDSELIAEAK CCCCCCCHHHHHHHH	30.19	29978859
3358	Phosphorylation	QLLEQPESDSRINGV HHHHCCCCCCCCCCC	47.79	-
3360	Phosphorylation	LEQPESDSRINGVSP HHCCCCCCCCCCCCC	44.32	21815630

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1258	S	Phosphorylation	Kinase	MARK2	Q7KZI7	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	MARCHF5	Q9NX47	PMID:22199232

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UTRO_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UTRO_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UTRO_HUMAN	UTRN	physical	10647184
DTNA_HUMAN	DTNA	physical	9701558
MARK2_HUMAN	MARK2	physical	19945424
ZC3HF_HUMAN	ZC3H15	physical	22939629
XPO4_HUMAN	XPO4	physical	22939629
DTNA_HUMAN	DTNA	physical	10767429
DAG1_HUMAN	DAG1	physical	10767429

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UTRO_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-4; SER-10; SER-3297 ANDSER-3304, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3180 AND SER-3182, ANDMASS SPECTROMETRY.	18220336 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-295, AND MASSSPECTROMETRY.	17081983 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1266, AND MASSSPECTROMETRY.	18187866 [Abstract]