UL35_HCMVM - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UL35_HCMVM
• UniProt AC: F5HE12
• Protein Name: Tegument protein UL35
• Gene Name: UL35
• Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
• Sequence Length: 641
• Subcellular Localization: Isoform UL35: Virion tegument. Host nucleus. Found in nuclear bodies.; Isoform UL35a: Host nucleus.
• Protein Description: Plays important role in immediate-early gene expression through interaction with UL82. Forms nuclear bodies in host nucleus, independently of PML. In turn, UL35 nuclear bodies associate with and remodel PML bodies (By similarity).; Isoform UL35a promotes cytoplasmic UL82 accumulation and inhibits UL35-containing nuclear bodies formation..
• Protein Sequence: MAQGSRAPSGPPLPVLPVDDWLNFRVDLFGDEHRRLLLEMLTQGCSNFVGLLNFGVPSPVYALEALVDFQVRNAFMKVKPVAQEIIRICILANHYRNSRDVLRDLRTQLDVLYSEPLKTRLLRGLIRLCRAAQTGVKPEDISVHLGADDVTFGVLKRALVRLHRVRDALGLRASPEAEARYPRLTTYNLLFHPPPFTTVEAVDLCAENLSDVTQRRNRPLRCLTSIKRPGSRTLEDALNDMYLLLTLRHLQLRHALELQMMQDWVVERCNRLCDALYFCYTQAPETRQTFVTLVRGLELARQHSSPAFQPMLYNLLQLLTQLHEANVYLCPGYLHFSAYKLLKKIQSVSDARERGEFGDEDEEQENDGEPREAQLDLEADPTAREGELFFFSKNLYGNGEVFRVPEQPSRYLRRRMFVERPETLQIFYNFHEGKITTETYHLQRIYSMMIEGASRQTGLTPKRFMELLDRAPLGQESEPEITEHRDLFADVFRRPVTDAASSSSASSSSSSASPNSVSLPSARSSSTRTTTPASTYTSAGTSSTTGLLLSSSSLSGSHGISSADLEQPPRQRRRMVSVTLFSPYSVAYSHHRRHRRRRSPPPAPRGPAHTRFQGPDSMPSTSYGSDVEDPRDDLAENLRHL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of UL35_HCMVM !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UL35_HCMVM !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UL35_HCMVM !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UL35_HCMVM !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DCAF1_HUMAN	VPRBP	physical	22072767
DDB1_HUMAN	DDB1	physical	22072767
DDA1_HUMAN	DDA1	physical	22072767
SART3_HUMAN	SART3	physical	22072767
UBP7_HUMAN	USP7	physical	22072767
OGT1_HUMAN	OGT	physical	22072767
IPO4_HUMAN	IPO4	physical	22072767

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.