UBP29_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UBP29_HUMAN
• UniProt AC: Q9HBJ7
• Protein Name: Ubiquitin carboxyl-terminal hydrolase 29
• Gene Name: USP29
• Organism: Homo sapiens (Human).
• Sequence Length: 922
• Protein Sequence: MISLKVCGFIQIWSQKTGMTKLKEALIETVQRQKEIKLVVTFKSGKFIRIFQLSNNIRSVVLRHCKKRQSHLRLTLKNNVFLFIDKLSYRDAKQLNMFLDIIHQNKSQQPMKSDDDWSVFESRNMLKEIDKTSFYSICNKPSYQKMPLFMSKSPTHVKKGILENQGGKGQNTLSSDVQTNEDILKEDNPVPNKKYKTDSLKYIQSNRKNPSSLEDLEKDRDLKLGPSFNTNCNGNPNLDETVLATQTLNAKNGLTSPLEPEHSQGDPRCNKAQVPLDSHSQQLQQGFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVPWEYIPFEALIMTLTQLLALKDFCSTKIKRELLGNVKKVISAVAEIFSGNMQNDAHEFLGQCLDQLKEDMEKLNATLNTGKECGDENSSPQMHVGSAATKVFVCPVVANFEFELQLSLICKACGHAVLKVEPNNYLSINLHQETKPLPLSIQNSLDLFFKEEELEYNCQMCKQKSCVARHTFSRLSRVLIIHLKRYSFNNAWLLVKNNEQVYIPKSLSLSSYCNESTKPPLPLSSSAPVGKCEVLEVSQEMISEINSPLTPSMKLTSESSDSLVLPVEPDKNADLQRFQRDCGDASQEQHQRDLENGSALESELVHFRDRAIGEKELPVADSLMDQGDISLPVMYEDGGKLISSPDTRLVEVHLQEVPQHPELQKYEKTNTFVEFNFDSVTESTNGFYDCKENRIPEGSQGMAEQLQQCIEESIIDEFLQQAPPPGVRKLDAQEHTEETLNQSTELRLQKADLNHLGALGSDNPGNKNILDAENTRGEAKELTRNVKMGDPLQAYRLISVVSHIGSSPNSGHYISDVYDFQKQAWFTYNDLCVSEISETKMQEARLHSGYIFFYMHNGIFEELLRKAENSRLPSTQAGVIPQGEYEGDSLYRPA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
44	Phosphorylation	KLVVTFKSGKFIRIF EEEEEECCCCEEEEE	42.92	-
504	Phosphorylation	RHTFSRLSRVLIIHL HHHHHHHHHHHHEEE	21.16	-
585	Phosphorylation	TPSMKLTSESSDSLV CCCCCCCCCCCCCCE	46.01	18491316
672	Phosphorylation	DGGKLISSPDTRLVE ECCEEECCCCCCEEE	21.57	21815630
808	Acetylation	ENTRGEAKELTRNVK CCCHHHHHHHHHCCC	49.29	7427871
815	Acetylation	KELTRNVKMGDPLQA HHHHHCCCCCCHHHH	40.49	7427879
876	Phosphorylation	MQEARLHSGYIFFYM HHHHHHCCCEEEEEE	37.57	19835603
878	Phosphorylation	EARLHSGYIFFYMHN HHHHCCCEEEEEEEC	9.51	19835603
882	Phosphorylation	HSGYIFFYMHNGIFE CCCEEEEEEECCHHH	6.16	19835603

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UBP29_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UBP29_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UBP29_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CATB_HUMAN	CTSB	physical	19615732
P53_HUMAN	TP53	physical	21285945
CLSPN_HUMAN	CLSPN	physical	24632611
ZEB1_HUMAN	ZEB1	physical	29119051

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.